Nav: Home

Efforts needed to stop the spread of carbapenem-resistant Acinetobacter baumannii

December 14, 2016

Acinetobacter baumannii is the cause of difficult-to-treat infections in healthcare settings in Europe due to its increasing resistance to antimicrobial agents, in particular the carbapenems. Outbreaks of carbapenem-resistant A. baumannii in healthcare facilities have been reported in Europe and worldwide.

Infections with carbapenem-resistant A. baumannii occur in patients with severe underlying diseases, mainly in intensive care units, and are often related to invasive procedures or indwelling devices. However, such infections are increasingly being reported in patients admitted to conventional medical and surgical wards. A. baumannii is difficult to eradicate once it has become endemic.

Recent ECDC data from the European survey on carbapenemase-producing Enterobacteriaceae (EuSCAPE) project and from the European Antimicrobial Resistance Surveillance Network (EARS-Net) confirmed that although there is already a high resistance baseline in some countries, there has been an overall increase of carbapenem-resistant A. baumannii in Europe.

These data confirm an already alarming situation that continues to worsen in many EU/EEA countries. While carbapenems traditionally were the antibiotics of choice for treatment of A. baumannii infections, resistance to these drugs has led to increased use of colistin as last-line treatment. Although still rare, resistance to colistin in A. baumannii is also increasingly being reported in Europe.

ECDC's risk assessment highlights the need of increased efforts to face this significant threat to patients and healthcare systems in all EU/EEA countries and outlines options to reduce risks through clinical management, prevention of transmission in hospitals and other healthcare settings, prevention of cross-border transmission, and improvement of preparedness of EU/EEA countries.
-end-
Rapid risk assessment: carbapenem-resistant Acinetobacter baumannii in healthcare settings

Summary of the latest data on antibiotic resistance in the European Union, EARS-Net surveillance data

ECDC Surveillance Atlas of Infectious Diseases

Carbapenemase-producing Enterobacteriaceae in Europe: assessment by national experts from 38 countries, May 2015

European Antimicrobial Resistance Surveillance Network (EARS-Net)

European Surveillance of Antimicrobial Consumption Network (ESAC-Net)

ECDC Antimicrobial Resistance and Healthcare-associated Infections Programme

European Centre for Disease Prevention and Control (ECDC)

Related Infections Articles:

Young infants with fever may be more likely to develop infections
Infants with a high fever may be at increased risk for infections, according to research from Penn State College of Medicine.
Hospital infections declining in Canada
There is good news on the infection front: infections acquired by patients in Canadian hospitals are declining, with a 30% reduction between 2009 and 2017, according to new research in CMAJ (Canadian Medical Association Journal).
Helminthic infections may be beneficial against HIV-1
Infection with parasitic helminths can reduce the susceptibility of T-cells to HIV-1 infection, according to a study published Sept.
Clostridium difficile infections may have a friend in fungi
The pathogen Clostridium difficile, which causes one of the most common hospital-acquired infections in the United States, may have accomplices that until now have gone largely unnoticed.
Waking up sleeping bacteria to fight infections
Researchers in the group of Jan Michiels (VIB-KU Leuven Center for Microbiology) identified a mechanism of how sleepy bacteria wake up.
Typhoid vaccine may protect against other infections
New research by the University of Liverpool and Liverpool School of Tropical Medicine shows that vaccination with weakened strains of Salmonella may also protect against other infections.
New AI can detect urinary tract infections
New AI developed at the University of Surrey could identify and help reduce one of the top causes of hospitalisation for people living with dementia: urinary tract infections (UTI).
Even the best healthcare facilities can do more to prevent infections
Healthcare-associated infections can be reduced by up to 55 percent by systematically implementing evidence-based infection prevention and control strategies, according to a review of 144 studies published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America (SHEA).
Francisella tularensis infections from foods unlikely
Francisella (F.) tularensis is a highly virulent bacterial pathogen that is resistant to environmental stresses and causes tularemia.
Deeper insight into viral infections
W├╝rzburg researchers have developed a new analysis technique that sheds more light on viral infections.
More Infections News and Infections Current Events

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Rethinking Anger
Anger is universal and complex: it can be quiet, festering, justified, vengeful, and destructive. This hour, TED speakers explore the many sides of anger, why we need it, and who's allowed to feel it. Guests include psychologists Ryan Martin and Russell Kolts, writer Soraya Chemaly, former talk radio host Lisa Fritsch, and business professor Dan Moshavi.
Now Playing: Science for the People

#538 Nobels and Astrophysics
This week we start with this year's physics Nobel Prize awarded to Jim Peebles, Michel Mayor, and Didier Queloz and finish with a discussion of the Nobel Prizes as a way to award and highlight important science. Are they still relevant? When science breakthroughs are built on the backs of hundreds -- and sometimes thousands -- of people's hard work, how do you pick just three to highlight? Join host Rachelle Saunders and astrophysicist, author, and science communicator Ethan Siegel for their chat about astrophysics and Nobel Prizes.