HIV, diagnostic health care tools top of list for UH researchers

November 15, 2004

HOUSTON, Nov. 15, 2004 - Designing devices to combat HIV and biosensors to aid in diagnostic health care will be among the presentations of two University of Houston professors at a gathering of the top nanotechnologists in the nation Nov. 19-21.

The National Academies Keck Futures Initiative conference - "Designing Nanostructures at the Interface Between Biomedical and Physical Systems" - will bring together approximately 100 of the nation's top researchers to discuss the emerging science of nanotechnology Nov. 19-21 at the Arnold and Mabel Beckman Center in Irvine, Calif. Kurt Krause, associate professor of biology and biochemistry at UH, and Rigoberto Advincula, associate professor of chemistry at UH, are two of only 12 researchers from the Gulf Coast area invited to attend the conference.

"The organizers of the Futures Initiative were particularly interested in my background on modifying surfaces with polyelectrolytes and dendrimers for the controlled adsorption and capture of DNA and proteins," Advincula said. "We are looking at applying these methods for microfluidic devices and biosensors."

Coming a long way from applications in such mundane gadgets as ink-jet printers, microfluidic devices - one of Advincula's specialties - now hold potential for pharmaceuticals, biotechnology, defense, public health and agriculture. This next generation of applications shows the flexibility of these devices that will be crucial to their commercial viability. Another of Advincula's research projects involves biosensors that can detect toxins and bacteria in an environment, ultimately leading to uses in diagnostic health care and biological/chemical detection.

Presenting some of his latest breakthroughs in the fight against HIV, Krause will present research on the design of proteins that can split DNA made by pathogenic organisms, which will produce nanomachines that could be used to combat latent infections caused by viruses like HIV. He also will join a focus group exploring energy production from biological nanosystems that could eventually lead to cleaner, more efficient energy supplies, reducing both costs and environmental consequences. Full details of these focus groups and research presentations will be available online, following the conclusion of the conference.
-end-
Funded by a $40 million grant from the W.M. Keck Foundation, the National Academies Keck Futures Initiatives is a 15-year effort to catalyze interdisciplinary inquiry and to enhance communication among researchers, funding agencies, universities and the general public. Representing science, engineering and medical disciplines, conference attendees convene with the common mission to explore questions related to nanotechnology and nanoscience. Working on matter that is 100,000 times smaller than the width of a human hair, the practice of nanotechnology manipulates individual molecules and atoms. Seed grants will be awarded to selected researchers who attend. For more information, visit www7.nationalacademies.org/keck/keck_futures_conferences.html.

About the University of Houston
The University of Houston, Texas' premier metropolitan research and teaching institution, is home to more than 40 research centers and institutes and sponsors more than 300 partnerships with corporate, civic and governmental entities. UH, the most diverse research university in the country, stands at the forefront of education, research and service with more than 35,000 students.

For more information about UH, visit the university's Newsroom at www.uh.edu/newsroom

To receive UH science news via e-mail, visit www.uh.edu/admin/media/sciencelist.html

University of Houston

Related HIV Articles from Brightsurf:

BEAT-HIV Delaney collaboratory issues recommendations measuring persistent HIV reservoirs
Spearheaded by Wistar scientists, top worldwide HIV researchers from the BEAT-HIV Martin Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy (BEAT-HIV Collaboratory) compiled the first comprehensive set of recommendations on how to best measure the size of persistent HIV reservoirs during cure-directed clinical studies.

The Lancet HIV: Study suggests a second patient has been cured of HIV
A study of the second HIV patient to undergo successful stem cell transplantation from donors with a HIV-resistant gene, finds that there was no active viral infection in the patient's blood 30 months after they stopped anti-retroviral therapy, according to a case report published in The Lancet HIV journal and presented at CROI (Conference on Retroviruses and Opportunistic Infections).

Children with HIV score below HIV-negative peers in cognitive, motor function tests
Children who acquired HIV in utero or during birth or breastfeeding did not perform as well as their peers who do not have HIV on tests measuring cognitive ability, motor function and attention, according to a report published online today in Clinical Infectious Diseases.

Efforts to end the HIV epidemic must not ignore people already living with HIV
Efforts to prevent new HIV transmissions in the US must be accompanied by addressing HIV-associated comorbidities to improve the health of people already living with HIV, NIH experts assert in the third of a series of JAMA commentaries.

The Lancet HIV: Severe anti-LGBT legislations associated with lower testing and awareness of HIV in African countries
This first systematic review to investigate HIV testing, treatment and viral suppression in men who have sex with men in Africa finds that among the most recent studies (conducted after 2011) only half of men have been tested for HIV in the past 12 months.

The Lancet HIV: Tenfold increase in number of adolescents on HIV treatment in South Africa since 2010, but many still untreated
A new study of more than 700,000 one to 19-year olds being treated for HIV infection suggests a ten-fold increase in the number of adolescents aged 15 to 19 receiving HIV treatment in South Africa, according to results published in The Lancet HIV journal.

Starting HIV treatment in ERs may be key to ending HIV spread worldwide
In a follow-up study conducted in South Africa, Johns Hopkins Medicine researchers say they have evidence that hospital emergency departments (EDs) worldwide may be key strategic settings for curbing the spread of HIV infections in hard-to-reach populations if the EDs jump-start treatment and case management as well as diagnosis of the disease.

NIH HIV experts prioritize research to achieve sustained ART-free HIV remission
Achieving sustained remission of HIV without life-long antiretroviral therapy (ART) is a top HIV research priority, according to a new commentary in JAMA by experts at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

The Lancet HIV: PrEP implementation is associated with a rapid decline in new HIV infections
Study from Australia is the first to evaluate a population-level roll-out of pre-exposure prophylaxis (PrEP) in men who have sex with men.

Researchers date 'hibernating' HIV strains, advancing BC's leadership in HIV cure research
Researchers have developed a novel way for dating 'hibernating' HIV strains, in an advancement for HIV cure research.

Read More: HIV News and HIV Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.