Nav: Home

Wrap up: Key recommendations from AGA's 2015 guidelines

December 16, 2015

Bethesda, MD (Dec. 16, 2015) -- Clinical practice guidelines are critical to reducing physician variation and providing high-quality patient care.

In 2015, the American Gastroenterological Association (AGA) issued six clinical practice guidelines, all published in AGA's official journal Gastroenterology, offering current, evidence-based point-of-care recommendations to guide physicians at the bedside.

Review the following compilation of new AGA guidelines release in 2015. To view all of AGA's clinical practice guidelines, as well as accompanying clinical decision support tools and patient guideline summaries, visit

1. Medical Management of Microscopic Colitis

November 2015

(This guideline is currently an Article in Press and is subject to minor edits. Available to media by request.)

In patients with symptomatic microscopic colitis, AGA recommends first-line treatment with budesonide for induction and, when appropriate, maintenance therapy.

2. Management of Acute Diverticulitis

October 2015

This guideline suggests that antibiotics be used selectively, rather than routinely, in patients with acute diverticulitis. It also recommends a fiber-rich diet or fiber supplementation, and identifies future areas of research.

3. Role of Upper GI Biopsy to Evaluate Dyspepsia in the Adult Patient in the Absence of Visible Mucosal Lesions

August 2015

AGA recommends against obtaining endoscopic biopsy of a normal-appearing esophagus in an immunocompromised patient with dyspepsia, providing evidence that this alone would have no added value.

4. Diagnosis and Management of Lynch Syndrome

July 2015

All colorectal cancer patients should undergo tumor testing to see if they carry Lynch syndrome, according to this AGA guideline. AGA also recommends performing a surveillance colonoscopy every one-to-two years in patients with Lynch syndrome, versus less frequent intervals.

5. Diagnosis and Management of Asymptomatic Neoplastic Pancreatic Cysts

April 2015

This guideline changes clinical practice by recommending a two-year screening interval for asymptomatic pancreatic cysts of any size and stopping surveillance after five years if there is no change. This guideline also limits surgery to those who will receive the most benefit.

6. Prevention and Treatment of Hepatitis B Virus Reactivation During Immunosuppressive Drug Therapy

January 2015

Preventing HBV reactivation in patients on long-term immunosuppressive therapy involves screening those at risk, identifying patients for risk based on HBV serologic status and the type of immunosuppression, and consideration of prophylaxis with anti-hepatitis B therapeutics; all three steps are detailed in this guideline.

AGA develops clinical practice guidelines using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology and best practices as outlined by the Institute of Medicine. Our guidelines are regularly reviewed for accuracy. For more information, visit
About the AGA Institute

The American Gastroenterological Association is the trusted voice of the GI community. Founded in 1897, the AGA has grown to include more than 16,000 members from around the globe who are involved in all aspects of the science, practice and advancement of gastroenterology. The AGA Institute administers the practice, research and educational programs of the organization.

About Gastroenterology

Gastroenterology, the official journal of the AGA Institute, is the most prominent scientific journal in the specialty and is in the top 1 percent of indexed medical journals internationally. The journal publishes clinical and basic science studies of all aspects of the digestive system, including the liver and pancreas, as well as nutrition. The journal is abstracted and indexed in Biological Abstracts, Current Awareness in Biological Sciences, Chemical Abstracts, Current Contents, Excerpta Medica, Index Medicus, Nutrition Abstracts and Science Citation Index. For more information, visit

Like AGA and Gastroenterology on Facebook.

Join AGA on LinkedIn

Follow us on Twitter @AmerGastroAssn

Check out our videos on YouTube

American Gastroenterological Association

Related Lynch Syndrome Articles:

Increasing the age limit for Lynch syndrome genetic testing may save lives
Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts for around 5 percent of all colon cancers.
Avocados may help combat the metabolic syndrome
A new review investigates the effects of avocados on different components of metabolic syndrome, which is a clustering of risk factors including high blood sugar, cholesterol, blood pressure, and body mass index.
What does congenital Zika syndrome look like?
In a new paper, researchers at University of California San Diego School of Medicine, along with colleagues in Brazil and Spain, describe the phenotypic spectrum or set of observable characteristics of congenital Zika (ZIKV) syndrome, based upon clinical evaluations and neuroimaging of 83 Brazilian children with presumed or confirmed ZIKV congenital infections.
A new immunologic and endocrine syndrome
The name of the gene is Armc5, for Armadillo repeat containing 5.
Double effort against Rett's syndrome
Although our genes normally come in pairs but sometimes one of them is missing (haploinsufficiency) leading sometimes to serious diseases.
New neurodevelopmental syndrome identified
Columbia University researchers discovered a new neurodevelopmental syndrome and the genetic mutation that causes it.
New drug target for Rett syndrome
Harvard Stem Cell Institute researchers have identified a faulty signaling pathway that, when corrected, in mice ameliorates the symptoms of Rett syndrome, a devastating neurological condition.
Insensitive irritable bowel syndrome
For the first time, biopsies of patients with irritable bowel syndrome have shown that the nerves in their gut wall respond poorly to a cocktail of inflammatory substances.
MECP2 duplication syndrome is reversible
Research led by Huda Zoghbi, M.D., at Baylor College of Medicine and HHMI and published today in the journal Nature reveals that the MECP2 Duplication Syndrome is reversible.
AGA recommends all patients with colorectal cancer get tested for Lynch syndrome
All colorectal cancer patients should undergo tumor testing to see if they carry Lynch syndrome, the most common inherited cause of colorectal cancer, according to a new guideline was published in Gastroenterology, the official journal of the American Gastroenterological Association.

Related Lynch Syndrome Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Climate Crisis
There's no greater threat to humanity than climate change. What can we do to stop the worst consequences? This hour, TED speakers explore how we can save our planet and whether we can do it in time. Guests include climate activist Greta Thunberg, chemical engineer Jennifer Wilcox, research scientist Sean Davis, food innovator Bruce Friedrich, and psychologist Per Espen Stoknes.
Now Playing: Science for the People

#527 Honey I CRISPR'd the Kids
This week we're coming to you from Awesome Con in Washington, D.C. There, host Bethany Brookshire led a panel of three amazing guests to talk about the promise and perils of CRISPR, and what happens now that CRISPR babies have (maybe?) been born. Featuring science writer Tina Saey, molecular biologist Anne Simon, and bioethicist Alan Regenberg. A Nobel Prize winner argues banning CRISPR babies won’t work Geneticists push for a 5-year global ban on gene-edited babies A CRISPR spin-off causes unintended typos in DNA News of the first gene-edited babies ignited a firestorm The researcher who created CRISPR twins defends...