Chest compression device outperforms manual CPR

November 19, 2002

A battery-operated compression belt buckled around the chest restores blood flow better than manual chest compressions and conventional CPR, according to a Johns Hopkins-led animal study.

The device, which resembles an eight-inch wide seat belt, is buckled around the chest, tightened and motorized. Once switched on, it contracts against the chest, stimulating blood flow.

Researchers who tested the device on 20 pigs in cardiac arrest found that it restored blood flow four times better than manual compressions and returned the hearts to pre-arrest condition. Results of the study, supported by Revivant Corp., are to be presented Nov. 19 at the American Heart Association's 75th annual Scientific Sessions in Chicago.

"The key to restoring viability is to wash out the waste and move oxygenated blood to the vital organs," says Henry R. Halperin, M.D., lead author of the study and professor of medicine and biomedical engineering at Hopkins. "The belt can compress a greater area of the chest than manual compressions, so it restores more blood flow than manual CPR. Wherever a health care professional would do manual CPR, a device like this could be better for the patient."

Researchers induced ventricular fibrillation, an electrical abnormality in the heart that precedes cardiac arrest, in the pigs. They then performed both manual cardiopulmonary resuscitation and CPR using the belt device, in random order, and measured blood pressure and flow before and after injecting the pigs with epinephrine, a hormone that constricts small blood vessels.

About 350,000 people each year suffer sudden cardiac arrest, 95 percent of whom die; most require defibrillation. Defibrillators are most effective if used within the first two minutes of arrest, Halperin says, but most attacks occur at home. It can take an average of six to eight minutes for paramedics to arrive, he says, and defibrillation is often unsuccessful at that time. At that point, generating more blood flow is the key to survival.

The device tested was Revivant's Autopulse. The study group is planning a clinical trial to evaluate the device's performance on humans. Other authors were Menekhem Zviman and Jennifer Johnson of Hopkins; Norman Paradis of the University of Colorado Health Science Center; Joseph P. Ornato of Virginia Commonwealth University Health System; and Karl B. Kern of the University of Arizona.

Halperin is a paid consultant of Revivant, holds stock in the company and is a member of the organization's scientific advisory board. These relationships are managed by The Johns Hopkins University in accordance with its conflict-of-interest policies.
-end-
Abstract #115668: Halperin, H.R. et al, "Improved Hemodynamics with a Novel Chest Compression Device in a Porcine Model of Cardiac Arrest"

Photos available at: http://www.hopkinsmedicine.org/press/2002/November/021114_AHA.htm

Related Web sites:

Johns Hopkins - Division of Cardiology http://www.hopkinsmedicine.org/cardiology/index.htm

American Heart Association http://www.americanheart.org

Media Contact: Karen Blum 410-955-1534 Email: kblum@jhmi.edu

Johns Hopkins Medical Institutions' news releases are available on an EMBARGOED basis on EurekAlert at http://www.eurekalert.org and from the Office of Communications and Public Affairs' direct e-mail news release service. To enroll, call 410-955-4288 or send e-mail to bsimpkins@jhmi.edu.

On a POST-EMBARGOED basis find them at http://www.hopkinsmedicine.org

Johns Hopkins Medicine

Related Blood Flow Articles from Brightsurf:

Brain regions with impaired blood flow have higher tau levels
In Alzheimer's disease, impaired blood flow to brain regions coincides with tau protein buildup.

3D ultrasound enables accurate, noninvasive measurements of blood flow
A 3D ultrasound system provides an effective, noninvasive way to estimate blood flow that retains its accuracy across different equipment, operators and facilities, according to a new study.

Blood flow recovers faster than brain in micro strokes
Work by a Rice neurobiologist shows that increased blood flow to the brain is not an accurate indicator of neuronal recovery after a microscopic stroke.

Exercise improves memory, boosts blood flow to brain
Scientists have collected plenty of evidence linking exercise to brain health, with some research suggesting fitness may even improve memory.

3D VR blood flow to improve cardiovascular care
Biomedical engineers are developing a massive fluid dynamics simulator that can model blood flow through the full human arterial system at subcellular resolution.

MRI shows blood flow differs in men and women
Healthy men and women have different blood flow characteristics in their hearts, according to a new study.

Brain blood flow sensor discovery could aid treatments for high blood pressure & dementia
A study led by researchers at UCL has discovered the mechanism that allows the brain to monitor its own blood supply, a finding in rats which may help to find new treatments for human conditions including hypertension (high blood pressure) and dementia.

Blood flow monitor could save lives
A tiny fibre-optic sensor has the potential to save lives in open heart surgery, and even during surgery on pre-term babies.

Changes in blood flow tell heart cells to regenerate
Altered blood flow resulting from heart injury switches on a communication cascade that reprograms heart cells and leads to heart regeneration in zebrafish.

Blood flow command center discovered in the brain
An international team of researchers has discovered a group of cells in the brain that may function as a 'master-controller' for the cardiovascular system, orchestrating the control of blood flow to different parts of the body.

Read More: Blood Flow News and Blood Flow Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.