Eating margarine with Stanol lowers cholesterol by 10 percent

December 01, 1999

ROCHESTER, MINN. -- A new study reports that eating three servings a day of a margarine-like spread containing a plant substance called stanol can reduce cholesterol levels by as much as 10 percent. It also found no ill effects from using it.

More than 300 people with mildly elevated cholesterol levels participated in the multi-center study. Three groups ate margarines fortified with three different quantities of stanols, a plant product that inhibits absorption of cholesterol by the body. One group ate regular margarine. After eight weeks, all those who ate the fortified margarine lowered their total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C -- so called "bad cholesterol"). Those who ate the regular margarine had a slight increase in cholesterol levels.

The greatest reduction in the study -- 6 percent TC and 10 percent LDL-C -- was in the group which ate the spread containing one gram of stanol. This is the same quantity found in the product now on the market in the United States.

Tu Nguyen, M.D., a Mayo Clinic endocrinologist and principal investigator of the study, said "the results confirm that consumption of plant stanol-fortified foods is a useful tool for lowering serum cholesterol in the population."
-end-


Mayo Clinic

Related Cholesterol Articles from Brightsurf:

Cholesterol's effects on cellular membranes
The findings have far-reaching implications in the general understanding of disease, the design of drug delivery methods, and many other biological applications that require specific assumptions about the role of cholesterol in cell membranes.

Autism-cholesterol link
Study identifies genetic link between cholesterol alterations and autism.

Microbes might manage your cholesterol
Researchers discover a link between human blood cholesterol levels and a gene in the microbiome that could one day help people manage their cholesterol through diet, probiotics, or entirely new types of treatment.

Experimental cholesterol-lowering drug effective at lowering bad cholesterol, study shows
Twice-yearly injections of an experimental cholesterol-lowering drug, inclisiran, were effective at reducing low-density lipoprotein (LDL) cholesterol, often called bad cholesterol, in patients already taking the maximum dose of statin drugs, according to data of the ORION-10 trial presented Saturday, Nov.

Rethinking how cholesterol is integrated into cells
Cholesterol is best known in connection with cardiovascular disease, but cholesterol is also vital for many fundamental processes in the body.

Seed oils are best for LDL cholesterol
Using a statistical technique called network meta-analysis, researchers have combined the results of dozens of studies of dietary oils to identify those with the best effect on patients' LDL cholesterol and other blood lipids.

Cholesterol leash: Key tethering protein found to transport cellular cholesterol
Cholesterol is an essential component of living organisms, but the mechanisms that transport cholesterol inside the cell are poorly understood.

New way to treat cholesterol may be on the horizon
A breakthrough discovery by scientists at Houston Methodist Research Institute could change the way we treat cholesterol.

How low should LDL cholesterol go?
New analysis shows that in a high-risk population, achieving ultra-low LDL cholesterol levels, down to <10 mg/dL, safely results in additional lowering of risk of cardiovascular events.

Does boosting 'good' cholesterol really improve your health?
A new review addresses the mysteries behind 'good' HDL cholesterol and why boosting its levels does not necessarily provide protection from cardiovascular risk for patients.

Read More: Cholesterol News and Cholesterol Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.