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07 February 2019: Massive chemical libraries, and CRISPR-CasX

From Nature Podcast - This week, virtual drug discovery, and a new addition to the CRISPR toolkit.


Nature Podcast
The Nature Podcast brings you the best stories from the world of science each week. We cover everything from astronomy to neuroscience, highlighting the most exciting research from each issue of Nature journal. We meet the scientists behind the results and providing in-depth analysis from Nature's journalists and editors.

07 February 2019: Massive chemical libraries, and CRISPR-CasX
2019-02-06 10:01:15
This week, virtual drug discovery, and a new addition to the CRISPR toolkit.
24 minutes, 51 seconds


04 July 2019: Machine learning in materials science, and sand's sustainability
2019-07-03 10:01:30
This week, using an algorithm to find properties in materials science, and the global consequences of sand-mining. In this episode: 00:47 Predicting properties A word-association algorithm is reading millions of abstracts to discover new properties of materials.  Research article: Tshitoyan et al.; News and Views: Text mining facilitates materials discovery 08:28 Research Highlights Tiny robot-jellyfish, and genome mutation hot-spots.  Research Article:Multi-functional soft-bodied jellyfish-like swimming; Research Highlight:How DNA 'hotspots' snarl the search for cancer genes 10:48 Sand under strain Researchers warn that the mining of sand is unsustainable.  Comment:Time is running out for sand 15:44 News Chat The results of a bullying survey, and the spread of microbial disease through opioid use.  News: Germany's prestigious Max Planck Society conducts huge bullying survey; News: The US opioid epidemic is driving a spike in infectious diseases For information regarding your data privacy, visit acast.com/privacy


REBROADCAST: Nature PastCast, June 1876
2019-06-28 06:29:23
This year, Nature celebrates its 150th birthday. To mark this anniversary we're rebroadcasting episodes from our PastCast series, highlighting key moments in the history of science. According to the fables of early explorers, the gorilla was a terrible, man-eating monster. It was also thought to be man's closest relative in the animal kingdom. Naturally, scientists and the public alike wanted to see these fierce beasts for themselves. But in the mid-nineteenth century, as the evolution debate heated up, getting a live gorilla to Europe from Africa was extremely difficult. In 1876, the pages of Nature report the arrival in England of a young specimen. This episode was first broadcast in June 2013. For information regarding your data privacy, visit acast.com/privacy


27 June 2019: Callused feet, and protein-based archaeology
2019-06-26 10:01:56
This week, how wearing shoes might affect foot sensitivity, and uncovering history with ancient proteins. For information regarding your data privacy, visit acast.com/privacy


20 June 2019: Non-native species, and a blood-inspired robot battery
2019-06-19 10:01:58
This week, what makes birds invasive and a robotic fish powered by a blood-like battery. For information regarding your data privacy, visit acast.com/privacy


13 June 2019: Mighty magnets, and aerosols in the atmosphere
2019-06-12 10:01:57
This week, a record-breaking magnetic field, and aerosols' potential effects on the atmosphere. In this episode: 00:45 Making massive magnets Researchers have created the world's strongest direct current magnetic field. 08:38 Research Highlights Macaques' musicality and human consumption of microplastics. 10:55 Aerosols' impacts on the climate There's a still a lot to learn about how aerosols affect the climate. 17:03 News Chat The launch of an X-ray space telescope, and a Russian researcher's plans to CRISPR-edit human embryos.


06 June 2019: Microbes modifying medicine and kickstarting plate tectonics
2019-06-05 10:01:23
This week, how gut microbes might be affecting drugs, and a new theory on the beginning of plate tectonics. In this episode: 00:45 Microbes metabolising drugs Researchers are investigating whether the gut microbiota can alter the activity of medicinal drugs. Research article: Zimmermann et al.   06:40 Research Highlights Elephants counting with smell, and audio activity monitoring. Research Highlight: Elephants have a nose for portion size Research Highlight: Deep learning monitors human activity based on sound alone 08:57 The origin of plate tectonics? A new theory suggests that sediment may have lubricated the Earth's tectonic plates, allowing them to move. Research article: Sobolev and Brown News and Views: Earth's evolution explored   14:14 News Chat Scientists protest in Hungary, and a trial of a new post-review process to test reproducibility. News: Hungarians protest against proposed government takeover of science News: Reproducibility trial publishes two conclusions for one paper


REBROADCAST: Nature PastCast May 1983
2019-05-31 08:01:10
This year, Nature celebrates its 150th birthday. To mark this anniversary we're rebroadcasting episodes from our PastCast series, highlighting key moments in the history of science. The discovery of the ozone hole in the mid-1980s was a shock. Scientists suspected that man-made gases called CFCs were damaging the ozone layer, but they didn't expect to see such a dramatic decline. Nor did they expect the discovery to be made by a small group of British scientists in Antarctica. In this podcast, we hear from the 'little voice' in the background whose persistence led to the reporting of the reduced ozone in Nature in May 1985. But how did it become known as the 'ozone hole'? And what lessons are there for climate change scientists today?


