NTP-CERHR announces the Second Phthalates Expert Panel Meeting to be held December 15-17, 1999

November 08, 1999

NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) will hold the second meeting of an Expert Panel to evaluate seven phthalate esters -- or plasticizers-- December 15-17, 1999 at the Hawthorn Suites (Research Triangle Park), 300 Meredith Drive, Durham, North Carolina 27713. The meeting will convene 8:30 a.m., Wednesday, December 15 and will end at approximately 3 p.m. on December 17.

The purpose of the meeting is to complete the integrated evaluation documents that were begun during the meeting held August 17-19, 1999 in Alexandria, Virginia and to draft summary statements on the seven phthalate esters. The seven phthalates being reviewed are butyl benzyl phthalate, di(2-ethylhexyl) phthalate, di-isodecyl phthalate, di-isononyl phthalate, di-n-butyl phthalate, di-n-hexyl phthalate, and di-n-octyl phthalate. At the completion of the first meeting, integrated evaluation documents were drafted and reviewed by the full Panel for the following 3 phthalates: butyl benzyl phthalate, di(2-ethylhexyl)phthalate, and di-n-octyl phthalate. These previously written integrated evaluations and the four new ones (di-isodecyl phthalate, di-isononyl phthalate, di-n-butyl phthalate, and di-n-hexyl phthalate) will be discussed at the Expert Panel meeting being held December 15-17. Following agreement on the integrated evaluations, summary statements reflecting significant conclusions and judgements for each of the phthalates will be developed and agreed to by the entire Panel. These narrative statements will reflect a consensus opinion of the Panel as to the developmental and reproductive toxicity of these chemicals in experimental models and will address the potential significance of these results to human reproduction and development.

The Phthalate Panel Members are: Robert Kavlock, PhD (Chair) EPA/ORD; Kim Boekelheide, MD, PhD, Brown University; Robert Chapin, PhD, NIEHS; Michael Cunningham, PhD, NIEHS; Elaine Faustman, PhD, University of Washington; Paul Foster, PhD, Chemical Industry Institute of Toxicology; Mari Golub, PhD, Cal/EPA; Rogene Henderson, PhD, Inhalation Toxicology Research Institute; Irwin Hinberg, PhD, Health Canada; Ruth Little, ScD, NIEHS; Jennifer Seed, PhD, EPA/OPPT; Katherine Shea, MD, University of North Carolina; Rochelle Tyl, PhD, Research Triangle Institute; Paige Williams, PhD, Harvard University; and Timothy Zacharewski, PhD, Michigan State University.

The review will be open to the public and time will be available for public comment. For registration information, please contact: Ms. Peggy Sheren, CERHR, 1800 Diagonal Road, Suite 500, Alexandria, VA 22314-2808, Phone: (703) 838-9440.

NIH/National Institute of Environmental Health Sciences

Related Phthalates Articles from Brightsurf:

Researchers find connection between household chemicals and gut microbiome
A team of researchers for the first time has found a correlation between the levels of bacteria and fungi in the gastrointestinal tract of children and the amount of common chemicals found in their home environment.

A better alternative to Phthalates?
In collaboration with the Medical University of South Carolina, researchers at the National Institute of Standards and Technology (NIST) analyzed urine samples from pregnant women to look for the presence of DINCH, which is short for di(isononyl)cyclohexane-1,2-dicarboxylate.

Exposure to environmental chemicals may disrupt sleep during menopause
For menopausal women who have difficulty sleeping, it might be because of chemicals in the environment.

Environmental contaminants alter gut microbiome, health
The microbes that inhabit our bodies are influenced by what we eat, drink, breathe and absorb through our skin, and most of us are chronically exposed to natural and human-made environmental contaminants.

Prenatal phthalate exposure associated with autistic traits in young boys
Exposure in the womb to phthalates, a group of endocrine-disrupting chemicals present in cosmetics and other common household products, was associated with autistic traits in boys, ages 3 and 4, but not in girls, according to a new study led by a University of Massachusetts Amherst environmental epidemiologist.

Break point
Experiments in worms reveal the molecular damage caused by DEHP, a chemical commonly used to make plastics flexible.

Plasticizers may contribute to motor control problems in girls
Scientists at the Columbia Center for Children's Environmental Health (CCCEH) have uncovered a link between prenatal exposure to phthalates--a ubiquitous group of plasticizers and odor-enhancing chemicals--and deficits in motor function in girls.

Stress, plastic additives in late pregnancy raise risk of premature birth
Women exposed simultaneously to stress and plastic additives late in pregnancy are at increased risk for premature birth, according to a study by Rutgers and other institutions.

Bisphenol-a structural analogues may be less likely than BPA to disrupt heart rhythm
Some chemical alternatives to plastic bisphenol-a (BPA), which is still commonly used in medical settings such as operating rooms and intensive care units, may be less disruptive to heart electrical function than BPA, according to a pre-clinical study that explored how the structural analogues bisphenol-s (BPS) and bisphenol-f (BPF) interact with the chemical and electrical functions of heart cells.

Genetic inequity towards endocrine disruptors
Phthalates are used by industry in plastic products. Their toxic effect on the endocrine system is worrying.

Read More: Phthalates News and Phthalates Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.