Research finds Zika virus can live for hours on hard, non-porous surfaces

November 15, 2016

DENVER (Nov. 15, 2016) -- The Zika virus is most commonly transmitted in humans as the result of a bite from an infected mosquito or from an infected human to another human. What is not well known is that the virus also can be transmitted via the environment if an individual is pricked with an infected needle or has an open cut and comes in contact with the live virus. While there are no known cases to date of the general public being infected with the Zika virus through the environment, there has been at least one documented case of laboratory acquired Zika virus infection.

Research being presented today at the 2016 American Association of Pharmaceutical Scientist (AAPS) Annual Meeting and Exposition, which is taking place Nov. 13 -17 in Denver, found that under certain conditions, the Zika virus can live for several hours on hard non-porous surfaces and still be highly contagious, but that some commonly used disinfectants are extremely effective in killing the virus. The research may have important infection control implications for both consumers and those who work in healthcare or lab settings.

The study looked at isopropyl alcohol, diluted bleach, quaternary ammonium/alcohol, peracetic acid, and pH 4 or pH 10 solutions, which are commonly used in clinical, laboratory and industrial settings.

Findings showed that when the virus was in an environment without blood, these methods of inactivating Zika, except pH 4 and pH 10, were largely effective, but in environments where virus was associated with blood, the results were dramatically different.

"Zika can survive on hard, non-porous surfaces for as long as eight hours, possibly longer when the environment contains blood, which is more likely to occur in the real world," said the study's lead researcher S. Steve Zhou, Ph.D. "The good news is that we found that disinfectants such as isopropyl alcohol and quaternary ammonium/alcohol are generally effective in killing the virus in this type of environment and can do so in a little as 15 seconds."

Zhou, who is the director of virology and molecular biology for Microbac Laboratories, headquartered in Pittsburgh, Penn., said the study did not yet look at the survivability of Zika on hard non-porous surfaces beyond eight hours.

Microbac's research also found that bleach and peracetic acid were not as effective in killing Zika virus when the virus is associated with blood.

"The data were important to know especially for healthcare providers and researchers," said Zhou. "One must bear the organic load of the environment such as blood, in mind, before reaching a conclusion about the Zika virus inactivation efficacy by a particular product."

The next stage of the research will be to take a more in-depth look at how long Zika survives on hard non-porous surfaces in the heat and how best to inactivate the virus.
-end-
18T0200 - Inactivation of Zika Virus on a Hard Non-porous Surface will be presented on Tuesday, Nov. 15 from 2:00 - 2:30 p.m. in the Colorado Convention Center - Exhibit Hall E by co-author, Ray Nims, Ph.D. of RMC Pharmaceutical Solutions, Inc.

The 2016 AAPS Annual Meeting and Exposition aims to improve global health through advances in pharmaceutical sciences, and there will be over 700 exhibitor booths and an estimated 6,500 attendees. The meeting features nearly 245 programming sessions, including more than 65 symposia and roundtables and more than 1,900 posters. Download the AAPS mobile application for additional information.

Editor's Note: All media must provide press credentials to attend this meeting and register onsite at the Colorado Convention Center in the press room 105. To schedule an interview with Steve Zhou, or for any other press inquiries, please contact Katie Baumer at baumerk@aaps.org or 703-248-4772 or Hillarie Turner at hillarie@vaneperen.com or 301-836-1516 x7. For the most up-to-date program information, please click here.

About AAPS: The American Association of Pharmaceutical Scientists (AAPS) is a professional, scientific organization of approximately 9,000 members employed in academia, industry, government, and other research institutes worldwide. Founded in 1986, AAPS advances the capacity of pharmaceutical scientists to develop products and therapies that improve global health. Visit http://www.aaps.org and follow us on Facebook and Twitter @AAPSComms. The official Twitter hashtag for the meeting is: #AAPS2016.

American Association of Pharmaceutical Scientists

Related Zika Virus Articles from Brightsurf:

'Domestication' increases mosquito's zika virus susceptibility
The Aedes aegypti aegypti subspecies of mosquito, which has become a ''domestic'' pest worldwide, can acquire and transmit Zika virus more easily than its African forerunner.

Greater mosquito susceptibility to Zika virus fueled the epidemic
By experimentally comparing wild populations of Ae. aegypti the researchers discovered that the invasive subspecies is very effective at transmitting the Zika virus not only because it has more frequent contacts with humans for blood meals, but also as a result of its greater susceptibility to the virus relative to the African subspecies.

Unravelling mother to baby transmission of Zika virus
Researchers have discovered that when a pregnant mother is infected by Zika virus, it can remain in the placenta for months, causing damage that can be dangerous to the fetus.

Consequences of Zika virus attack on glial cells
Few studies have identified the effects of zika virus infection on astrocytes, as well as their association with developmental alterations, including brain malformations and microcephaly.

Breakthrough in Zika virus vaccine
Researchers from the University of Adelaide have made significant advances in developing a novel vaccine against Zika virus, which could potentially lead to global elimination of the disease.

How the Zika virus can spread
The spread of infectious diseases such as Zika depends on many different factors.

Prior Zika virus or dengue virus infection does not affect secondary infections in monkeys
Previous infection with either Zika virus or dengue virus has no apparent effect on the clinical course of subsequent infection with the other virus, according to a study published August 1 in the open-access journal PLOS Pathogens by David O'Connor of the University of Wisconsin-Madison, and colleagues.

Early dengue virus infection could "defuse" zika virus
The Zika virus outbreak in Latin America has affected over 60 million people up to now.

Long-term consequences of Zika virus infection
Mice exposed to the Zika virus during later stages of gestation present behaviors reminiscent of attention-deficit/hyperactivity disorder, according to a study of genetically diverse animals.

Protection from Zika virus may lie in a protein derived from mosquitoes
By targeting a protein found in the saliva of mosquitoes that transmit Zika virus, Yale investigators reduced Zika infection in mice.

Read More: Zika Virus News and Zika Virus Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.