Rheumatologists win $1.2M for arthritis research

November 05, 2007

BIRMINGHAM, Ala. - Three researchers from the University of Alabama at Birmingham (UAB) have been awarded a combined $1.2 million to study the underlying causes of rheumatoid arthritis and to help find a cure for the disease.

The grants were among 15 awards nationwide made through the American College of Rheumatology (ACR) Research and Education Foundation.

The funds will be used by UAB experts to explore more deeply the molecular development of rheumatoid arthritis with the hope of finding new medicines and drug targets that slow or halt the disease. Another feature of UAB's research will be to identify hereditary and biological differences between some arthritis patients, and whether genetic markers could improve diagnosis and treatment of the disease.

Three physicians working in the UAB Division of Clinical Immunology and Rheumatology each were awarded $400,000. Robert H. Carter, M.D., and John Mountz, M.D., won grants in the innovative basic research category; S. Louis Bridges, M.D., won a grant in the translational research category.

"One of the strengths of these studies is being able take the strides that have been made in the treatment and management of rheumatoid arthritis, and build on that knowledge as we continue working toward better treatments and curative care," said Carter, director of the Division of Clinical Immunology and Rheumatology.

The three projects that earned ACR funding are: These studies will benefit rheumatoid arthritis patients and their families directly since they will draw upon volunteer participants, especially those who live in Alabama and throughout the Southeast. Rheumatoid arthritis affects more than one in every 200 Americans.

Carter said the world-renowned basic research taking place at UAB is one of the main reasons the trio of physicians were selected among an elite group nationally for the arthritis grants. UAB's rheumatology and immunology laboratories are equipped to accelerate new innovations into the testing and patient-care setting to help fight rheumatoid arthritis, he said.
-end-
The ACR Research and Education Foundation funding is part of the association's new "Within Our Reach: Finding a Cure for Rheumatoid Arthritis" campaign. The UAB awards were part of a larger grant announcement for projects totaling $6 million.

University of Alabama at Birmingham

Related Rheumatoid Arthritis Articles from Brightsurf:

Reducing dementia in patients with rheumatoid arthritis
The incidence of dementia in patients with rheumatoid arthritis is lower in patients receiving biologic or targeted synthetic disease modifying antirheumatic drugs (DMARDs) than in patients who receive conventional synthetic DMARDs, according to a new study.

Is rheumatoid arthritis two different diseases?
While disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with autoantibodies, according to a new study published this week in PLOS Medicine by Xanthe Matthijssen of Leiden University Medical Center, Netherlands, and colleagues.

Does the Mediterranean diet protect against rheumatoid arthritis?
Previous research has demonstrated a variety of health benefits associated with the Mediterranean diet, which is rich in olive oil, cereals, fruit and vegetables, fish, and a moderate amount of dairy, meat, and wine.

Reducing corticosteroid use in rheumatoid arthritis
Is the long-term use of glucocorticoids essential in people with chronic inflammatory diseases such as rheumatoid arthritis, or can early discontinuation prevent characteristic side effects?

Rheumatoid arthritis patients under treatment with methotrexate
Patients with rheumatoid arthritis (RA) often suffer from what is referred to as interstitial lung disease (ILD).

Rheumatoid arthritis -- can its onset be delayed or prevented?
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder that leads to significant health issues as well as high treatment costs.

Disease burden in osteoarthritis is similar to rheumatoid arthritis
Osteoarthritis (OA) has traditionally been viewed as a highly prevalent but milder condition when compared with rheumatoid arthritis (RA), and some may believe that it is part of a normal aging process requiring acceptance, not treatment.

Prospect of a new treatment for rheumatoid arthritis
An international research group led by Charité -- Universitätsmedizin Berlin has completed testing a new drug to treat rheumatoid arthritis.

Can rare lymphocytes combat rheumatoid arthritis?
Immunologists at Friedrich-Alexander-Universität Erlangen-Nürnberg have demonstrated that ILC2, a group of rare lymphoid cells, play a key role in the development of inflammatory arthritis.

Rheumatoid arthritis meets precision medicine
Scientists are bringing precision medicine to rheumatoid arthritis for the first time by using genetic profiling of joint tissue to see which drugs will work for which patients, reports a new multi-site study.

Read More: Rheumatoid Arthritis News and Rheumatoid Arthritis Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.