Lifestyle risks for cardiovascular disease differ between men and women

November 21, 2002

Epidemiologic studies have suggested that elevated plasma homocysteine (tHcy) concentrations are a risk factor for cardiovascular disease (CVD), and that several lifestyle factors influence tHcy levels. Publishing in the American Journal of Clinical Nutrition, Mennen et al. examined the effects of lifestyle on tHcy concentrations in a group of middle-aged French men and women and developed different recommendations for each gender, based on disparate findings regarding the influences of lifestyle on tHcy.

The subjects, 1139 women and 931 men, averaging 47 and 51 years old respectively, were participants in a long-term study of the effect of a daily antioxidant supplement on the incidence of cancer and CVD. Middle and Southern Europeans have different lifestyle habits than people in Anglo-Saxon countries, and the occurrence of CVD is lower in Southern Europe. All of the men and women randomly completed 24-hour dietary recall records, for a total of 6 records per year per subject. In concurrence with other studies of this kind, the researchers found that men had higher tHcy levels than women overall. Coffee and alcohol consumption appeared to have a significant effect on tHcy concentrations in women. Women who were at the highest level of coffee consumption had 15% higher tHcy concentrations than women at the lowest level, and the tHcy levels of women who consumed higher amounts of alcohol were 13% higher than those of light drinkers. For men, caloric intake, physical activity levels, dietary fiber and folate intake had significant influences on tHcy. Men with the lowest concentration of serum folate, which is a nutrient known to mediate tHcy levels, had 21% higher tHcy concentrations than those with high serum folate.

The authors suggest that modifiable lifestyle factors may produce significant CVD risk factor reduction. Both sexes can improve their plasma tHcy concentrations and reduce CVD risk by taking a daily antioxidant vitamin and mineral supplement.
Mennen, Louise I et al. Homocysteine, cardiovascular disease risk factors, and habitual diet in the French Supplementation with Antioxidant Vitamins and Minerals Study. Am J Clin Nutr 2002; 76:1279-89.

This media release is provided by The American Society for Clinical Nutrition to provide current information on nutrition-related research. This information should not be construed as medical advice. If you have a medical concern, consult your doctor. To see the complete text of this article, please go to:

For more information, please contact:

American Journal of Clinical Nutrition

Related Cardiovascular Disease Articles from Brightsurf:

Changes by income level in cardiovascular disease in US
Researchers examined changes in how common cardiovascular disease was in the highest-income earners compared with the rest of the population in the United States between 1999 and 2016.

Fighting cardiovascular disease with acne drug
Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg and Stanford University have found the cause of dilated cardiomyopathy - a leading cause of heart failure - and identified a potential treatment for it: a drug already used to treat acne.

A talk with your GP may prevent cardiovascular disease
Having a general practitioner (GP) who is trained in motivational interviewing may reduce your risk of getting cardiovascular disease.

Dilemma of COVID-19, aging and cardiovascular disease
Whether individuals should continue to take angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in the context of coronavirus disease 2019 (COVID-19) is discussed in this article.

Air pollution linked to dementia and cardiovascular disease
People continuously exposed to air pollution are at increased risk of dementia, especially if they also suffer from cardiovascular diseases, according to a study at Karolinska Institutet in Sweden published in the journal JAMA Neurology.

New insights into the effect of aging on cardiovascular disease
Aging adults are more likely to have - and die from - cardiovascular disease than their younger counterparts.

Premature death from cardiovascular disease
National data were used to examine changes from 2000 to 2015 in premature death (ages 25 to 64) from cardiovascular disease in the United States.

Ultrasound: The potential power for cardiovascular disease therapy
In the current issue of Cardiovascular Innovations and Applications volume 4, issue 2, pp.

Despite the ACA, millions of Americans with cardiovascular disease still can't get care
Cardiovascular disease (CVD) is the leading cause of death for Americans, yet millions with CVD or cardiovascular risk factors (CVRF) still can't access the care they need, even years after the implementation of the Affordable Care Act (ACA).

Excess weight and body fat cause cardiovascular disease
In the first Mendelian randomization study to look at this, researchers have found evidence that excess weight and body fat cause a range of heart and blood vessel diseases (rather than just being associated with it).

Read More: Cardiovascular Disease News and Cardiovascular Disease Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to