Study finds young women in UK face unnecessary surgery for suspected appendicitis

December 04, 2019

Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. A new BJS study examined whether existing risk prediction models can reliably identify which UK patients with a low risk of appendicitis presenting to hospitals with acute right abdominal pain have appendicitis.

This largest worldwide multicentre study of suspected appendicitis in recent years included two-thirds of British hospitals providing emergency surgery (154 UK acute surgical units), making the findings generalisable across the UK. In addition, comparative data were collected from 120 hospitals across Italy, Portugal, the Republic of Ireland, and Spain. The study showed that women had a disproportionately higher risk of hospital admission without surgical intervention. Women who did undergo surgery had high rates of surgeries that removed a normal appendix.

Most risk prediction models were found to be unable to safely identify significant numbers of patients at low risk of appendicitis.

"Appendicectomy is the UK's most common emergency operation. Our study shows the world's highest published rate of normal appendicectomy--that is, surgery for suspected appendicitis but the diagnosis is wrong, and a normal appendix is removed," said corresponding author Aneel Bhangu, MBChB, PhD, FRCS, of the University of Birmingham. "The group most affected are young women and, every year, thousands of women aged 16 to 45 are suffering a sub-optimal experience in the UK."
-end-


Wiley

Related Appendicitis Articles from Brightsurf:

CODA appendicitis trial shows risks and benefits of treating appendicitis with antibiotics
Antibiotics may be a good choice for some, but not all, patients with appendicitis, according to results from the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) Trial reported today in the New England Journal of Medicine.

Benefits, risks seen with antibiotics-first for appendicitis
Antibiotics are a good choice for some patients with appendicitis but not all, according to study results published today in the New England Journal of Medicine.

Study shows antibiotics may be viable treatment option for appendicitis
In the largest randomized US study of appendicitis published today in the New England Journal of Medicine, researchers from Henry Ford Health System and 24 other sites around the US report that seven in 10 patients who received antibiotics avoided surgery and that patients who took antibiotics for symptom relief fared no worse in the short term than those who underwent surgery.

Research shows benefits/risks of treating appendicitis with antibiotics instead of surgery
NEJM: Results of a first-of-its-kind clinical trial shed light on when antibiotics instead of surgery might be the better choice for treating appendicitis in some patients, according to researchers with UTHealth, who led the Houston trial sites.

Pregnant women have better outcomes after immediate surgery for complicated appendicitis
Pregnant women who underwent immediate surgery to treat a ruptured or abscessed appendix and their fetuses had significantly better outcomes than those whose condition was managed without an operation.

Children with cognitive delays are more likely to have CT scan to diagnose appendicitis
Computed tomography (CT) is used at a higher rate than ultrasound in children with developmental and cognitive impairments to diagnose appendicitis, even though CT scans increase radiation risk in smaller bodies.

Antibiotics alone successfully treat uncomplicated appendicitis in children
Of 1,068 patients from 10 health centers enrolled in the study, 67.1% of those who elected to initially manage their care through antibiotics alone experienced no harmful side effects and did not later require an appendectomy by their one-year follow-up appointment.

Why is appendicitis not always diagnosed in the emergency department?
A new study examines the factors associated with a potentially missed diagnosis of appendicitis in children and adults in the emergency department.

How does long-term quality of life, patient satisfaction compare for appendicitis treatments?
Researchers compared long-term quality of life and patient satisfaction among those patients who were treated with antibiotics or who had their appendix removed for uncomplicated acute appendicitis.

Complications of measles can include hepatitis, appendicitis, and viral meningitis, doctors warn
The complications of measles can be many and varied, and more serious than people might realise, doctors have warned in the journal BMJ Case Reports after treating a series of adults with the infection.

Read More: Appendicitis News and Appendicitis Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.