UMass Medical School enrolling participants in National Children's Study pilot program

December 05, 2012

WORCESTER, MA -- UMass Medical School is enrolling expectant mothers from Worcester County in a pilot program in preparation for the much larger National Children's Study, the landmark undertaking in which 100,000 children will be followed from the womb to age 21 to determine the environment's impact on growth, development and onset of disease.

"We are excited to announce that we are enrolling our first participants in this pilot study, an effort that may significantly benefit children's health for generations to come," said Marianne Felice, MD, professor of pediatrics and obstetrics at UMMS and principal investigator of the NCS Worcester County Study site Center. "The National Children's Study is the largest nation-wide longitudinal study of a birth cohort of children ever undertaken in the United States. The data collected will form the policies by which we treat children in the future."

UMMS was awarded a $3.6 million, one-year contract from the National Institute of Child Health and Human Development to recruit study participants from local OB/GYN offices and hospitals. This method of recruitment, called provider-based sampling, is an alternative to the original National Children's Study plan in which data collectors would knock on doors in targeted neighborhoods across the country.

Dr. Felice said the goal is to determine if provider-based sampling is a more efficient and cost-effective way of recruiting for the main study.

Family Health Center of Worcester is the first practice identified by the NIH for participation in the Worcester pilot study. UMMS is working with Family Health staff to arrange appointments for data collectors to meet patients at their first pre-natal appointments and ask them to consider participating in the study. Women who agree to take part will meet at home with data collectors twice over the course of their pregnancies and again after their babies are born. At each visit, the women will answer a series of questions about their health and the environment in which they live. Participants must be residents of Worcester County and sign up at their first pre-natal appointment with their medical care provider.

"This is an exciting new venture in the 40-year partnership between Family Health Center of Worcester, Inc. and UMass Medical School," said Frances Anthes, CEO and president of Family Health. "Family Health is thrilled to open the door to our community's participation in the work of the medical school as the first site in this important research project. This groundbreaking project will teach us all how to create healthier lives for our children."

Eight data collectors have been hired and certified for the program, along with two dozen additional new hires to support the effort. A total of 15 physician's offices and pre-natal clinics will be chosen to participate. The sites are being chosen by the national office of the NCS to ensure that there is a representative sample of Worcester County.

This is the second National Children's Study contract for UMMS. In 2007, UMMS was awarded a $16.2 million, five-year contract and served as one of 40 sites across the country conducting formative research projects to determine the least costly and most efficient way to conduct the National Children's Study. Research has ranged from the best ways to collect environmental samples such as water, dust, soil, and air, to how to engage the fathers of the infants in the study. After all the formative studies are completed, the central office of the National Children's Study will have more information on the best practices for conducting the main study.

Data from the National Children's Study will be used to help determine how to prevent and treat some of the nation's most pressing health problems, including autism, birth defects, diabetes, and obesity.
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About the University of Massachusetts Medical School

The University of Massachusetts Medical School has built a reputation as a world-class research institution, consistently producing noteworthy advances in clinical and basic research. The Medical School attracts more than $250 million in research funding annually, 80 percent of which comes from federal funding sources. The work of UMMS researcher Craig Mello, PhD, an investigator of the prestigious Howard Hughes Medical Institute (HHMI), and his colleague Andrew Fire, PhD, then of the Carnegie Institution of Washington, toward the discovery of RNA interference was awarded the 2006 Nobel Prize in Physiology or Medicine and has spawned a new and promising field of research, the global impact of which may prove astounding. UMMS is the academic partner of UMass Memorial Health Care, the largest health care provider in Central Massachusetts. For more information, visit www.umassmed.edu.

University of Massachusetts Medical School

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