New study lays to rest concerns about virtual colonoscopy as a screening tool

November 01, 2004

Virtual colonoscopy can effectively detect flat lesions in the colon, a study of more than 1,200 patients shows. The study results lay to rest concerns that virtual colonoscopy should not be used as a screening tool to detect colon cancer because it can't detect these lesions, the study authors say.

"Studies from Asia have indicated that flat lesions are quite common, and often turn into cancer," said Perry Pickhardt, MD, associate professor of radiology at the University of Wisconsin Medical School in Madison. "Therefore it has been argued that virtual colonoscopy should not be used as a screening tool if it misses these lesions," he said.

However this study found that virtual colonoscopy detected 80% of the flat lesions (47 of 59 lesions) that were 6mm or more in size. Virtual colonoscopy detected 81% of the non-flat lesions, Dr. Pickhardt said. Twenty-nine of the 59 flat lesions were adenomas, which are potential precursors to cancer, said Dr. Pickhardt. Virtual colonoscopy detected 83% of the flat adenomas. It detected 86% (156 of 181) non-flat adenomas, he added. "It is apparent that virtual colonoscopy is equally good for detecting both flat and non-flat types of lesions," he said.

The study also found that flat adenomas are "uncommon in a typical western screening population, and advanced flat neoplasms are rare," said Dr. Pickhardt. The study found no diminutive flat lesions that were histologically advanced in the 1,233 patients screened with virtual colonoscopy, he said.

The study was sponsored by the Department of Defense and was conducted at the National Naval Medical Center in Bethesda, MD, Walter Reed Army Medical Center in Washington, DC, and the Naval Medical Center in San Diego, CA. All patients underwent both a virtual colonoscopy and a standard (optical) colonoscopy. All were considered "healthy" at the time of the colonoscopy examinations.

The study was published in the November 2004 issue of the American Journal of Roentgenology.
-end-


American College of Radiology

Related Cancer Articles from Brightsurf:

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications.

UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies
A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.

Breast cancer treatment costs highest among young women with metastic cancer
In a fight for their lives, young women, age 18-44, spend double the amount of older women to survive metastatic breast cancer, according to a large statewide study by the University of North Carolina at Chapel Hill.

Cancer mortality continues steady decline, driven by progress against lung cancer
The cancer death rate declined by 29% from 1991 to 2017, including a 2.2% drop from 2016 to 2017, the largest single-year drop in cancer mortality ever reported.

Stress in cervical cancer patients associated with higher risk of cancer-specific mortality
Psychological stress was associated with a higher risk of cancer-specific mortality in women diagnosed with cervical cancer.

Cancer-sniffing dogs 97% accurate in identifying lung cancer, according to study in JAOA
The next step will be to further fractionate the samples based on chemical and physical properties, presenting them back to the dogs until the specific biomarkers for each cancer are identified.

Moffitt Cancer Center researchers identify one way T cell function may fail in cancer
Moffitt Cancer Center researchers have discovered a mechanism by which one type of immune cell, CD8+ T cells, can become dysfunctional, impeding its ability to seek and kill cancer cells.

More cancer survivors, fewer cancer specialists point to challenge in meeting care needs
An aging population, a growing number of cancer survivors, and a projected shortage of cancer care providers will result in a challenge in delivering the care for cancer survivors in the United States if systemic changes are not made.

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment.

American Cancer Society outlines blueprint for cancer control in the 21st century
The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that forms the basis of a national cancer control plan.

Read More: Cancer News and Cancer Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.