Nav: Home

Nanomaterials for neurology: State-of-the-art

November 01, 2016

Despite the numerous challenges associated with the application of nanotechnology in neuroscience, it promises to have a significant impact on our understanding of how the nervous system works, how it fails in disease, and the development of earlier and less-invasive diagnostic procedures so we can intervene in the pre-clinical stage of neurological disease before extensive neurological damage has taken place.

Chronic neurodegenerative disorders are disease processes in which intrinsic functions of brain cells and systems are progressively altered. The enormous growth in our understanding of the brain that has taken place over the past several decades has not been accompanied by a comparable increase in the efficacy of treatment of neurological disorders.

Because nanotechnology uses bio-engineered systems that interact with biological systems at a molecular level, it can offer impressive improvement in the treatment of these disorders. Nanotechnological tools operate on a dimensional scale that facilitates physical interactions with neurons as well as with the smaller glial cells. These small-scale tools and devices have great potential for medicinal and pharmaceutical applications. Nanomedicine has already made the current drug regimen more effective with attributes like sustained release, increased half-life, higher drug concentrations at target sites, reduced toxicity and fewer side effects.

Nanotechnology shows great promise for the diagnosis and therapy of neurodegenerative disorders by supporting and promoting functional regeneration of damaged neurons, providing neuroprotection, and enabling the delivery of drugs, growth factors, genes and cells across the blood brain barrier.

In this review we provide a neurobiological overview of key neurological disorders and describe the different types of nanomaterials in use. We present many of the different applications that advances in nanotechnology are having in the field of neurological sciences and discuss the issue of toxicity of the nanomaterials.

In conclusion, we weigh in on what the promises and challenges lie ahead of researchers for future developments in this groundbreaking field.
For More information about the article, please visit

Reference: Veloz-Castillo, M.F.; et al (2016). Nanomaterials for Neurology: State-of-the-Art. CNS Neurol. Disord. Drug Targets., DOI: 10.2174/1871527315666160801144637

Bentham Science Publishers

Related Neurons Articles:

A molecule that directs neurons
A research team coordinated by the University of Trento studied a mass of brain cells, the habenula, linked to disorders like autism, schizophrenia and depression.
Shaping the social networks of neurons
Identification of a protein complex that attracts or repels nerve cells during development.
With these neurons, extinguishing fear is its own reward
The same neurons responsible for encoding reward also form new memories to suppress fearful ones, according to new research by scientists at The Picower Institute for Learning and Memory at MIT.
How do we get so many different types of neurons in our brain?
SMU (Southern Methodist University) researchers have discovered another layer of complexity in gene expression, which could help explain how we're able to have so many billions of neurons in our brain.
These neurons affect how much you do, or don't, want to eat
University of Arizona researchers have identified a network of neurons that coordinate with other brain regions to influence eating behaviors.
Mood neurons mature during adolescence
Researchers have discovered a mysterious group of neurons in the amygdala -- a key center for emotional processing in the brain -- that stay in an immature, prenatal developmental state throughout childhood.
Connecting neurons in the brain
Leuven researchers uncover new mechanisms of brain development that determine when, where and how strongly distinct brain cells interconnect.
The salt-craving neurons
Pass the potato chips, please! New research discovers neural circuits that regulate craving and satiation for salty tastes.
When neurons are out of shape, antidepressants may not work
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed medication for major depressive disorder (MDD), yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD.
Losing neurons can sometimes not be that bad
Current thinking about Alzheimer's disease is that neuronal cell death in the brain is to blame for the cognitive havoc caused by the disease.
More Neurons News and Neurons Current Events

Trending Science News

Current Coronavirus (COVID-19) News

Top Science Podcasts

We have hand picked the top science podcasts of 2020.
Now Playing: TED Radio Hour

Listen Again: Reinvention
Change is hard, but it's also an opportunity to discover and reimagine what you thought you knew. From our economy, to music, to even ourselves–this hour TED speakers explore the power of reinvention. Guests include OK Go lead singer Damian Kulash Jr., former college gymnastics coach Valorie Kondos Field, Stockton Mayor Michael Tubbs, and entrepreneur Nick Hanauer.
Now Playing: Science for the People

#562 Superbug to Bedside
By now we're all good and scared about antibiotic resistance, one of the many things coming to get us all. But there's good news, sort of. News antibiotics are coming out! How do they get tested? What does that kind of a trial look like and how does it happen? Host Bethany Brookeshire talks with Matt McCarthy, author of "Superbugs: The Race to Stop an Epidemic", about the ins and outs of testing a new antibiotic in the hospital.
Now Playing: Radiolab

Dispatch 6: Strange Times
Covid has disrupted the most basic routines of our days and nights. But in the middle of a conversation about how to fight the virus, we find a place impervious to the stalled plans and frenetic demands of the outside world. It's a very different kind of front line, where urgent work means moving slow, and time is marked out in tiny pre-planned steps. Then, on a walk through the woods, we consider how the tempo of our lives affects our minds and discover how the beats of biology shape our bodies. This episode was produced with help from Molly Webster and Tracie Hunte. Support Radiolab today at