Imaging Camera Developed At Toshiba Stroke Research Center Could Provide Views Of Tiniest Brain Vessels

December 02, 1998

CHICAGO -- Researchers at the University at Buffalo's Toshiba Stroke Research Center have developed a prototype camera that can turn blurred X-ray images of brain stents made of thin wire into images clear enough to detect the condition of wire as fine as a hair.

The development marks the first use of this technology, called a high-resolution region-of-interest microangiographic digital detector, for viewing devices, called stents, placed inside blood vessels in the brain. The stents can prevent stroke by shoring up weak spots in arteries or blocking off aneurysms.

The UB prototype provides images that are significantly clearer than can be produced by any current system, and may allow the viewing of even the tiniest blood vessels in the circulation system, Stephen Rudin, Ph.D., UB professor of radiology and physics, reported here today (Dec. 2, 1998). The prototype and its image-enhancing capabilities were introduced by him at the annual meeting of the Radiological Society of North America.

Rudin heads a research group composed primarily of physicists within the Toshiba Stroke Research Center, an interdisciplinary research effort involving UB neurosurgeons, engineers, physicists, biophysicists and radiologists.

Scientists at the Toshiba Stroke Research Center are in the forefront of research into intravascular treatments for stroke and other circulation-related disorders of the brain. Intravascular interventions use the body's circulation system as a tunnel to the brain. Neurosurgeons or neuroradiologists thread micro-thin instruments through the large artery in the groin until they reach the damaged area. This approach avoids the need to open the skull.

Having clear X-ray images of the vessels and instruments is critical to reaching the repair site without damaging vessels along the way.

"Even with the most advanced imaging equipment available at present, we weren't seeing features we knew existed," Rudin said. "We expect this detector prototype to help us locate the stent optimally in the vessel, visualize its integrity in place and reposition it if necessary. If you can't see exactly what condition the stent is in when it's deployed, it's not possible to change the deployment.

"The detector technology is similar to that being introduced now in mammography," he said. "In mammography, the site being viewed is static. We are developing the technology so it can be used in rapid-sequence imaging at that very high resolution."

Rudin said this enhanced imaging capability should allow viewing of vessels as small as the 50-200-micron ones at the very end of the circulation system of the brain, called perforators, which cannot be seen at all with conventional imaging equipment.

"Without this new capability, we would have difficulty treating aneurysms that were near these vessels because we cannot see well enough to avoid damaging the very small healthy perforators."

The research was funded by the U.S. Army and the Toshiba Stroke Research Center. Additional members of the research team are Ajay Wakhloo, M.D., and Daniel Bednarek, Ph.D., both associate professors in the UB School of Medicine and Biomedical Sciences, and Chang-Ying J. Yang and William E. Granger, doctoral candidates.
-end-


University at Buffalo

Related Stroke Articles from Brightsurf:

Stroke alarm clock may streamline and accelerate time-sensitive acute stroke care
An interactive, digital alarm clock may speed emergency stroke care, starting at hospital arrival and through each step of the time-sensitive treatment process.

Stroke patients with COVID-19 have increased inflammation, stroke severity and death
Stroke patients who also have COVID-19 showed increased systemic inflammation, a more serious stroke severity and a much higher rate of death, compared to stroke patients who did not have COVID-19, according a retrospective, observational, cross-sectional study of 60 ischemic stroke patients admitted to UAB Hospital between late March and early May 2020.

'Time is vision' after a stroke
University of Rochester researchers studied stroke patients who experienced vision loss and found that the patients retained some visual abilities immediately after the stroke but these abilities diminished gradually and eventually disappeared permanently after approximately six months.

More stroke awareness, better eating habits may help reduce stroke risk for young adult African-Americans
Young African-Americans are experiencing higher rates of stroke because of health conditions such as high blood pressure, diabetes and obesity, yet their perception of their stroke risk is low.

How to help patients recover after a stroke
The existing approach to brain stimulation for rehabilitation after a stroke does not take into account the diversity of lesions and the individual characteristics of patients' brains.

Kids with headache after stroke might be at risk for another stroke
A new study has found a high incidence of headaches in pediatric stroke survivors and identified a possible association between post-stroke headache and stroke recurrence.

High stroke impact in low- and middle-income countries examined at 11th World Stroke Congress
Less wealthy countries struggle to meet greater need with far fewer resources.

Marijuana use might lead to higher risk of stroke, World Stroke Congress to be told
A five-year study of hospital statistics from the United States shows that the incidence of stroke has risen steadily among marijuana users even though the overall rate of stroke remained constant over the same period.

We need to talk about sexuality after stroke
Stroke survivors and their partners are not adequately supported to deal with changes to their relationships, self-identity, gender roles and intimacy following stroke, according to new research from the University of Sydney.

Standardized stroke protocol can ensure ELVO stroke patients are treated within 60 minutes
A new study shows that developing a standardized stroke protocol of having neurointerventional teams meet suspected emergent large vessel occlusion (ELVO) stroke patients upon their arrival at the hospital achieves a median door-to-recanalization time of less than 60 minutes.

Read More: Stroke News and Stroke Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.