Radiation from CT scans associated with increased risk for cancer

November 19, 2019

A new study in JNCI Cancer Spectrum finds that exposure to radiation from CT scans is associated with higher risks of developing thyroid cancer and leukemia.

Researchers here conducted study from a National Health Insurance dataset in Taiwan between 2000 and 2013. The study followed 22,853 thyroid cancer, 13,040 leukemia, and 20,157 non-Hodgkin lymphoma cases. Researchers consulted data from the National Health Insurance program to study demographic and medical information on disease diagnoses, procedures, and drug prescriptions, and the enrollment profiles of all patients. Patients were excluded if they were under 25 years at the time of the cancer diagnosis, had less than three years of follow-up before cancer diagnosis, or had a history of a cancer before the year 2000.

Results showed that patients who developed thyroid cancer and leukemia had significantly higher likelihood of having received CT scans. In studies that combined patients across age groups, exposure to medical CT scans was not associated with increased risk for non-Hodgkin lymphoma. However in patients between 36 and 45 years of age, there was a three-fold increased risk of non-Hodgkin lymphoma associated with CT scans. In older patients the association between exposure to CT scans and non-Hodgkin lymphoma was not evident.

Researchers concluded that patients receiving CT scans had in general marked increases in the risk of developing thyroid cancer and leukemia, especially in female patients and patients younger than 45.

"Our study found that CT scans are associated with an increased risk of thyroid cancer and leukemia in adults in all ages and with non-Hodgkin lymphoma in young adults," said Yu-Hsuan Joni Shao, one of the paper's authors. "The risk is stronger in patients who have higher cumulative doses from multiple scans. The increased numbers of people undergoing CT scans have become a public health issue."
-end-
The paper, "Exposure to Tomographic Scans and Cancer Risks," is available to the public on November 19, at one minute after midnight EST.

Direct questions about the study to:

Yu-Hsuan Joni Shao
Graduate Institute of Biomedical Informatics
Taipei Medical University
26 172-1 Section 2, Keelung Rd.,
Taipei, TAIWAN
jonishao@tmu.edu.tw

To request a copy of the study, please contact:

Emily Tobin
Emily.tobin@oup.com

Sharing on social media? Find Oxford Journals online at @OxfordJournals

Please acknowledge the Journal of the National Cancer Institute as a source in any articles.

Oxford University Press USA

Related Cancer Articles from Brightsurf:

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications.

UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies
A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.

Breast cancer treatment costs highest among young women with metastic cancer
In a fight for their lives, young women, age 18-44, spend double the amount of older women to survive metastatic breast cancer, according to a large statewide study by the University of North Carolina at Chapel Hill.

Cancer mortality continues steady decline, driven by progress against lung cancer
The cancer death rate declined by 29% from 1991 to 2017, including a 2.2% drop from 2016 to 2017, the largest single-year drop in cancer mortality ever reported.

Stress in cervical cancer patients associated with higher risk of cancer-specific mortality
Psychological stress was associated with a higher risk of cancer-specific mortality in women diagnosed with cervical cancer.

Cancer-sniffing dogs 97% accurate in identifying lung cancer, according to study in JAOA
The next step will be to further fractionate the samples based on chemical and physical properties, presenting them back to the dogs until the specific biomarkers for each cancer are identified.

Moffitt Cancer Center researchers identify one way T cell function may fail in cancer
Moffitt Cancer Center researchers have discovered a mechanism by which one type of immune cell, CD8+ T cells, can become dysfunctional, impeding its ability to seek and kill cancer cells.

More cancer survivors, fewer cancer specialists point to challenge in meeting care needs
An aging population, a growing number of cancer survivors, and a projected shortage of cancer care providers will result in a challenge in delivering the care for cancer survivors in the United States if systemic changes are not made.

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment.

American Cancer Society outlines blueprint for cancer control in the 21st century
The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that forms the basis of a national cancer control plan.

Read More: Cancer News and Cancer Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.