Analysis reveals high burden of musculoskeletal disorders across the globe

November 05, 2020

Musculoskeletal disorders--which affect muscles, tendons, ligaments, bones, and joints--can severely affect individuals' physical and mental health, and they're especially prevalent among aging adults. Although many researchers are studying these conditions and their rates in different regions of the world, no study to date has provided an overview of the burden of all musculoskeletal disorders. Investigators have now done so in Arthritis & Rheumatology, an official journal of the American College of Rheumatology.

For the analysis, researchers examined data from the Global Burden of Disease Study 2017, which assessed the extent of diseases and injuries across 21 regions and 195 countries and territories from 1990 to 2017. Musculoskeletal disorders included rheumatoid arthritis, osteoarthritis, low back pain, neck pain, gout, and related conditions.

The team found that there were approximately 1.3 billion prevalent cases and 121,300 deaths due to musculoskeletal disorders in 2017, as wells as 138.7 million disability-adjusted life years, or the number of years lost due to ill-health, disability, or early death. The burden of these diseases generally increased with age for both sexes, was more prevalent among females, and was higher in developed countries.

"Our study describes the enormous global burden of disability from musculoskeletal conditions in a single paper," said senior author Rachelle Buchbinder, MD, of the Cabrini Institute and Monash University, in Australia. "These conditions are under-recognized despite their enormous costs to individuals, the economy, and the health system. Also, there has been a lack of any significant decline in the burden from these conditions over time, which means that there is still insufficient emphasis on addressing the problem."

Dr. Buchbinder noted that policy makers must be made aware of the size of this growing problem, especially in light of rapidly aging populations around the world. "A global response is needed, and this should be integrated with other strategies that can address some of the modifiable and important risk factors of musculoskeletal disorders, including obesity, poor nutrition, smoking, and sedentary lifestyles," she said. "As well, there should be an emphasis on reducing low-value care for some of the most burdensome conditions such as low back pain and osteoarthritis that is contributing to the problem."

The authors also stressed the need for standardized methods for collecting data on the prevalence and impact of musculoskeletal disorders across the world.
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Full Citation: "Prevalence deaths and disability adjusted life years (DALYs) due to musculoskeletal disorders for 195 countries and territories 1990-2017." Saeid Safiri, Ali-Asghar Kolahi, Marita Cross, Catherine Hill, Emma Smith, Kristin Carson-Chahhoud, Mohammad Ali Mansournia, Amir Almasi-Hashiani, Ahad Ashrafi-Asgarabad, Jay Kaufman, Mahdi Sepidarkish, Seyed Kazem Shakouri, Damian Hoy, Anthony D. Woolf, Lyn March, Gary Collins, and Rachelle Buchbinder, MD. Arthritis & Rheumatology; Published Online: November 5, 2020. (DOI: 10.1002/art.41571).

URL Upon Publication:http://doi.wiley.com/10.1002/art.41571

Disclosures: The GBD 2017 Study was funded by Bill and Melinda Gates Foundation; however, the organization was not involved in any way in the preparation of the Arthritis & Rheumatology article. The report was supported by Shahid Beheshti University of Medical Sciences, Tehran, Iran (grant No 21740-4-7). Rachelle Buchbinder is supported by an Australian National Health and Medical Research Council (NHMRC) Senior Principal Research Fellowship. Marita Cross is supported by the Institute of Bone and Joint Research and the Global Alliance for Musculoskeletal Health.

Author Contact:media@monash.edu or +61 3 9903 4840

About the Journal

Arthritis & Rheumatology is an official journal of the American College of Rheumatology (ACR) and covers all aspects of inflammatory disease. The American College of Rheumatology (http://www.rheumatology.org) is the professional organization whose members share a dedication to healing, preventing disability, and curing the more than 100 types of arthritis and related disabling and sometimes fatal disorders of the joints, muscles, and bones. Members include practicing physicians, research scientists, nurses, physical and occupational therapists, psychologists, and social workers. The journal is published by Wiley on behalf of the ACR. For more information, please visit http://wileyonlinelibrary.com/journal/art.

About Wiley

Wiley drives the world forward with research and education. Through publishing, platforms and services, we help students, researchers, universities, and corporations to achieve their goals in an ever-changing world. For more than 200 years, we have delivered consistent performance to all of our stakeholders. The Company's website can be accessed at http://www.wiley.com.

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