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Childhood methylphenidate treatment predicts antidepressant use during adolescence
A new, 12-year longitudinal study, which monitored 6,830 children from early childhood into adolescence, has shown that consistent treatment with MPH-based medications during childhood increases the risk of antidepressant use during adolescence. The study is the first of its kind to examine the connection between children diagnosed with ADHD and prescribed MPH between the ages of six and eight, and future dispensed prescriptions of antidepressants. (2019-03-27)

How genes affect tobacco and alcohol use
A new study gives insight into the complexity of genetic and environmental factors that compel some of us to drink and smoke more than others. (2019-02-21)

Brain protein mutation from child with autism causes autism-like behavioral change in mice
A de novo gene mutation that encodes a brain protein in a child with autism has been placed into the brains of mice. These mice then showed severe alterations of specific behaviors that closely resemble those seen in human autism spectrum disorder, or ASD. (2019-07-23)

New study: Children with autism may be over-diagnosed with ADHD
Pediatric researchers report that children with ASD may mistakenly be diagnosed with ADHD because they have autism-related social impairments rather than problems with attention. This is important for understanding what are the right services and treatments for a child. (2016-10-28)

Is ADHD really a sleep problem?
Around 75 percent of children and adults with attention deficit hyperactivity disorder (ADHD) also have sleep problems, but until now these have been thought to be separate issues. Now a in a pulling together of the latest research, Scientists are proposing of a new theory which says that much of ADHD may in fact be a problem associated with lack of regular circadian sleep. (2017-09-02)

Largest brain study of 62,454 scans identifies drivers of brain aging
In the largest known brain imaging study, scientists from Amen Clinics (Costa Mesa, CA), Google, John's Hopkins University, University of California, Los Angeles and the University of California, San Francisco evaluated 62,454 brain SPECT (single photon emission computed tomography) scans of more than 30,000 individuals from 9 months old to 105 years of age to investigate factors that accelerate brain aging. (2018-08-21)

Many NHS partnerships with drug companies are out of public sight
NHS organisations are entering into working partnerships with drug companies, but they are not making the details, and even existence, of many of these deals available to the public, reveals an investigation by The BMJ today (2019-03-27)

AI to help monitor behavior
Algorithms based on artificial intelligence do better at supporting educational and clinical decision-making, according to a new study. (2020-01-27)

The rules of the game for children with ADHD
Researchers use a game-based experiment to understand how children with ADHD react to changing situations. (2016-06-02)

Antipsychotic use in youths with ADHD is low, but still cause for concern
A new study eased fears about the proportion of youths with ADHD taking antipsychotic drugs, but still found that many prescriptions may be inappropriate. (2019-07-26)

First genetic map of the Attention Deficit Hyperactivity Disorder
An international study, focused on the analysis of the genome of more than 50,000 people worldwide, has identified twelve specific fragments of DNA related to the vulnerability of the attention deficit hyperactivity disorder (ADHD). The study has been published in the journal Nature Genetics, involves more than eighty authors. (2018-11-26)

Cycles of reward: New insight into ADHD treatment
Researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) in collaboration with scientists at the University of Otago and the University of Auckland in New Zealand, investigated the actions of the drug in rats. Using dopamine cell recordings, electrochemical monitoring and computer modeling, they discovered a type of feedback loop that modulates dopamine levels in the rats' brains in response to the drug. This regulatory process may shed light on methylphenidate's therapeutic properties in ADHD. (2019-10-30)

Common psychiatric disorders share an overlapping genetic risk
Investigators found that many common psychiatric disorders are deeply connected on a genetic level, sharing specific genetic risk factors, underscoring the need to recognize shared dimensions of brain dysfunction, and develop new treatment strategies. Results of this investigation have been published in the June 22, 2018 issue of the journal, Science. (2018-06-21)

Thinking outside the box: Adults with ADHD not constrained in creativity
People often believe those with Attention Deficit Hyperactivity Disorder face challenges that could hinder future employment, but a University of Michigan study found that adults with ADHD feel empowered doing creative tasks that could help them on the job. (2018-10-09)

