Ants swallow their own acid to protect themselves from germs

November 03, 2020

Ants use their own acid to disinfect themselves and their stomachs. A team from Martin Luther University Halle-Wittenberg (MLU) and the University of Bayreuth has found that formic acid kills harmful bacteria in the animal's food, thereby reducing the risk of disease. At the same time, the acid significantly influences the ant's intestinal flora. The new study was published in the journal eLife.

Formic acid is one of the simplest organic acids. It is produced in a special gland in the abdomen of numerous species of ant. "There was a long-standing assumption that the acid only served to ward off predators, for example insects and birds," says Dr Simon Tragust from the Institute of Biology at MLU, who co-led the new study alongside Professor Heike Feldhaar from Bayreuth. A couple of years ago he was able to show that ants also use the acid in brood care, for example, to disinfect their brood and prevent the spread of harmful fungi.

The new study was based on an observation of the animals' behaviour. "Whenever ants swallow food or water, they start cleaning their hindquarters afterwards," says Tragust. The researcher wanted to figure out why they do that. "For one thing, the behaviour didn't seem to be linked to digestion, because ants do this even after they have only ingested water," he adds.

Through several experiments the team was able to show that ants disinfect themselves on the inside. "When the ants were able to access the acid, their chances of survival increased significantly after eating food enriched with pathogenic bacteria," explains Tragust. What's more, the beneficial effect was not limited to an individual animal. Ants pass food from their mouth to the mouths to their nest mates. "This is a major potential source of infection," says Tragust. If the ant passing on the food has previously ingested the acid, the receiving ant had a lower risk of falling ill. According to Tragust, this behaviour might reduce the spread of infection within the ant colony.

The results of the new study also explain why some ants have very few bacteria in their digestive tracts; those that are present are primarily acid-resistant microbes. "Acid swallowing acts as a filter mechanism, structuring the ant's microbiome," explains Tragust. Ants are one of just a handful of animals with extremely acidic stomachs. "Otherwise this is only known to occur in humans and a few other vertebrates," says Tragust. Unlike ants, stomach acid in humans is produced directly in the stomach, but the effects are the same: The acid kills germs in the food and influences the microbiome of the gut.

Incidentally, how formic acid precisely works is still a mystery, but it and other organic acids have long been used as additives in animal feed to kill harmful germs.
Study: Tragust S. et al. Formicine ants swallow their highly acidic poison for gut microbial selection and control. eLife (2020). doi: 10.7554/eLife.60287

Martin-Luther-Universität Halle-Wittenberg

Related Bacteria Articles from Brightsurf:

Siblings can also differ from one another in bacteria
A research team from the University of Tübingen and the German Center for Infection Research (DZIF) is investigating how pathogens influence the immune response of their host with genetic variation.

How bacteria fertilize soya
Soya and clover have their very own fertiliser factories in their roots, where bacteria manufacture ammonium, which is crucial for plant growth.

Bacteria might help other bacteria to tolerate antibiotics better
A new paper by the Dynamical Systems Biology lab at UPF shows that the response by bacteria to antibiotics may depend on other species of bacteria they live with, in such a way that some bacteria may make others more tolerant to antibiotics.

Two-faced bacteria
The gut microbiome, which is a collection of numerous beneficial bacteria species, is key to our overall well-being and good health.

Microcensus in bacteria
Bacillus subtilis can determine proportions of different groups within a mixed population.

Right beneath the skin we all have the same bacteria
In the dermis skin layer, the same bacteria are found across age and gender.

Bacteria must be 'stressed out' to divide
Bacterial cell division is controlled by both enzymatic activity and mechanical forces, which work together to control its timing and location, a new study from EPFL finds.

How bees live with bacteria
More than 90 percent of all bee species are not organized in colonies, but fight their way through life alone.

The bacteria building your baby
Australian researchers have laid to rest a longstanding controversy: is the womb sterile?

Hopping bacteria
Scientists have long known that key models of bacterial movement in real-world conditions are flawed.

Read More: Bacteria News and Bacteria Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to