Native Americans have decreased access to kidney transplants

November 24, 2015

Highlights San Diego, CA (November 24, 2015) -- Native Americans have decreased access to kidney transplants and are more likely to die on the waiting list than whites according to new research presented at ASN Kidney Week 2015 held November 3-8 in San Diego, CA. Researchers also found that while short-term outcomes after receiving a kidney transplant were similar, Native Americans had worse long-term survival outcomes compared to whites.

Native Americans are at increased risk for developing kidney disease, with the most-recent data estimating 15% of Native Americans have chronic kidney disease (CKD) stages 1-4. This population also has high rates of end-stage renal disease and lower rates of kidney transplantation. To examine these disparities, University of New Mexico researchers led by Sarah Stith, PhD, an applied microeconomist specializing in health care, reviewed data from the Organ Procurement and Transplantation Network (OPTN) over a 16-year period.

After analyzing wait-list removal reasons, post-transplant survival rates, and controlling for multiple factors (such as patient, donor, match characteristics), they found Native Americans were less likely to receive a kidney transplant (odds ratio [OR] 0.71 [95% CI 0.64-0.80]) and more likely to die while waiting for one (OR 1.88 [95% 0.89-3.94) than white individuals.

Although Native Americans demonstrated worse post-transplant survival at 2 years (OR 0.80 [95% CI 0.70-0.92]) and 3 years (OR 0.81 [95% CI 0.71-0.94]) compared to whites, this difference was not statistically significant.

"The decomposition of our results indicates that the disparity in 3-year post-transplant survival between Native Americans and whites is driven primarily by the prevalence of lower quality donors among Native Americans and a greater negative impact from such donor characteristics on survival among Native Americans," the authors concluded. "Native Americans also tend to receive transplants at centers associated with worse outcomes and would benefit disproportionately from receiving transplants at better centers."
-end-
Study: "The Difficult Road for Native Americans in Kidney Transplantation: Decreased Access and Reduced Long-Term Survival" (Abstract SA-PO1010).

Disclosure information is available at http://www.asn-online.org/education/kidneyweek/2015/program-faculty.aspx.

ASN Kidney Week 2015, the largest nephrology meeting of its kind, provided a forum for more than 13,000 professionals to discuss the latest findings in kidney health research and engage in educational sessions related to advances in the care of patients with kidney and related disorders. Kidney Week 2015 was held November 3-8, 2015, in San Diego, CA.

The content of this article does not reflect the views or opinions of The American Society of Nephrology (ASN). Responsibility for the information and views expressed therein lies entirely with the author(s). ASN does not offer medical advice. All content in ASN publications is for informational purposes only, and is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This content should not be used during a medical emergency or for the diagnosis or treatment of any medical condition. Please consult your doctor or other qualified health care provider if you have any questions about a medical condition, or before taking any drug, changing your diet or commencing or discontinuing any course of treatment. Do not ignore or delay obtaining professional medical advice because of information accessed through ASN. Call 911 or your doctor for all medical emergencies.

Founded in 1966, and with nearly 16,000 members, the American Society of Nephrology (ASN) leads the fight against kidney disease by educating health professionals, sharing new knowledge, advancing research, and advocating the highest quality care for patients.

CONTACTS: Kurtis Pivert, kpivert@asn-online.org, 202-699-0238

Bob Henkel, bhenkel@asn-online.org, 202-557-8360

American Society of Nephrology

Related Kidney Transplant Articles from Brightsurf:

The effects of social determinants of health on kidney transplant candidates
Social determinants of health are associated with patient-reported outcomes in adults who are eligible to undergo kidney transplantation evaluations.

Tailored education system to benefit kidney transplant patients
Researchers find their computer-tailored education system, 'Your Path to Transplant' increases knowledge and readiness to pursue kidney transplant.

Kidney transplant, the cost of accounting for patients' preferences
Taking into account patients' preferences can help speed up the organ allocation process and improve the life quality of the recipients, as shown by a joint study conducted by Ca' Foscari University and the University of Padua

New hope for kidney revival for transplant
Cell therapy delivered directly to the kidney can revive a 'marginal' organ, improving function and could offer new hope for providing more kidneys for transplant.

Are kidney transplant patients at higher risk? The European experience
The risk of death is relatively high in kidney transplant patients admitted to hospital with COVID-19.

The economic burden of kidney transplant failure in the United States
A recent analysis published in the American Journal of Transplantation estimates that for the average US patient who has undergone kidney transplantation, failure of the transplanted organ (graft failure) will impose additional medical costs of $78,079 and a loss of 1.66 quality-adjusted life years.

Mixed chimerism improves long-term kidney transplant outlook
Mixed chimerism - the continued mixing of donor and recipient blood cells following a transplant of blood progenitor cells - could improve outcomes for kidney transplant recipients, according to a new clinical study in about 50 patients.

Kidney paired donation is an excellent option for transplant candidates
An analysis compared transplant recipients who received kidneys through national kidney paired donation and those who received kidneys from other living donors (such as relatives, friends or other paired exchange mechanisms).

Mediterranean diet may help preserve the kidney health of transplant recipients
In a study of kidney transplant recipients, those with higher adherence to the Mediterranean diet were less likely to experience kidney function loss.

New blood test can detect rejection by antibodies after kidney transplant
A group of European scientists led by KU Leuven has found a biomarker that can identify patients with symptoms of kidney rejection symptoms after a transplant as a result of antibodies.

Read More: Kidney Transplant News and Kidney Transplant Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.