Science and legal experts debate future uses and impact of human genome editing in Gender & the Genome

December 13, 2016

New Rochelle, NY, December 13, 2016--Precise, economical genome editing tools such as CRISPR have made it possible to make targeted changes in genes, which could be applied to human embryos to correct mutations, prevent disease, or alter traits. A panel of experts discusses the controversies related to the possibility of editing the human embryonic genome and creating man-made modifications that would be passed on to future generations, in a Roundtable Discussion published in Gender and the Genome, a new peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

Journal Editor-in-Chief Marianne Legato, MD, PhD (hon. c.), FACP, Columbia University (New York, NY) moderated a lively and insightful discussion among distinguished panelists George Church, PhD, Harvard University and Massachusetts Institute of Technology (Cambridge, MA), Henry Greely, JD, Stanford University School of Law (CA), Tetsuya Ishii, PhD, Hokkaido University (Japan), Virginia Miller, PhD, Mayo Clinic (Rochester, MN), and Justin Killian, Esq and Sherif Moussa, Esq, both from Foundation for Gender-Specific Medicine (New York, NY).

The Roundtable Discussion is entitled "Editing the Human Genome: Progress and Controversies."

Among the scientific, societal, and legal implications of a future in which we may be able to modify the genetic makeup of human embryos, the Roundtable panelists discussed what a "balanced regulatory approach" to oversee the use of genome editing tools might look like, potential safety issues, the concept of using genome editing to make cosmetic choices for a prospective child, and the legal implications of parents' rights to manipulate the genome of an embryo.

"Our ability to manipulate the human genome is a paradigm shift that trumps Darwinian evolution," says Dr. Legato.
About the Journal

Gender and the Genome, published quarterly in print and online, will feature evidence-based original research, reviews, perspectives, and commentaries that will illuminate the impact of biological sex on 21st century technology and its effect on human life. The international editorial board will include the most forward-thinking leaders in gender-specific medicine to engage the community of molecular biologists, engineers, ethicists, anthropologists, and legal experts engaged in a dialogue about the nature and implications of 21st century technology.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including DNA and Cell Biology, Human Gene Therapy, Nucleic Acid Therapeutics, and Cellular Reprogramming. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

About the Foundation for Gender-Specific Medicine

The Foundation for Gender Specific-Medicine supports the investigation of the ways in which biological sex and gender affect normal human function and the experience of disease. One of the discipline's pioneers, Marianne J. Legato, MD, PhD (hon. c.), FACP, established the Foundation as a continuation of her work with The Partnership for Gender-Specific Medicine at Columbia University.

Mary Ann Liebert, Inc./Genetic Engineering News

Related Genome Articles from Brightsurf:

Genome evolution goes digital
Dr. Alan Herbert from InsideOutBio describes ground-breaking research in a paper published online by Royal Society Open Science.

Breakthrough in genome visualization
Kadir Dede and Dr. Enno Ohlebusch at Ulm University in Germany have devised a method for constructing pan-genome subgraphs at different granularities without having to wait hours and days on end for the software to process the entire genome.

Sturgeon genome sequenced
Sturgeons lived on earth already 300 million years ago and yet their external appearance seems to have undergone very little change.

A sea monster's genome
The giant squid is an elusive giant, but its secrets are about to be revealed.

Deciphering the walnut genome
New research could provide a major boost to the state's growing $1.6 billion walnut industry by making it easier to breed walnut trees better equipped to combat the soil-borne pathogens that now plague many of California's 4,800 growers.

Illuminating the genome
Development of a new molecular visualisation method, RNA-guided endonuclease -- in situ labelling (RGEN-ISL) for the CRISPR/Cas9-mediated labelling of genomic sequences in nuclei and chromosomes.

A genome under influence
References form the basis of our comprehension of the world: they enable us to measure the height of our children or the efficiency of a drug.

How a virus destabilizes the genome
New insights into how Kaposi's sarcoma-associated herpesvirus (KSHV) induces genome instability and promotes cell proliferation could lead to the development of novel antiviral therapies for KSHV-associated cancers, according to a study published Sept.

Better genome editing
Reich Group researchers develop a more efficient and precise method of in-cell genome editing.

Unlocking the genome
A team led by Prof. Stein Aerts (VIB-KU Leuven) uncovers how access to relevant DNA regions is orchestrated in epithelial cells.

Read More: Genome News and Genome Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to