Nav: Home

No risk of heart attack associated with short-term use of traditional painkillers

November 27, 2005

Short-term use of painkiller drugs in the same family as ibuprofen does not increase the risk of having a heart attack. The results of a large study, published today in the open access journal BMC Medicine, confirm that taking traditional non-steroidal anti-inflammatory drugs (NSAIDs) in the recommended dose for less than a year does not increase the risk of having a heart attack. When taken regularly for more than one year, however, some traditional NSAIDs can slightly increase the risk of non-fatal heart attack. This does not apply to ibuprofen or naproxen, two of the most widely-used NSAIDs.

Luis A. García Rodríguez and Antonio González-Pérez from the Centro Español de Investigación Farmacoepidemiológica in Madrid, Spain, studied NSAID use in 4,975 patients who had had a heart attack and 20,000 healthy control individuals. Their results show that taking NSAIDs for less than a year does not increase the risk of heart attack. Regular NSAID use for longer than one year, however, can increase the risk of non-fatal heart attack by 20%. The authors analysed the heart attack risk associated with three of the most commonly used NSAIDs. Their results show that individual NSAIDs have different cardiovascular effects. Taking ibuprofen for over a year does not increase the risk of heart attack, while long-term diclofenac use causes a small increase in the risk of having a heart attack. Long-term use of naproxen could have a small protective effect according to this study.
-end-
Article:
Long-term use of traditional non-steroidal anti-inflammatory drugs and the risk of myocardial infarction in the general population Luis A Garcia Rodriguez and Antonio Gonzalez-Perez
BMC Medicine 2005, 3:17 (28 November 2005)

BioMed Central

Related Heart Attack Articles:

Heart cells respond to heart attack and increase the chance of survival
The heart of humans and mice does not completely recover after a heart attack.
A simple method to improve heart-attack repair using stem cell-derived heart muscle cells
The heart cannot regenerate muscle after a heart attack, and this can lead to lethal heart failure.
Mount Sinai discovers placental stem cells that can regenerate heart after heart attack
Study identifies new stem cell type that can significantly improve cardiac function.
Fixing a broken heart: Exploring new ways to heal damage after a heart attack
The days immediately following a heart attack are critical for survivors' longevity and long-term healing of tissue.
Heart patch could limit muscle damage in heart attack aftermath
Guided by computer simulations, an international team of researchers has developed an adhesive patch that can provide support for damaged heart tissue, potentially reducing the stretching of heart muscle that's common after a heart attack.
How the heart sends an SOS signal to bone marrow cells after a heart attack
Exosomes are key to the SOS signal that the heart muscle sends out after a heart attack.
Heart attack patients taken directly to heart centers have better long-term survival
Heart attack patients taken directly to heart centers for lifesaving treatment have better long-term survival than those transferred from another hospital, reports a large observational study presented today at Acute Cardiovascular Care 2019, a European Society of Cardiology congress.
Among heart attack survivors, drug reduces chances of second heart attack or stroke
In a clinical trial involving 18,924 patients from 57 countries who had suffered a recent heart attack or threatened heart attack, researchers at the University of Colorado Anschutz Medical Campus and fellow scientists around the world have found that the cholesterol-lowering drug alirocumab reduced the chance of having additional heart problems or stroke.
Oxygen therapy for patients suffering from a heart attack does not prevent heart failure
Oxygen therapy does not prevent the development of heart failure.
I have had a heart attack. Do I need open heart surgery or a stent?
New advice on the choice between open heart surgery and inserting a stent via a catheter after a heart attack is launched today.
More Heart Attack News and Heart Attack Current Events

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Rethinking Anger
Anger is universal and complex: it can be quiet, festering, justified, vengeful, and destructive. This hour, TED speakers explore the many sides of anger, why we need it, and who's allowed to feel it. Guests include psychologists Ryan Martin and Russell Kolts, writer Soraya Chemaly, former talk radio host Lisa Fritsch, and business professor Dan Moshavi.
Now Playing: Science for the People

#538 Nobels and Astrophysics
This week we start with this year's physics Nobel Prize awarded to Jim Peebles, Michel Mayor, and Didier Queloz and finish with a discussion of the Nobel Prizes as a way to award and highlight important science. Are they still relevant? When science breakthroughs are built on the backs of hundreds -- and sometimes thousands -- of people's hard work, how do you pick just three to highlight? Join host Rachelle Saunders and astrophysicist, author, and science communicator Ethan Siegel for their chat about astrophysics and Nobel Prizes.