Medicine by media

November 21, 2005

Diane-35 (cyproterone-estradiol), an androgen-blocking combination drug with contraceptive properties, was approved for use as a second-line treatment for severe acne in women. Because of concerns about liver toxicity and an increased risk of venous thromboembolism, warnings were sent to physicians in December 2002 advising them not prescribe Diane-35 for birth control or mild acne.

In this brief report, Barbara Mintzes and Steve Morgan show that prescription rates for Diane-35 in British Columbia remained essentially unchanged after the warning.

In January 2003, however, the CBC aired a television documentary that featured interviews with users and physicians who believed that Diane-35 was an ordinary birth-control pill. Immediately afterward, usage rates dropped dramatically. The investigators also found that of the 33 095 women who received at least one prescription for Diane-35, over 45% (15 064) had no recorded evidence of having had acne.

Widely broadcast news stories may, one surmises, be more influential than Health Canada (or this medical journal).
Charts showing changes in prescription patterns for Diane-35 in British Columbia are available.

p. 1313 Medicine by media: Did a critical television documentary affect the prescribing of cyptroteroneestradiol (Diane-35) -- B. Mintzes et al

Canadian Medical Association Journal

Related Venous Thromboembolism Articles from Brightsurf:

Venous origin of brain blood-vessel malformations
In the condition known as cavernoma, lesions arise in a cluster of blood vessels in the brain, spinal cord or retina.

What is cerebral venous thrombosis? study finds blood clot condition on the rise
Cerebral venous thrombosis (CVT) occurs when a blood clot forms in one of the veins in the brain, preventing blood from draining out of the brain.

Need to check patient's jugular venous pressure? There's an app for that
A new report from cardiologists at UT Southwestern raises the hope that doctors will be able to visually check the jugular venous pressure of heart failure patients remotely, using the camera on a smartphone.

High rate of blood clots in COVID-19
COVID-19 is associated with a high incidence of venous thromboembolism, blood clots in the venous circulation, according to a study conducted by researchers at Brighton and Sussex Medical School (BSMS), UK.

Patients at a reduced risk of venous thromboembolism and persistent pain after partial versus total knee replacement
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2019) demonstrate reduced risk of venous thromboembolism and persistent pain, but increased risk of revision in partial versus total knee replacement in patients with osteoarthritis.

PET/CT imaging agent shows promise for better diagnosis of acute venous thromboembolism
Researchers report that a new nuclear medicine tracer may allow better diagnosis of acute venous thromboembolism (VTE).

ASH releases new clinical practice guidelines for venous thromboembolism
Venous thromboembolism (VTE), a term referring to blood clots in the veins, is a highly prevalent and far-reaching public health problem that can cause disability and death.

Comparable risk of recurrent venous thromboembolism between patients with unprovoked venous thromboembolism and patients with cancer
Patients with venous thromboembolism (VTE) carry a high risk of recurrence.

Perioperative short haul air travel associated with increased risk of venous thromboembolism
New research presented at the 2018 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) found a correlation between flying following hip or knee arthroplasty and an increased risk of venous thromboembolism (VTE).

New anti-clotting drugs not associated with higher risk of major bleeding
A new group of drugs used to treat patients with serious blood clots are not associated with a higher risk of major bleeding compared with the older anti-clotting drug, warfarin, finds a study published by The BMJ today.

Read More: Venous Thromboembolism News and Venous Thromboembolism Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to