Incidence of stroke decreases over last 50 years

December 26, 2006

The incidence of stroke in the U.S. over the past 50 years has declined, although the severity of stroke has not, according to a study in the December 27 issue of JAMA.

Stroke continues to be a major public health concern, with more than 750,000 new strokes occurring each year in the United States. It is the third leading cause of death behind heart disease and cancer and the leading neurologic cause of long-term disability, according to background information in the article. Prior estimates of long-term trends in the incidence and severity of stroke have varied. Determining trends could help guide health programs, public policy, and the allocation of research funding.

Raphael Carandang, M.D., of Boston University, and colleagues examined data from the Framingham Study (health study, with participants initially recruited in 1948) to determine long-term trends in the incidence, lifetime risk, severity, and 30-day risk of death from clinical stroke. This study included 9,152 Framingham Study original participants and offspring undergoing follow-up for up to 50 years over three consecutive time-periods (1950-1977, 1978-1989, and 1990-2004), with ascertainment of stroke risk factor data every 2 years and active surveillance for occurrence of stroke or death.

The researchers found that the age-adjusted annual incidence of clinical stroke and atherothrombotic brain infarctions (ABI) in participants age 55 to 94 years decreased over the 3 periods. The incidence of clinical stroke decreased significantly. Across the 3 periods, the lifetime risk of clinical stroke (by age 90 years) decreased from 19.5 percent to 14.5 percent in men age 65 years and from 18.0 percent to 16.1 percent in women. Age-adjusted stroke severity did not vary across periods; however, death within 30 days of stroke decreased significantly in men (from 23 percent to 14 percent) but not significantly in women (from 21 percent to 20 percent).

"The severity of stroke has not decreased and 30-day mortality has decreased significantly only in men, perhaps due to an older age at onset of stroke and more severe strokes in women. These sobering trends emphasize that while improved control of risk factors has lowered incidence of stroke, there is a need for greater primary prevention efforts to reduce the lifetime risk, severity, and 30-day mortality following stroke," the authors conclude.
-end-
(JAMA. 2006;296:2939-2946. Available pre-embargo to the media at www.jamamedia.org)

Editor's Note: This study was supported by grants from the National Institute of Neurological Disorders and Stroke and the National Heart, Lung, and Blood Institute's Framingham Heart Study. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

For More Information: Contact the JAMA/Archives Media Relations Department at 312-464-JAMA or email: mediarelations@jama-archives.org.

The JAMA Network Journals

Related Stroke Articles from Brightsurf:

Stroke alarm clock may streamline and accelerate time-sensitive acute stroke care
An interactive, digital alarm clock may speed emergency stroke care, starting at hospital arrival and through each step of the time-sensitive treatment process.

Stroke patients with COVID-19 have increased inflammation, stroke severity and death
Stroke patients who also have COVID-19 showed increased systemic inflammation, a more serious stroke severity and a much higher rate of death, compared to stroke patients who did not have COVID-19, according a retrospective, observational, cross-sectional study of 60 ischemic stroke patients admitted to UAB Hospital between late March and early May 2020.

'Time is vision' after a stroke
University of Rochester researchers studied stroke patients who experienced vision loss and found that the patients retained some visual abilities immediately after the stroke but these abilities diminished gradually and eventually disappeared permanently after approximately six months.

More stroke awareness, better eating habits may help reduce stroke risk for young adult African-Americans
Young African-Americans are experiencing higher rates of stroke because of health conditions such as high blood pressure, diabetes and obesity, yet their perception of their stroke risk is low.

How to help patients recover after a stroke
The existing approach to brain stimulation for rehabilitation after a stroke does not take into account the diversity of lesions and the individual characteristics of patients' brains.

Kids with headache after stroke might be at risk for another stroke
A new study has found a high incidence of headaches in pediatric stroke survivors and identified a possible association between post-stroke headache and stroke recurrence.

High stroke impact in low- and middle-income countries examined at 11th World Stroke Congress
Less wealthy countries struggle to meet greater need with far fewer resources.

Marijuana use might lead to higher risk of stroke, World Stroke Congress to be told
A five-year study of hospital statistics from the United States shows that the incidence of stroke has risen steadily among marijuana users even though the overall rate of stroke remained constant over the same period.

We need to talk about sexuality after stroke
Stroke survivors and their partners are not adequately supported to deal with changes to their relationships, self-identity, gender roles and intimacy following stroke, according to new research from the University of Sydney.

Standardized stroke protocol can ensure ELVO stroke patients are treated within 60 minutes
A new study shows that developing a standardized stroke protocol of having neurointerventional teams meet suspected emergent large vessel occlusion (ELVO) stroke patients upon their arrival at the hospital achieves a median door-to-recanalization time of less than 60 minutes.

Read More: Stroke News and Stroke Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.