30 May 2019: Cold fusion, gender parity in universities, and studying wildfires
2019-05-30 04:01:26
This week, looking back at cold fusion, a ranking of gender balance in universities, and measuring the impact of wildfires.


23 May 2019: Pre-industrial plankton populations, European science, and ancient fungi.
2019-05-22 10:01:53
This week, how climate change has affected plankton, the future of European science, and evidence of an ancient fungus.


16 May 2019: Recoding genomes, and material from the Moon's far side
2019-05-15 10:01:32
This week, rewriting the script of life, and a trip to the far side of the Moon.


09 May 2019: Urban vs Rural BMI, and the health of rivers
2019-05-08 10:01:08
This week, body mass increases around the world, and river connections in decline.


02 May 2019: China's growing science network, and talking brain signals
2019-05-01 10:34:11
This week, China's Belt and Road Initiative, and translating brain patterns into speech.


REBROADCAST: Nature PastCast April 1953
2019-04-26 08:56:52
This year, Nature celebrates its 150th birthday. To mark this anniversary we're rebroadcasting episodes from our PastCast series, highlighting key moments in the history of science. Over 60 years ago, James Watson and Francis Crick published their famous paper proposing a structure for DNA. Everyone knows that story - but fewer people know that there were actually three papers about DNA in that issue of Nature. In this podcast, first broadcast in April 2013, we uncover the evidence that brought Watson and Crick to their conclusion, discuss how the papers were received at the time, and hear from one scientist who was actually there: co-author of one of the DNA papers, the late Raymond Gosling.


25 April 2019: Tiny earthquakes, the genetics of height, and how US-China politics is affecting research
2019-04-25 03:40:33
This week we've got an extended News Chat between presenter Benjamin Thompson and Nature's European Bureau Chief Nisha Gaind. They discuss a new way to identify tiny earthquakes, new insights into the heritability of height, and how political tensions between the US and China are affecting scientists and research.


18 April 2019: Reviving brains, lightning, and spring books
2019-04-17 10:03:34
This week, restoring function in dead pig brains, spring science books, and the structure of lightning. If you have any questions about the partly-revived brains study, then the reporters at Nature are keen to answer them. You can submit them at the bottom of the article, here: https://www.nature.com/articles/d41586-019-01216-4  


Podcast Extra: The first image of a black hole
2019-04-11 12:06:13
This week, researchers released the first image of a black hole at the centre of the M87 galaxy. In this special News Chat, Nature reporter Davide Castelvecchi, who was at a press conference in Brussels where the image was announced, tells Benjamin Thompson about the image and what scientists are saying about it.


11 April 2019: Heart failure and vacuum field fluctuations.
2019-04-10 10:01:04
This week, a new mouse model for heart failure and characterising energy fluctuations in empty space.


04 April 2019: MDMA and the malleable mind, and keeping skin young
2019-04-03 10:01:14
This week, why MDMA could make social interactions more rewarding, and how your skin keeps itself youthful.


Backchat March 2019: Calls for a research moratorium, and the evolution of science reporting
2019-03-29 11:44:13
In this month's roundtable, our reporters discuss calls to pause heritable genome-editing research, and how science journalism has changed in the past 20 years.


28 March 2019: Human impacts on Mount Kilimanjaro, sex differences in pain, and a crystal-based cooling method
2019-03-27 11:01:11
This week, how humans are affecting Kilimanjaro's ecosystems, differences in pain based on biological sex, and refrigerating with crystals.


21 March 2019: Antibiotics in orchards, and rethinking statistical significance
2019-03-20 11:01:07
This week, a plan to spray antibiotics onto orange trees, and is it time to retire statistical significance?


REBROADCAST: Nature Pastcast March 1918
2019-03-15 08:16:08
This year, Nature celebrates its 150th birthday. To mark this anniversary we're rebroadcasting episodes from our Pastcast series, bringing to life key moments in the history of science. As the First World War draws to an end, astronomer Arthur Eddington sets out on a challenging mission: to prove Einstein's new theory of general relativity by measuring a total eclipse. The experiment became a defining example of how science should be done. This episode was first broadcast in March 2014.


14 March 2019: Ebola in DRC, a new HIV treatment, and the proposed US budget. 
2019-03-14 05:25:34
Instead of a regular edition of the Nature Podcast, this week we've got an extended News Chat between Benjamin Thompson and Amy Maxmen. They discuss the ongoing Ebola outbreak in DRC, an injectable treatment for HIV, and how the proposed US 2020 budget could affect science.


07 March 2019: Coastal carbon-sinks, mobile health, and Mileva Marić
2019-03-06 10:01:56
This week, wetlands' ability to store carbon, mobile health, and the story of Mileva Marić.


28 February 2019: Cuckoo parasitism, topological materials and cannabinoids in yeast.
2019-02-27 10:01:41
This week, the parenting strategies of a tropical cuckoo, increasing the number of topological materials, and growing cannabinoids in yeast.


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