Tips from the Journals of the American Society for Microbiology

November 11, 2002

Household disinfectant potential cause of antibiotic resistance

Researchers from Midwestern University in Illinois, Curtin University of Technology in Australia, and Illinois State University have found that when bacteria become resistant to pine oil cleaners (POC), a common household disinfectant, they may also be resistant to some antibiotics. Their findings appear in the November 2002 issue of Applied and Environmental Microbiology.

In the study, POC-resistant Staphylococcus aureus were found to also be resistant to the antibiotics, vancomycin and oxacillin. Further testing suggests that the same genetic mechanism may be responsible for both types of resistance.

"These results add to a growing body of reports suggesting that common disinfectants can select for bacteria with reduced susceptibilities to antibiotics," say the researchers.

(C.T.D. Price, V.K. Singh, R.K. Jayaswal, B.J. Wilkinson, J.E. Gustafson. 2002. Pine oil cleaner-resistant staphylococcus aureus: reduced susceptibility to vancomycin and oxacillin and involvement of SigB. Applied and Environmental Microbiology, 68. 11: 5417-5421.)

Bacterial infection possible cause of liver disease

A bacterial infection could be responsible for some cases of chronic liver disease, say researchers from Estonia and Sweden in the November 2002 issue of the journal Clinical and Diagnostic Laboratory Immunology.

In the study, researchers compared levels of antibodies against Helicobacter bacteria (the acid tolerant family of bacteria responsible for most peptic ulcers) in patients with chronic liver disease to a random sample from the general public. The patients with liver disease had significantly higher antibodies to at least two species of Helicobacter bacteria.

"Bile-tolerant Helicobacter species such as Helicobacter pullorum, Helicobacter bilis, and Helicobacter hepaticus are associated with hepatic disorders in animals and may be involved in the pathogenesis of chronic liver diseases in humans," say the researchers.

(O. Ananieva, I. Nilsson, T. Vorobjova, R. Uibo and T. Wadstrom. 2002. Immune responses to bile-tolerant Helicobacter species in patients with chronic liver diseases, a randomized population group, and healthy blood donors. Clinical and Diagnostic Laboratory Immunology, 9: 1160-1164.)

Existing antiviral potential treatment for smallpox

A drug currently licensed for treatment of an opportunistic infection in AIDS patients may be an effective treatment against smallpox, say researchers from the Rega Institute for Medical Research in Belgium and the Academy of Sciences of the Czech Republic. Their findings appear in the November 2002 issue of the journal Antimicrobial Agents and Chemotherapy.

In the study, the researchers tested the effectiveness of a variety of drugs on their ability to prevent replication of vaccinia virus, a distant relative of smallpox that is used in the current smallpox vaccine. One antiviral drug, cidofovir, that has already been approved for other treatments, appeared to be highly active against poxvirus infection.

"Cidofovir, which is on the market for treatment of human cytomegalovirus retinitis in immunocompromised patients, is potentially a good candidate for the treatment of a poxvirus outbreak, in the absence of any vaccination," say the researchers.

(R. Snoeck, A. Holy, C. Dewolf-peeters, J. Van Den Oord, E. De Clercq, and G. Andrei. 2002. Antivaccinia activities of acyclic nucleoside phosphonate derivatives in epithelial cells and organotypic cultures. Antimicrobial Agents and Chemotherapy, 46: 3356-3361.)

American Society for Microbiology

Related Bacteria Articles from Brightsurf:

Siblings can also differ from one another in bacteria
A research team from the University of Tübingen and the German Center for Infection Research (DZIF) is investigating how pathogens influence the immune response of their host with genetic variation.

How bacteria fertilize soya
Soya and clover have their very own fertiliser factories in their roots, where bacteria manufacture ammonium, which is crucial for plant growth.

Bacteria might help other bacteria to tolerate antibiotics better
A new paper by the Dynamical Systems Biology lab at UPF shows that the response by bacteria to antibiotics may depend on other species of bacteria they live with, in such a way that some bacteria may make others more tolerant to antibiotics.

Two-faced bacteria
The gut microbiome, which is a collection of numerous beneficial bacteria species, is key to our overall well-being and good health.

Microcensus in bacteria
Bacillus subtilis can determine proportions of different groups within a mixed population.

Right beneath the skin we all have the same bacteria
In the dermis skin layer, the same bacteria are found across age and gender.

Bacteria must be 'stressed out' to divide
Bacterial cell division is controlled by both enzymatic activity and mechanical forces, which work together to control its timing and location, a new study from EPFL finds.

How bees live with bacteria
More than 90 percent of all bee species are not organized in colonies, but fight their way through life alone.

The bacteria building your baby
Australian researchers have laid to rest a longstanding controversy: is the womb sterile?

Hopping bacteria
Scientists have long known that key models of bacterial movement in real-world conditions are flawed.

Read More: Bacteria News and Bacteria Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to