New guidelines for treating the complications of brain tumours

December 09, 2020

The brain can be affected by a number of different types of tumour and this leads to serious complications such as epileptic attacks, brain edema, haemorrhage, or thrombosis. Hitherto, there have been no uniform standards available for the diagnosis and treatment of these common symptoms. An international team of researchers comprising experts from the leading oncology societies ESMO (European Society for Medical Oncology) and EANO (European Association of Neuro-Oncology) has now compiled international guidelines and standards for the treatment of these complications, and these have been published in the top journal Annals of Oncology (Impact Factor: 18.2). As EANO President, Matthias Preusser, Head of the Division of Oncology (MedUni Vienna's Department of Medicine I) initiated these international guidelines and has played a leading role in coordinating them in his capacity as last author.

"Every year, around 18 million people worldwide are diagnosed with cancer and up to every second patient with an advanced tumour develops brain metastases, especially in cases of lung, breast or skin cancer. Due to the breadth of this field, the new guidelines are of huge significance," explains Preusser. "Two of the largest societies have therefore joined forces to produce uniform standards."

With the aid of algorithms and numerous diagrams, a reference work has been produced to ensure that patients throughout the world receive high-quality treatment for the complications associated with brain tumours. Questions such as "how does one manage brain edema?" or "what should I do in the event of an epileptic attack or neurocognitive impairment?" are addressed in detail by the interdisciplinary panel of authors.

"The new guidelines that we have compiled can be applied and implemented all over the world and should therefore lead to a significant increase in patient safety," stresses Preusser, who has simultaneously co-authored guidelines for the correct treatment of glioma (a specific type of central nervous system brain tumour), which have recently been published in the leading journal Nature Reviews Clinical Oncology (Impact Factor: 53.2,
Cancer facts

Every year, cancer is responsible for around 25% of all deaths in Austria. Around 40,000 new cases are diagnosed each year. The commonest cancers in women are breast cancer (29%), lung and bowel cancer (10% each). For men it is prostate cancer (23%), followed by lung cancer (14%) and then bowel cancer (12%). There has been a significant increase in relative 5-year survival over the last few decades and it now stands at around 60%.

Medical University of Vienna

Related Cancer Articles from Brightsurf:

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications.

UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies
A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.

Breast cancer treatment costs highest among young women with metastic cancer
In a fight for their lives, young women, age 18-44, spend double the amount of older women to survive metastatic breast cancer, according to a large statewide study by the University of North Carolina at Chapel Hill.

Cancer mortality continues steady decline, driven by progress against lung cancer
The cancer death rate declined by 29% from 1991 to 2017, including a 2.2% drop from 2016 to 2017, the largest single-year drop in cancer mortality ever reported.

Stress in cervical cancer patients associated with higher risk of cancer-specific mortality
Psychological stress was associated with a higher risk of cancer-specific mortality in women diagnosed with cervical cancer.

Cancer-sniffing dogs 97% accurate in identifying lung cancer, according to study in JAOA
The next step will be to further fractionate the samples based on chemical and physical properties, presenting them back to the dogs until the specific biomarkers for each cancer are identified.

Moffitt Cancer Center researchers identify one way T cell function may fail in cancer
Moffitt Cancer Center researchers have discovered a mechanism by which one type of immune cell, CD8+ T cells, can become dysfunctional, impeding its ability to seek and kill cancer cells.

More cancer survivors, fewer cancer specialists point to challenge in meeting care needs
An aging population, a growing number of cancer survivors, and a projected shortage of cancer care providers will result in a challenge in delivering the care for cancer survivors in the United States if systemic changes are not made.

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment.

American Cancer Society outlines blueprint for cancer control in the 21st century
The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that forms the basis of a national cancer control plan.

Read More: Cancer News and Cancer Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to