Air pollution associated with higher rates of chronic kidney disease

November 15, 2014

Philadelphia, PA (November 15, 2014) -- Air pollution may play a role in the development of kidney disease, according to a study that will be presented at ASN Kidney Week 2014 November 11¬-16 at the Pennsylvania Convention Center in Philadelphia, PA.

There are wide variances in the prevalence of chronic kidney disease (CKD) across the United States, only part of which is explained by differences in individuals' risk factors. To see if air quality may also play a role, Jennifer Bragg-Gresham, PhD (University of Michigan) and her colleagues looked at 2010 Medicare information on 1.1 million persons as well as air-quality data for all US counties provide by the Environmental Protection Agency.

The investigators found a link between the prevalence of CKD and the county level of particulate matter, even after taking into account patient risk factors for CKD including age, diabetes, and hypertension. An elevated prevalence of CKD was observed when particulate matter levels were as low as 8.4 μg/m3, which is much lower than levels typically considered unhealthy for sensitive groups such as the elderly (~40 μg/m3).

"If air pollution is a risk factor for CKD, the impact is likely to be even greater in countries where pollution levels are much higher than in the U.S. Future investigations should include lab-based diagnosis of CKD, longitudinal data, measures of multiple air pollutants and individual exposure, and more extensive control of confounding factors," said Dr. Bragg-Gresham.
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Study: "County-level Air Quality and the Prevalence of Diagnosed Chronic Kidney Disease in the U.S. Medicare Population" (Abstract SA-PO802)

Disclosure information is available at http://www.asn-online.org/education/kidneyweek/2014/program-faculty.aspx.

ASN Kidney Week 2014, the largest nephrology meeting of its kind, will provide a forum for more than 13,000 professionals to discuss the latest findings in renal research and engage in educational sessions related to advances in the care of patients with kidney and related disorders. Kidney Week 2014 will take place November 11-16, 2014, in Philadelphia, PA.

The content of this article does not reflect the views or opinions of The American Society of Nephrology (ASN). Responsibility for the information and views expressed therein lies entirely with the author(s). ASN does not offer medical advice. All content in ASN publications is for informational purposes only, and is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This content should not be used during a medical emergency or for the diagnosis or treatment of any medical condition. Please consult your doctor or other qualified health care provider if you have any questions about a medical condition, or before taking any drug, changing your diet or commencing or discontinuing any course of treatment. Do not ignore or delay obtaining professional medical advice because of information accessed through ASN. Call 911 or your doctor for all medical emergencies.

Founded in 1966, and with more than 15,000 members, the American Society of Nephrology (ASN) leads the fight against kidney disease by educating health professionals, sharing new knowledge, advancing research, and advocating the highest quality care for patients.

American Society of Nephrology

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