Nav: Home

What are effects of smoked, vaporized marijuana in infrequent adult users?

November 30, 2018

BottomLine: Researchers compared the effects of smoked versus vaporized cannabis at two different doses and a placebo dose in a small study of 17 healthy adults who weren't regular cannabis users. Participants felt the effects of smoked and vaporized cannabis at a 10-mg dose of the psychoactive component THC, including modest cognitive impairment, while a 25-mg dose of THC produced more pronounced drug effects and substantial impairment of cognitive and psychomotor functioning. Vaporized cannabis produced stronger drug effects on users and higher blood concentrations of THC compared with equal doses of smoked cannabis. The study was limited by a small range of doses.
-end-
Authors: Ryan Vandrey, Ph.D., Johns Hopkins University School of Medicine, Baltimore, and coauthors

Related Material: The invited commentary, "Peering Through the Haze of Smoked vs Vaporized Cannabis--To Vape or Not to Vape?" by Nadia Solowij, Ph.D., University of Wollongong, Australia, also is available on the For The Media website.

To Learn More: The full study is available on the For The Media website.

(doi:10.1001/jamanetworkopen.2018.4841)

Editor's Note: The article contains conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Want to embed a link to this study in your story?: Links will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2018.4841

About JAMA Network Open:JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

JAMA Network Open

Related Cognitive Articles:

More amyloid in the brain, more cognitive decline
A new study from the Center for Vital Longevity at The University of Texas at Dallas has found that the amount of amyloid plaques in a person's brain predicts the rate at which his or her cognition will decline in the next four years.
Cognitive skills differ across cultures and generations
An innovative study of children and parents in both Hong Kong and the United Kingdom reveals cultural differences in important cognitive skills among adolescents but not their parents.
Mild cognitive impairment (MCI)
Greek researchers demonstrated the potential of a self-administered virtual supermarket cognitive training game for remotely detecting mild cognitive impairment (MCI), without the need for an examiner, among a sample of older adults.
Benefits of cognitive training in dementia patients unclear
Positive effects of cognitive training in healthy elderly people have been reported, but data regarding its effects in patients with dementia is unclear.
Emotions are cognitive, not innate, researchers conclude
Emotions are not innately programmed into our brains, but, in fact, are cognitive states resulting from the gathering of information, New York University Professor Joseph LeDoux and Richard Brown, a professor at the City University of New York, conclude.
An impulsive cognitive style comes with implications, researchers say
A new study finds a wide range of subtle but measurable tendencies in the thinking of people who would rather snatch a quick reward than wait for a bigger one.
Link between sleep and cognitive impairment in the elderly
Daytime sleepiness is very common in the elderly with prevalence rates of up to 50 percent.
Does metabolic syndrome affect cognitive abilities?
A new study of US adolescents shows an association between metabolic syndrome and impairments in reading, attention, and working memory.
Exercise and healthy diets associated with better cognitive functioning
Findings published this week in the Journal of Public Health reveal that both younger and older Canadian adults who engage in regular physical activity, consume more fruits and vegetables and are normal weight or overweight have overall better cognitive functioning.
Cognitive ability varies, but prejudice is universal
A new study shows both high and low cognitive ability have distinct prejudices against particular groups.

Related Cognitive Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Changing The World
What does it take to change the world for the better? This hour, TED speakers explore ideas on activism—what motivates it, why it matters, and how each of us can make a difference. Guests include civil rights activist Ruby Sales, labor leader and civil rights activist Dolores Huerta, author Jeremy Heimans, "craftivist" Sarah Corbett, and designer and futurist Angela Oguntala.
Now Playing: Science for the People

#521 The Curious Life of Krill
Krill may be one of the most abundant forms of life on our planet... but it turns out we don't know that much about them. For a create that underpins a massive ocean ecosystem and lives in our oceans in massive numbers, they're surprisingly difficult to study. We sit down and shine some light on these underappreciated crustaceans with Stephen Nicol, Adjunct Professor at the University of Tasmania, Scientific Advisor to the Association of Responsible Krill Harvesting Companies, and author of the book "The Curious Life of Krill: A Conservation Story from the Bottom of the World".