Cancer Immunotherapy, Raccoons, Frog Calls. Dec 14, 2018, Part 1 from Science Friday

From Science Friday - For years, cancer treatment has largely involved one of three options—surgery, radiation, or chemotherapy. In recent years, however, a new treatment option, immunotherapy, has entered the playing field. It has become the first-line preferred treatment for certain cancers. Immunotherapy is a class of treatments that use some aspect of the body's own immune response to help battle cancer cells. There are several different approaches, each with their own advantages and weaknesses.This year, the 2018 Nobel Prize in Physiology or Medicine was awarded jointly to James P. Allison and Tasuku Honjo "for their discovery of cancer therapy by inhibition of negative immune regulation." The Nobel committee called their discoveries a landmark in our fight against cancer. Treatments based on their work are now in use against several forms of cancer, with many more trials underway. Still, the approach doesn't work in all cases, and researchers are working to try to better understand why. How do raccoons keep getting into people's trash? It might just be one of the greatest unsolved mysteries of our time. No matter what kind of fancy lid, bungee cord, or alarm system we use, somehow these masked creatures always find a way into our smelly garbage. But are they just dexterous or actually smart? Lauren Stanton, Ph.D. candidate in the Animal Behavior and Cognition Lab at the University of Wyoming, joins Ira to talk about testing the animal's smarts. City mouse and country mouse aren't just characters from stories—cities are unique ecosystems built by humans, and animals adapt when they move into urban areas. Researchers recently compared the calls of male túngara frogs in Panama that lived in the forest with those in the city. They found that the city frogs had more complex calls and that female frogs preferred these calls—but the less complex calls of country frogs made them easier to hide from predators. Biologist Alex Trillo, an author on the study, talks about the costs and benefits of changing calls for the túngara frog.
Cancer Immunotherapy, Raccoons, Frog Calls. Dec 14, 2018, Part 1
2018-12-14 13:57:47
For years, cancer treatment has largely involved one of three options—surgery, radiation, or chemotherapy. In recent years, however, a new treatment option, immunotherapy, has entered the playing field. It has become the first-line preferred treatment for certain cancers. Immunotherapy is a class of treatments that use some aspect of the body's own immune response to help battle cancer cells. There are several different approaches, each with their own advantages and weaknesses.This year, the 2018 Nobel Prize in Physiology or Medicine was awarded jointly to James P. Allison and Tasuku Honjo "for their discovery of cancer therapy by inhibition of negative immune regulation." The Nobel committee called their discoveries a landmark in our fight against cancer. Treatments based on their work are now in use against several forms of cancer, with many more trials underway. Still, the approach doesn't work in all cases, and researchers are working to try to better understand why. How do raccoons keep getting into people's trash? It might just be one of the greatest unsolved mysteries of our time. No matter what kind of fancy lid, bungee cord, or alarm system we use, somehow these masked creatures always find a way into our smelly garbage. But are they just dexterous or actually smart? Lauren Stanton, Ph.D. candidate in the Animal Behavior and Cognition Lab at the University of Wyoming, joins Ira to talk about testing the animal's smarts. City mouse and country mouse aren't just characters from stories—cities are unique ecosystems built by humans, and animals adapt when they move into urban areas. Researchers recently compared the calls of male túngara frogs in Panama that lived in the forest with those in the city. They found that the city frogs had more complex calls and that female frogs preferred these calls—but the less complex calls of country frogs made them easier to hide from predators. Biologist Alex Trillo, an author on the study, talks about the costs and benefits of changing calls for the túngara frog.

47 minutes, 39 seconds

More Episodes from Science Friday

Covering everything about science and technology -- from the outer reaches of space to the tiniest microbes in our bodies -- Science Friday is your source for entertaining and educational stories and activities. Each week, host Ira Flatow interviews scientists and inventors like Sylvia Earle, Elon Musk, Neil deGrasse Tyson, and more.

Tech Unions, Color Perception, Fish Vs Birds. Feb 19, 2021, Part 2
Reprogramming Labor In Tech More than 6,000 warehouse workers in Bessemer, Alabama are midway through voting on whether they should unionize. If the 'yes' votes win, it would be unprecedented for the company: The last time a unionization vote was held by Amazon's United States employees, back in...

Fauci On Vaccines and Variants, Mummy Mystery, Texas Power Grid Failure. Feb 19, 2021, Part 1
Fauci Says Majority Of U.S. Adults Likely To Be Vaccinated By Late Summer We're about a month shy of a big anniversary: one year since the World Health Organization officially labeled COVID-19 a pandemic. Since then, a lot has changed–and a lot has not. We have more information than ever about...

Fish Eye Secrets, Human Genome Project, Science Diction 'Mesmerize.' Feb 12, 2021, Part 2
Seeing The World Through Salmon Eyes The saying goes, "The eyes are the window to the soul." But for fish, the eyes are the window to the stomach.  As one California biologist recently learned, the eyes of Chinook salmon are like a tiny diet journal of everything it ate. But to read that journal,...

The Effectiveness Of Double-Masking, Mars Landing Preview. Feb 12, 2021, Part 1
Two Masks Are Better Than One Masks have been a big issue throughout the pandemic, from supply shortages to debates about when they should be required to be used. This week, the Centers for Disease Control and Prevention put out research and guidance on the effectiveness of double masking–wearing...

Four Lost Cities, Sourdough Microbiome, Queen Bees, Bison. Feb 5, 2021, Part 2
National Bison Range Returns To Indigenous Management Hundreds of years ago, tens of millions of bison roamed North America. They were an essential resource and cultural foundation for many Native American tribes. And by 1890, European colonists had hunted them nearly to extinction.  When President...

COVID Variants And Vaccines, U.S. Energy Justice. Feb 5, 2021, Part 1
Will Vaccines Work Against New Variants Of The Coronavirus? The rollout of COVID-19 vaccination programs around the world has been anything but smooth. Complicating the effort is the virus itself. The original coronavirus genome that the current vaccines were based on has mutated. Now, there are...

Medieval Bones, Vaccine Rollout, Florida Panthers. Jan 29, 2021, Part 2
A Skeletal Record Of Medieval England Society If you've ever fractured a bone, that skeletal trauma stays with you forever, even after it heals. So researchers across the pond are using bones from medieval times to put together a picture of what life was like. The bones in the study came from...

Your Questions About COVID-19 Vaccines Answered, Placenta Science. Jan 29, 2021, Part 1
Everything You Want To Know About COVID-19 Vaccines The U.S. has been vaccinating people against COVID-19 for a little over a month. While there have been plenty of hiccups, over 20 million people in the country have received at least one dose of either the Pfizer-BioNTech or the Moderna shots. For...

Orange Bat, Greenland Bacteria, COVID Anniversary, Alien Argument. Jan 22, 2021, Part 2
Orange Is The New Black–For Bats For a newly-described bat from West Africa, dubbed Myotis nimbaensis (mouse-eared bat from the Nimba Mountains), scientists are reaching for a different part of the color wheel. While Myotis does have some black on its body, the overwhelming majority of the...

Finding Lead Pipes Through Algorithm, How Soil Could Save The Planet. Jan 22, 2021, Part 1
After Flint's Crisis, An Algorithm Helps Citizens Find Lead Pipes It's been nearly seven years since the beginning of Flint, Michigan's water crisis, when high levels of lead from corroded lead pipes led to water shortages and health issues for city residents. Since then, many other cities around...

Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.