New edition of a classic molecular biology textbook from CSHL Press and Benjamin Cummings

December 19, 2007

A new edition of the most widely used undergraduate textbook in molecular biology, Molecular Biology of the Gene, has just been released. It incorporates the latest in research and technological advances while retaining the distinctive characteristics of earlier editions that have made this a superior textbook for generations of students. Written by six authors with outstanding teaching and research credentials, the book will also be useful to professional scientists looking for a concise, up-to-date summary of the field. It was jointly published by Cold Spring Harbor Laboratory Press and Benjamin Cummings, an imprint of Pearson Education.

The first edition, which appeared in 1965, was written by James D. Watson. More recent editions of the book have been co-authored by Watson and five highly respected biologists to provide current, comprehensive, and authoritative coverage of this fast-changing discipline. These additional authors are Tania A. Baker (MIT), Stephen P. Bell (MIT), Alexander Gann (CSHL), Michael Levine (UC Berkeley), and Richard Losick (Harvard).

Now in its sixth edition, Molecular Biology of the Gene has been thoroughly revised. Content updates have been made to every chapter, and medical insights that have emerged from our understanding of basic molecular biology have been included. Two all-new chapters discuss regulatory RNAs (Chapter 18) and genomics and systems biology (Chapter 20). These chapters focus on RNAi and microRNAs, the opportunities offered by the new generation of genome technologies, and the elucidation of gene regulatory networks.

The twenty-two chapters offer balanced coverage of prokaryotic and eukaryotic systems, and are divided into five major sections. The chapters in Part 1 provide a historical basis for the field and include descriptions of fundamental chemical concepts. Part 2 covers the structures of DNA, RNA, and chromatin, as well as the maintenance of genetic material through replication, recombination, and repair. A comprehensive survey of transcription, splicing, and translation is offered in Part 3, and the regulation of these processes is discussed in Part 4. Finally, Part 5 presents standard techniques and model organisms commonly used in molecular biology studies.

Also new to the book are a series of color-coded boxes that describe key experiments, techniques, medical connections, and advanced concepts. These boxes help to support the narrative and to clarify key concepts throughout the book.

"Web Animation" icons are also placed throughout the text, and these direct students to the expanded companion Web site (http://www.aw-bc.com/watson). This Web site contains interactive tutorials, animations, critical-thinking exercises, and a glossary, which are designed to reinforce fundamental concepts and to help visualize complex concepts.

Supplementary instructor resources, including a CD-ROM and transparency acetates, are also available. The dual-platform CD-ROM contains high-resolution files of all art and tables from the book in JPEG and PowerPoint formats, as well as answers to the critical-thinking questions posed to students on the companion Web site. The transparencies feature approximately 300 four-color illustrations from the text as selected by the authors.
-end-
About the book:Molecular Biology of the Gene, 6th edition, (ISBN 9780805395921) is 841 pp. in length (illus., index) and is available in hardcover. The book's accompanying Web site is at http://www.aw-bc.com/watson. For more information, visit http://www.cshlpress.com/link/mbog6.htm and http://www.aw-bc.com/catalog/academic/product/0,1144,080539592X,00.html.

Requests for examination copies for textbook adoptions should be sent to Benjamin Cummings at www.pearsonhighered.com. The Instructor Resource CD-ROM (ISBN: 9780321527660) and Transparency Acetates (ISBN: 9780321536396) are freely available to adopters.

About the authors:

James D. Watson was the sole author of the first, second, and third editions of Molecular Biology of the Gene, and a co-author of the fourth and fifth editions. He is also a co-author of two other textbooks: Molecular Biology of the Cell and Recombinant DNA. Tania A. Baker is the Whitehead Professor of Biology at the Massachusetts Institute of Technology and an Investigator of the Howard Hughes Medical Institute. Stephen P. Bell is a Professor of Biology at the Massachusetts Institute of Technology and an Investigator of the Howard Hughes Medical Institute. Alexander Gann is Editorial Director of Cold Spring Harbor Laboratory Press and a faculty member of the Watson School of Biological Sciences at Cold Spring Harbor Laboratory. Michael Levine is a Professor of Molecular and Cell Biology at the University of California, Berkeley, and is also Co-Director of the Center for Integrative Genomics. Richard Losick is the Maria Moors Cabot Professor of Biology, a Harvard College Professor, and a Howard Hughes Medical Institute Professor in the Faculty of Arts and Sciences at Harvard University.

About Cold Spring Harbor Laboratory Press:

Cold Spring Harbor Laboratory Press is an internationally renowned publisher of books, journals, and electronic media, located on Long Island, New York. Since 1933, it has furthered the advance and spread of scientific knowledge in all areas of genetics and molecular biology, including cancer biology, plant science, bioinformatics, and neurobiology. It is a division of Cold Spring Harbor Laboratory, an innovator in life science research and the education of scientists, students, and the public. For more information, visit www.cshlpress.com.

About Benjamin Cummings:

Benjamin Cummings is an imprint of the world's largest educational publisher, Pearson Education.

Cold Spring Harbor Laboratory

Related Molecular Biology Articles from Brightsurf:

Likely molecular mechanisms of SARS-CoV-2 pathogenesis are revealed by network biology
Researchers have built an interactome that includes the lung-epithelial cell host interactome integrated with a SARS-CoV-2 interactome.

Cell biology: Your number's up!
mRNAs program the synthesis of proteins in cells, and their functional lifetimes are dynamically regulated.

Cell biology: All in a flash!
Scientists of Ludwig-Maximilians-Universitaet (LMU) in Munich have developed a tool to eliminate essential proteins from cells with a flash of light.

A biology boost
Assistance during the first years of a biology major leads to higher retention of first-generation students.

Scientists find biology's optimal 'molecular alphabet' may be preordained
Life uses 20 coded amino acids (CAAs) to construct proteins.

Molecular biology: Phaser neatly arranges nucleosomes
LMU researchers have, for the first time, systematically determined the positioning of the packing units of the fruit fly genome, and discovered a new protein that defines their relationship to the DNA sequence.

Molecular virologist fights influenza at the molecular level
In research to improve influenza therapies against H7N9 and other influenza strains, Chad Petit and his University of Alabama at Birmingham colleagues have detailed the binding site and mechanism of inhibition for two small-molecule experimental inhibitors of influenza viruses.

The complicated biology of garlic
Researchers generally agree that garlic, used for thousands of years to treat human disease, can reduce the risk of developing certain kinds of cancers, cardiovascular disease, and type 2 diabetes.

Study suggests molecular imaging strategy for determining molecular classifications of NSCLC
Recent findings suggest a novel positron emission tomography (PET) imaging approach determining epidermal growth factor receptor (EGFR) mutation status for improved lung cancer patient management.

The biology of color
Scientists are on a threshold of a new era of color science with regard to animals, according to a comprehensive review of the field by a multidisciplinary team of researchers led by professor Tim Caro at UC Davis.

Read More: Molecular Biology News and Molecular Biology Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.