Nav: Home

Plants use a molecular clock to predict when they'll be infected

December 16, 2015

  • Plants are unable to maintain a high level of resistance to infection 24/7
  • Fungal infection appears more likely to occur at dawn
  • Plants use their molecular clock to raise resistance levels before dawn in anticipation of infection
  • Molecular clock and immune system found to be connected by a single protein
Plants are able to predict when infections are more likely to occur and regulate their immune response accordingly, new research has found.

Led by the University of Warwick the researchers discovered that a plants' molecular clock is connected to their immune system to increase levels of resistance to infection at dawn - the time at which fungal infections appear most likely to occur, with plants unable to maintain the highest level of resistance at all times of day.

The researchers identified a single protein, JAZ6, in the plant cell which drives this time-of-day difference in the effectiveness of the immune response, with it connecting the plant clock to the immune system.

Arguing that they can now use JAZ6 to pick out the key parts of the plant immune response controlling resistance to fungal pathogens, the researchers say they can now focus on how to improve disease resistance in crops by molecular breeding.

Whilst previous research had shown that resistance against bacterial pathogens varied at different times of the day the new research has for the first time shown that the same is true for resistance against a fungal pathogen. The University of Warwick's new research is also the first to identify a mechanism of how the internal plant clock is driving the difference in plant immunity at dawn and night.

Molecular (circadian) clocks drive the daily rhythms in many organisms, from humans to insects to plants and even marine algae.

They are the internal time keepers that enable organisms to anticipate predictable changes during a 24 hour period.

Lead researcher Dr Katherine Denby, of the University of Warwick's School of Life Science, explains:

"Plants are able to predict when pathogen infection is more likely to occur and regulate their immune response to combat this, with plants being more resistant to infection after inoculation at dawn compared to inoculation at night. The difference in a plant's resistance to infection at different times of the day is driven by its circadian clock rather than daily light/dark changes, with the differences existing regardless of whether you put the plants in constant light for a day and then infect at what would be dawn or night."

The researchers conducted the research by infecting plants with Botrytis cinerea spores every three hours over a 24-hour day and measuring the subsequent lesions that developed.

The researchers then observed that the plants inoculated in the morning developed much smaller lesions and were more resistant to disease compared to those plants which were inoculated at night. Those inoculated at night had significantly larger lesions and far more growth of the pathogen in the leaves.

University of Warwick PhD student Claire Stoker explains:

"We infected plants with a dysfunctional circadian clock in the morning and at night with our fungal pathogen and observed that the plant no longer had a difference in resistance at the two times of day. This pattern showed us that resistance must be driven by the plant's internal clock."

The research, Jasmonate signalling drives time-of-day differences in susceptibility of Arabidopsis to the fungal pathogen Botrytis cinerea, is published by, The Plant Journal.
-end-
Notes for Editors:

  • The researchers found that the variation in the plant immune system was unconnected to the regulation of light.
Images:

University of Warwick

Related Immune System Articles:

Using the immune system as a defence against cancer
Research published today in the British Journal of Cancer has found that a naturally occurring molecule and a component of the immune system that can successfully target and kill cancer cells, can also encourage immunity against cancer resurgence.
First impressions go a long way in the immune system
An algorithm that predicts the immune response to a pathogen could lead to early diagnosis for such diseases as tuberculosis
Filming how our immune system kill bacteria
To kill bacteria in the blood, our immune system relies on nanomachines that can open deadly holes in their targets.
Putting the break on our immune system's response
Researchers have discovered how a tiny molecule known as miR-132 acts as a 'handbrake' on our immune system -- helping us fight infection.
Decoding the human immune system
For the first time ever, researchers are comprehensively sequencing the human immune system, which is billions of times larger than the human genome.
More Immune System News and Immune System Current Events

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Rethinking Anger
Anger is universal and complex: it can be quiet, festering, justified, vengeful, and destructive. This hour, TED speakers explore the many sides of anger, why we need it, and who's allowed to feel it. Guests include psychologists Ryan Martin and Russell Kolts, writer Soraya Chemaly, former talk radio host Lisa Fritsch, and business professor Dan Moshavi.
Now Playing: Science for the People

#537 Science Journalism, Hold the Hype
Everyone's seen a piece of science getting over-exaggerated in the media. Most people would be quick to blame journalists and big media for getting in wrong. In many cases, you'd be right. But there's other sources of hype in science journalism. and one of them can be found in the humble, and little-known press release. We're talking with Chris Chambers about doing science about science journalism, and where the hype creeps in. Related links: The association between exaggeration in health related science news and academic press releases: retrospective observational study Claims of causality in health news: a randomised trial This...