Annals of Internal Medicine, tip sheet for December 7, 1999

December 06, 1999

EMBARGOED FOR RELEASE UNTIL 5 P.M., EST, MONDAY, DEC. 6, 1999 American College of Physicians-American Society of Internal Medicine Annals of Internal Medicine Tip Sheet, December 7, 1999 Annals of Internal Medicine is published by the American College of Physicians-American Society of Internal Medicine (ACP-ASIM), an organization of more than 115,000 physicians trained in internal medicine. The following highlights are not intended to substitute for articles as sources of information. For an article, call 1-800-523-1546, ext. 2656 or 215-351-2656. * * * Sensitive Test Found Micrometastases; May Help Stage Colorectal Cancer RT-PCR, a new molecular biology test, detected a substance in the lymph nodes which may be a biomarker of future recurrence of colorectal cancer (Article, p. 805). A retrospective study looked at tissues of 21 patients with Stage II colorectal cancer that was presumably cured. The substance, guanylyl cyclase C, was found in the lymph nodes of the 10 whose cancer subsequently recurred and not in the 11 who remained disease-free after six years. * * * ACP-ASIM Cautions Physicians About Selling Products From Their Offices ACP-ASIM says that physicians must maintain high ethical standards if they chose to sell products from their offices (Position Paper, p. 863). The products must be essential to the patient's care; clinically relevant to the patients' conditions; proven effective in treating the condition; not easily available to the patient because of geographic or time constraints; and urgently needed. [Call for a separate news release.] * * * Fibromyalgia: Update on Diagnosis and Treatment but Still No Cure Fibromyalgia, an elusive illness characterized by muscle pain, stiffness, poor sleep and tender points on the body, affects about 3.7 million people (Update, p. 850). An update reviews the literature on diagnosis and treatment of the illness and finds that drug therapies have only limited success managing the illness. The author recommends a multidisciplinary approach including both drug and non-drug strategies. * * * Article on Buying Drugs on the Internet. FDA Editorial: Buyer Beware This article (p. 830) and editorial (p. 861) were posted on the ACP-ASIM Web site on Sept. 27 in advance of publication because of their important public health messages. # # #

American College of Physicians

Related Colorectal Cancer Articles from Brightsurf:

Colorectal cancer treatment: the winning combinations
Chemotherapy has distressing side effects for patients and increases the risk of developing resistance to the treatment.

A new model to predict survival in colorectal cancer
This signature could be useful in clinical practice, especially for colorectal cancer diagnosis and therapy.

Roadmap to reducing colorectal cancer deaths
The American Gastroenterological Association has outlined a strategy to increase the number of people screened via tests that are more convenient, accurate and less expensive and tailored to people's individual cancer risks.

Study provides new insight on colorectal cancer growth
A new study by researchers at the University of Kentucky identifies a novel function of the enzyme spermine synthase to facilitate colorectal cancer growth.

Researchers ID target for colorectal cancer immunotherapy
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified a target for colorectal cancer immunotherapy.

Colorectal cancer partner-in-crime identified
A protein that helps colorectal cancer cells spread to other parts of the body could be an effective treatment target.

Cancer cell reversion may offer a new approach to colorectal cancer treatment
A novel approach to reverse the progression of healthy cells to malignant ones may offer a more effective way to eradicate colorectal cancer cells with far fewer side effects, according to a KAIST research team based in South Korea.

A novel pathway to target colorectal cancer
Survival rates for patients with late-stage colorectal cancer are dismal, and new therapeutic strategies are needed to improve outcomes.

Colorectal cancer rates in Canada
The incidence of colorectal cancer among younger adults increased in recent years in this analysis of data from Canadian national cancer registries that included about 688,000 new colorectal cancers diagnosed over more than 40 years.

Cancer drugs promote stem cell properties of colorectal cancer
Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Mannheim University Medical Center have now discovered that a certain group of cancer drugs (MEK Inhibitors) activates the cancer-promoting Wnt signalling pathway in colorectal cancer cells.

Read More: Colorectal Cancer News and Colorectal Cancer Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to