Doctors able to predict chance of breast cancer returning

November 06, 2006

Doctors have created a first-ever computer tool to predict the risk of breast cancer returning in the same breast over a 10-year period in women who have had breast conserving surgery to remove only the cancer (lumpectomy), according to a study presented November 6, 2006, at the American Society for Therapeutic Radiology and Oncology's 48th Annual Meeting in Philadelphia.

"Our tool provides physicians with information regarding the risk of breast cancer returning in the same breast for any individual patient, which can then help them evaluate the potential benefit of additional treatments needed to cure the cancer, including radiation therapy," said Mona Sanghani, M.D., lead author of the study and an oncologist at Tufts-New England Medical Center in Boston. "This predictive tool, however, must be validated by independent clinical data before it is widely used."

For patients with early stage breast cancer, the current standard treatment involves breast conserving surgery followed by radiation therapy to the breast over a six to eight week period to kill any remaining cancer cells.

Researchers developed a formula that takes into account all of the risk factors associated with breast cancer coming back in the same breast after breast conserving surgery, such as the age of the patient at the time of treatment, the size and grade of the cancer, if lymphatic vessels are affected, and the use of chemotherapy or hormone therapy. With the help of a Web-based computer tool, doctors are able to determine by this formula how much a patient will be at risk for their cancer returning, along with how much a patient will benefit from radiation therapy.
-end-
For more information on radiation therapy for breast cancer, visit www.rtanswers.org.

The abstract, "Predicting the Risk of Local Recurrence in Patients with Breast Cancer: An Approach to a New Computer Based Predictive Tool," will be presented in a scientific session on Monday, November 6, at 11:25 a.m. To speak to the lead author of the study, Mona Sanghani, M.D., please call Beth Bukata or Julie Moore November 5-8 in the ASTRO Press Room at the Pennsylvania Convention Center at 215-418-2257 or 215-418-2258. You may also e-mail Julie at juliem@astro.org.

ASTRO is the largest radiation oncology society in the world, with more than 8,500 members who specialize in treating patients with radiation therapies. As the leading organization in radiation oncology, biology and physics, the Society is dedicated to the advancement of the practice of radiation oncology by promoting excellence in patient care, providing opportunities for educational and professional development, promoting research and disseminating research results and representing radiation oncology in a rapidly evolving socioeconomic healthcare environment.

American Society for Radiation Oncology

Related Cancer Articles from Brightsurf:

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications.

UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies
A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.

Breast cancer treatment costs highest among young women with metastic cancer
In a fight for their lives, young women, age 18-44, spend double the amount of older women to survive metastatic breast cancer, according to a large statewide study by the University of North Carolina at Chapel Hill.

Cancer mortality continues steady decline, driven by progress against lung cancer
The cancer death rate declined by 29% from 1991 to 2017, including a 2.2% drop from 2016 to 2017, the largest single-year drop in cancer mortality ever reported.

Stress in cervical cancer patients associated with higher risk of cancer-specific mortality
Psychological stress was associated with a higher risk of cancer-specific mortality in women diagnosed with cervical cancer.

Cancer-sniffing dogs 97% accurate in identifying lung cancer, according to study in JAOA
The next step will be to further fractionate the samples based on chemical and physical properties, presenting them back to the dogs until the specific biomarkers for each cancer are identified.

Moffitt Cancer Center researchers identify one way T cell function may fail in cancer
Moffitt Cancer Center researchers have discovered a mechanism by which one type of immune cell, CD8+ T cells, can become dysfunctional, impeding its ability to seek and kill cancer cells.

More cancer survivors, fewer cancer specialists point to challenge in meeting care needs
An aging population, a growing number of cancer survivors, and a projected shortage of cancer care providers will result in a challenge in delivering the care for cancer survivors in the United States if systemic changes are not made.

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment.

American Cancer Society outlines blueprint for cancer control in the 21st century
The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that forms the basis of a national cancer control plan.

Read More: Cancer News and Cancer Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.