Online parent training helps young kids with ADHD
Researchers at Lehigh University have discovered that brief online or in-person behavioral therapy for parents is equally effective in improving children's behavior and parental knowledge -- a potential game changer for parents strapped for time and access. They report these findings in a new paper published in The Journal of Clinical Child & Adolescent Psychology, 'Face-to-Face vs. Online Behavioral Parent Training for Young Children At-Risk for ADHD: Treatment Engagement and Outcomes.' (2017-10-03)

World's largest evidence review: Nutritional supplements for mental health
We've all heard that 'food is good for your mood'. Now a new study into mental health and nutrient supplementation has taken a leap forward by establishing the gold standard for which nutrients are proven to assist in the management of a range of mental health disorders. (2019-09-09)

Impacts of local exposure to fracking sites on Pennsylvania infants
Based on a decade of data from Pennsylvania, researchers report that babies born to mothers living within 1 kilometer of active 'fracking' wells are 25 percent more likely to exhibit low birth weight -- a risk factor for infant mortality, ADHD, asthma, and other negative outcomes. The results reflect a possible health consequence of exposure to fracking pollutants. To date, (2017-12-13)

Are traumatic brain injuries in kids associated with later ADHD?
Severe traumatic brain injury in children was associated with increased risk for later onset of attention-deficit/hyperactivity up to about seven years after injury. (2018-03-19)

What can Twitter reveal about people with ADHD?
People with attention-deficit/hyperactivity disorder tend to tweet using words like 'hate' or 'disappointed,' messages related to lack of focus, self-regulation, intention and failure and expressions of mental, physical and emotional exhaustion, according to research from the University of Pennsylvania. Better understanding this condition can help clinicians more effectively treat patients. (2017-11-13)

Study finds ADHD drugs are unlikely to cause cardiac damage in children who take them
The results of a long-term NIH-funded study published last month could allay concerns that ADHD drugs can cause cardiac damage in children. (2019-01-03)

U-M study highlights multiple factors of ADHD medication use
Youth who take Ritalin, Adderall or other stimulant medications for ADHD over an extended period of time early in life are no more at risk for substance abuse in later adolescence than teens without ADHD, according to a University of Michigan study. (2016-06-08)

Is there an association between more frequent use of digital media by teens and symptoms of ADHD?
Frequent use of digital media may be associated with the development of attention-deficit/hyperactivity disorder (ADHD) symptoms in adolescence but more research is needed to know if the association is causal. (2018-07-17)

Women with suspected HPV adverse effects more often suffered from psychiatric disorders
New research from Aarhus University shows that women who are referred to an HPV center more often have had psychiatric medicine prescribed or been hospitalized for psychiatric conditions up to five years before they received the vaccine. (2017-09-28)

Maternal smoking during pregnancy increases risk of ADHD among offspring up to 3-fold
The higher the cotinine levels were in the mother's blood during pregnancy, the greater was the child's risk of developing attention deficit hyperactivity disorder (ADHD) later in life, showed an epidemiological study conducted by the Research Centre for Child Psychiatry at the University of Turku, Finland. Globally, it is the first study in which the connection between fetal nicotine exposure and diagnosis of ADHD was shown by measuring cotinine levels from pregnant maternal serum specimens. (2019-02-26)

Brain wiring differences identified in children with conduct disorder
Behavioural problems in young people with severe antisocial behaviour -- known as conduct disorder -- could be caused by differences in the brain's wiring that link the brain's emotional centres together, according to new research led by the University of Birmingham. (2019-04-18)

Fruit flies help in the development of personalized medicine
It is common knowledge that there is a connection between our genes and the risk of developing certain diseases. In a study on fruit flies, researchers from Aarhus University and Aalborg University have found that gene mapping can also be used to predict response to a given treatment. This knowledge is crucial for the development of personalised medicine. (2019-10-09)

Young mums more likely to have kids with ADHD
Young mothers have a greater chance of having a child with attention deficit hyperactivity disorder (ADHD) according to new research from the University of South Australia. Exploring the genetic relationship between female reproductive traits and key psychiatric disorders, it found that the genetic risk of ADHD in children was strongly associated with early maternal age at first birth, particular for women younger than 20. (2019-10-23)

