New technique for measuring blood flow to brain in babies

November 28, 2002

Authors of a research letter in this week's issue of THE LANCET describe how an ultrasound technique can be used as a non-invasive way of measuring blood flow to the brain in babies, which may be of benefit to infants with brain disorders arising from restrictions in cerebral blood flow.

Changes in the rate of blood flow to the brain in premature and full-term babies may be the cause of ischaemic brain damage; up until now, however, it has not been possible to quantitatively measure blood flow to the brain without exposing babies to radiation.

Martin Schöning and colleagues from University Childrens Hospital, Tübingen, Germany, used ultrasound techniques to measure the cerebral blood flow of 67 healthy premature and full-term babies. Cerebral blood flow was much greater in full-term babies (around 85 millilitres per minute) compared with premature babies (around 33 millilitres per minute). The investigators comment how this non-invasive method will allow quantitative bedside monitoring of brain blood flow in babies at risk of brain damage, and could also be used to monitor the effects of preventive therapies for neurological disorders in infants.

Martin Schöning comments: "The innocuous ultrasound method presented here enables us for the first time to investigate the physiological development of brain blood flow in preterm and term infants as, for ethical reasons, the established radionuclide techniques cannot be given to healthy babies. There are many potential applications of this method in clinics and research--especially in premature babies in which the risk of developing ischaemic or haemorrhagic brain lesions is higher than at any time up to old age."
-end-
Contact: Dr Martin Schöning,
University Children's Hospital, D-72076 Tübingen, Germany;
T) (49-707-1298-3771);
F) (49-707-129-5473);
E) martin.schoening@med.uni-tuebingen.de

Lancet

Related Blood Flow Articles from Brightsurf:

Brain regions with impaired blood flow have higher tau levels
In Alzheimer's disease, impaired blood flow to brain regions coincides with tau protein buildup.

3D ultrasound enables accurate, noninvasive measurements of blood flow
A 3D ultrasound system provides an effective, noninvasive way to estimate blood flow that retains its accuracy across different equipment, operators and facilities, according to a new study.

Blood flow recovers faster than brain in micro strokes
Work by a Rice neurobiologist shows that increased blood flow to the brain is not an accurate indicator of neuronal recovery after a microscopic stroke.

Exercise improves memory, boosts blood flow to brain
Scientists have collected plenty of evidence linking exercise to brain health, with some research suggesting fitness may even improve memory.

3D VR blood flow to improve cardiovascular care
Biomedical engineers are developing a massive fluid dynamics simulator that can model blood flow through the full human arterial system at subcellular resolution.

MRI shows blood flow differs in men and women
Healthy men and women have different blood flow characteristics in their hearts, according to a new study.

Brain blood flow sensor discovery could aid treatments for high blood pressure & dementia
A study led by researchers at UCL has discovered the mechanism that allows the brain to monitor its own blood supply, a finding in rats which may help to find new treatments for human conditions including hypertension (high blood pressure) and dementia.

Blood flow monitor could save lives
A tiny fibre-optic sensor has the potential to save lives in open heart surgery, and even during surgery on pre-term babies.

Changes in blood flow tell heart cells to regenerate
Altered blood flow resulting from heart injury switches on a communication cascade that reprograms heart cells and leads to heart regeneration in zebrafish.

Blood flow command center discovered in the brain
An international team of researchers has discovered a group of cells in the brain that may function as a 'master-controller' for the cardiovascular system, orchestrating the control of blood flow to different parts of the body.

Read More: Blood Flow News and Blood Flow Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.