More than 41 million Americans need colorectal cancer screening

December 01, 2004

Bethesda, Maryland (Dec. 1, 2004) - More than 41 million Americans who are candidates for colorectal cancer screening have not been screened for this second-leading cancer killer, the first time the unscreened population has been quantified. According to a study published today in the American Gastroenterological Association (AGA) journal Gastroenterology, sufficient capacity exists to screen the unscreened population within one year using fecal occult blood testing (FOBT) followed by diagnostic colonoscopy for positive tests.

Guidelines of multiple agencies and professional societies underscore the importance of colorectal cancer screening for all individuals 50 years of age and older. Approved tests include barium enema, FOBT, flexible sigmoidoscopy and colonoscopy. Each screening option has advantages and disadvantages.

"Given the enormous number of people who are eligible for screening but have not been screened, it is clear that regardless of the test, colorectal cancer screening is underutilized," notes Bernard Levin, MD, AGA spokesperson. "Men and women who are otherwise fit should be screened for colorectal polyps and cancer because colorectal cancer can be prevented by polypectomy and cured when detected early."

Researchers at the Centers for Disease Control and Prevention (CDC) used data from the U.S. Bureau of the Census and CDC's National Health Interview Survey to estimate the size of the population that has not received colorectal cancer screening. In addition, a companion paper published in this issue of Gastroenterology reports findings of the CDC's national Survey of Endoscopic Capacity which estimates the number of flexible sigmoidoscopies and colonoscopies performed in a year, and the maximum number that physicians could perform given an increased demand.

Although ample capacity exists for screening with FOBT, a test that is inexpensive and widely available, findings of this study suggest that capacity limitations exist for flexible sigmoidoscopy and colonoscopy. Limitations may be due, in large part, to the fact that only certain specialists are trained to perform colonoscopies and both tests tend to be more expensive than FOBT. Depending on the proportion of available capacity used for colorectal cancer screening in the United States, it could take up to 10 years to screen the unscreened population using colonoscopy alone, not taking into account the need for repeat screening tests or keeping the currently screened population up-to-date on screening.

"This is the first time that the size of the unscreened population has been measured, then compared to the number of tests being performed, to determine whether the public health community can meet the demand for widespread colorectal cancer screening," said Laura C. Seeff, MD, lead study author with the CDC. "We hope these results will help shape colorectal cancer screening programs that may emerge in ensuing years."

Routine screening tests can detect the large, more dangerous polyps, which can be removed during a colonoscopy. Guidelines published by the U.S. Multisociety Task Force on Colorectal Cancer in February 2003, recommend patients who have small polyps removed have follow-up or "surveillance" colonoscopies every five years. However, many patients are receiving surveillance colonoscopies more frequently, therefore reducing overall screening capacity.

"Shifting colonoscopy resources away from excessive, unnecessary surveillance examinations could increase the available supply of screening colonoscopy," notes Theodore R. Levin, MD, in an editorial accompanying the CDC study. Dr. Levin is the Regional Director of Colorectal Cancer Screening and a gastroenterologist at Kaiser Permanente, Northern California.

Since the study results are based on national data, results may not bear out in smaller geographic areas. Assessments are underway in 15 states to take into account differences in availability of screening methods and to further guide local planning for colorectal cancer screening.

"These capacity estimates provide a foundation from which planning for widespread colorectal cancer screening and follow-up at the national and regional levels can occur," said Seeff.
-end-
More information about colorectal cancer screening and prevention is available at www.gastro.org.

About the Studies
Researchers at the CDC conducted a study to determine current capacity of colorectal cancer screening in the United States. The study used data from the U.S. Bureau of the Census and CDC's National Health Interview Survey to estimate the number of people not being currently screened for colorectal cancer nationally and regionally, as well as the number of screening tests needed to screen this population. In a complementary study, researchers surveyed approximately 1,800 medical practices to determine the number of lower endoscopic procedures performed and the potential number that could be performed if demand for the screenings was increased. The survey results showed approximately three million flexible sigmoidoscopies and 14 million colonoscopies were performed in 2002. Physicians reported an ability to increase the number of flexible sigmoidoscopies by nearly 30 percent and the number of colonoscopies by 60 percent annually.

About the AGA
The American Gastroenterological Association (AGA) is dedicated to the mission of advancing the science and practice of gastroenterology. Founded in 1897, the AGA is the oldest medical-specialty society in the United States. The AGA's 14,000 members include physicians and scientists who research, diagnose and treat disorders of the gastrointestinal tract and liver. On a monthly basis, the AGA publishes two highly respected journals, Gastroenterology and Clinical Gastroenterology and Hepatology. The AGA's annual meeting is Digestive Disease Week, which is held each May and is the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

About Gastroenterology
Gastroenterology, the official journal of the AGA, is the most prominent journal in the subspecialty and is in the top one percent of indexed medical journals internationally. The journal publishes clinical and basic studies of all aspects of the digestive system, including the liver and pancreas, as well as nutrition. The journal is abstracted and indexed in Biological Abstracts, CABS, Chemical Abstracts, Current Contents, Excerpta Medica, Index Medicus, Nutrition Abstracts and Science Citation Index.

American Gastroenterological Association

Related Cancer Articles from Brightsurf:

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications.

UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies
A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.

Breast cancer treatment costs highest among young women with metastic cancer
In a fight for their lives, young women, age 18-44, spend double the amount of older women to survive metastatic breast cancer, according to a large statewide study by the University of North Carolina at Chapel Hill.

Cancer mortality continues steady decline, driven by progress against lung cancer
The cancer death rate declined by 29% from 1991 to 2017, including a 2.2% drop from 2016 to 2017, the largest single-year drop in cancer mortality ever reported.

Stress in cervical cancer patients associated with higher risk of cancer-specific mortality
Psychological stress was associated with a higher risk of cancer-specific mortality in women diagnosed with cervical cancer.

Cancer-sniffing dogs 97% accurate in identifying lung cancer, according to study in JAOA
The next step will be to further fractionate the samples based on chemical and physical properties, presenting them back to the dogs until the specific biomarkers for each cancer are identified.

Moffitt Cancer Center researchers identify one way T cell function may fail in cancer
Moffitt Cancer Center researchers have discovered a mechanism by which one type of immune cell, CD8+ T cells, can become dysfunctional, impeding its ability to seek and kill cancer cells.

More cancer survivors, fewer cancer specialists point to challenge in meeting care needs
An aging population, a growing number of cancer survivors, and a projected shortage of cancer care providers will result in a challenge in delivering the care for cancer survivors in the United States if systemic changes are not made.

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment.

American Cancer Society outlines blueprint for cancer control in the 21st century
The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that forms the basis of a national cancer control plan.

Read More: Cancer News and Cancer Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.