Artificial intelligence predicts treatment effectiveness

November 16, 2018

How can a doctor predict the treatment outcome of an individual patient? Traditionally, the effectiveness of medical treatments is studied by randomised trials where patients are randomly divided into two groups: one of the groups is given treatment, and the other a placebo. Is this really the only reliable way to evaluate treatment effectiveness, or could something be done differently? How can the effectiveness of a treatment method be evaluated in practice? Could some patients benefit from a treatment that does not cause a response in others?

A new method developed by Finnish researchers at the University of Eastern Finland, Kuopio University Hospital and Aalto University now provides answers to these questions. Using modelling, the method makes it possible to compare different treatment alternatives and to identify patients who will benefit from treatment. Relying on artificial intelligence, the method is based on causal Bayesian networks.

According to Professor Emeritus Olli-Pekka Ryynänen from the University of Eastern Finland, the method opens up new and significant avenues for the development of medical research.

"We can now predict the treatment outcome in individual patients and to evaluate existing and new treatment methods. With this method, it is also possible to replace some randomised trials with modelling," Professor Emeritus Ryynänen says.

In the newly published study, the researchers used the method to evaluate treatment effectiveness in obstructive sleep apnoea; however, the method can also be applied to other treatments. The study showed that in patients with sleep apnoea, the continuous positive airway pressure (CPAP) treatment reduced mortality and the occurrence of myocardial infarctions and cerebrovascular insults by five percent in the long term. For patients with heart conditions, CPAP was less beneficial.

The findings were reported in Healthcare Informatics Research.
-end-
For further information, please contact:

Professor Emeritus Olli-Pekka Ryynänen, University of Eastern Finland, tel. +358 40 5141741, olli-pekka.ryynanen (a) uef.fi

Research article:

Olli-Pekka Ryynänen, Timo Leppänen, Pekka Kekolahti, Esa Mervaala & Juha Töyräs. Bayesian Network Model to Evaluate the Effectiveness of Continuous Positive Airway Pressure Treatment of Sleep Apnea. Healthc Inform Res. 2018 Oct;24(4):346-358. Published online October 31, 2018. https://doi.org/10.4258/hir.2018.24.4.346

University of Eastern Finland

Related Artificial Intelligence Articles from Brightsurf:

Physics can assist with key challenges in artificial intelligence
Two challenges in the field of artificial intelligence have been solved by adopting a physical concept introduced a century ago to describe the formation of a magnet during a process of iron bulk cooling.

A survey on artificial intelligence in chest imaging of COVID-19
Announcing a new article publication for BIO Integration journal. In this review article the authors consider the application of artificial intelligence imaging analysis methods for COVID-19 clinical diagnosis.

Using artificial intelligence can improve pregnant women's health
Disorders such as congenital heart birth defects or macrosomia, gestational diabetes and preterm birth can be detected earlier when artificial intelligence is used.

Artificial intelligence (AI)-aided disease prediction
Artificial Intelligence (AI)-aided Disease Prediction https://doi.org/10.15212/bioi-2020-0017 Announcing a new article publication for BIO Integration journal.

Artificial intelligence dives into thousands of WW2 photographs
In a new international cross disciplinary study, researchers from Aarhus University, Denmark and Tampere University, Finland have used artificial intelligence to analyse large amounts of historical photos from WW2.

Applying artificial intelligence to science education
A new review published in the Journal of Research in Science Teaching highlights the potential of machine learning--a subset of artificial intelligence--in science education.

New roles for clinicians in the age of artificial intelligence
New Roles for Clinicians in the Age of Artificial Intelligence https://doi.org/10.15212/bioi-2020-0014 Announcing a new article publication for BIO Integration journal.

Artificial intelligence aids gene activation discovery
Scientists have long known that human genes are activated through instructions delivered by the precise order of our DNA.

Artificial intelligence recognizes deteriorating photoreceptors
A software based on artificial intelligence (AI), which was developed by researchers at the Eye Clinic of the University Hospital Bonn, Stanford University and University of Utah, enables the precise assessment of the progression of geographic atrophy (GA), a disease of the light sensitive retina caused by age-related macular degeneration (AMD).

Classifying galaxies with artificial intelligence
Astronomers have applied artificial intelligence (AI) to ultra-wide field-of-view images of the distant Universe captured by the Subaru Telescope, and have achieved a very high accuracy for finding and classifying spiral galaxies in those images.

Read More: Artificial Intelligence News and Artificial Intelligence Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.