Large study finds higher rates of early substance use among children with ADHD
Children with ADHD engaged in substance use at a younger age and had a significantly higher prevalence of regular marijuana and cigarette use as adults. (2018-01-23)

Are gestational age at birth and symptoms of ADHD associated?
Early premature birth at less than 34 weeks was associated with symptoms of attention-deficit/hyperactivity disorder (ADHD) in preschool-age children and inattention symptoms in school-age children. (2018-06-25)

Attention deficit disorders could stem from impaired brain coordination
Researchers from Case Western Reserve University School of Medicine and colleagues have discovered how two brain regions work together to maintain attention, and how discordance between the regions could lead to attention deficit disorders, including schizophrenia, bipolar disorder, and major depression. (2018-04-05)

US poison control centers receive 29 calls per day about children exposed to ADHD medications
The study found that there were more than 156,000 calls to US Poison Control Centers regarding exposures to attention-deficit hyperactivity disorder (ADHD) medications among children and adolescents 19 years of age and younger from January 2000 through December 2014, averaging 200 calls each week or 29 calls per day. (2018-05-21)

First Trial Comparing Adderall To Ritalin For ADHD Shows It To Be Longer-Lasting, Equally As Effective
The first trial of comparable doses of Ritalin, the standard treatment for children with attention deficit/hyperactivity disorder (ADHD), and Adderall, another drug used to treat ADHD, has shown that Adderall lasts longer than Ritalin and is at least as effective. Results are reported by University at Buffalo researcher William R. Pelham in the April issue of Pediatrics. (1999-04-05)

Scientists discovered genes that contribute to the ADHD development
A team from I.M. Sechenov First Moscow State Medical University together with foreign colleagues analyzed the genomes of several families that have members with ADHD. The results have shown that all patients had specific features in certain genes. The identification of such patterns may help diagnose ADHD. The work was published in the Molecular Psychiatry journal. (2018-10-12)

Children with ADHD sleep both poorly and less
A new study from Aarhus University has now documented that there is some truth to the claim by parents of children with ADHD that their children have more difficulty falling asleep and that they sleep more poorly than other children. (2016-05-04)

Air pollution and poverty stack the deck for ADHD
Scientists at the Columbia Center for Children's Environmental Health (CCCEH) at the Mailman School of Public Health report the first evidence that prenatal exposure to polycyclic aromatic hydrocarbons (PAH) -- carcinogenic and neurotoxic combustion byproducts commonly found in urban air -- combines with material hardship to significantly increase ADHD symptoms in children. Results are online in the journal Environmental Research. (2017-10-04)

Estimates of ASD, ADHD risk in siblings born after older children with those disorders
Siblings born in a family after other children with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) were more likely to be diagnosed with the same disorder or the other disorder. (2018-12-10)

NIH study reveals differences in brain activity in children with anhedonia
Researchers have identified changes in brain connectivity and brain activity during rest and reward anticipation in children with anhedonia, a condition where people lose interest and pleasure in activities they used to enjoy. The study, by scientists at the National Institute of Mental Health (NIMH), part of the National Institutes of Health, sheds light on brain function associated with anhedonia and helps differentiate anhedonia from other related aspects of psychopathology. (2019-03-13)

Teen suicide: ADHD medication as prevention
Black-box warnings about the dangers of attention-deficit hyperactivity disorder (ADHD) medications are confusing and could have serious consequences for the risk of youth suicide, according to researchers at the Institut universitaire en santé mentale de Montréal (CIUSSS de l'Est-de-l'Île-de-Montréal) and the University of Montreal. (2016-02-01)

Steep rise in self-poisonings in children and adolescents
Self-harm from self-poisoning in children and adolescents is not only increasing but starting at a younger age, finds new research by University of Sydney and the NSW Poisons Information Centre. The study found there were more than 33,500 self-poisonings in young people in Australia from 2006 - 2016, with a 98 per cent increase over this time. (2019-02-20)

Exposure to air pollution in pregnancy does not increase symptoms of attention-deficit
A study of 30,000 children from seven European countries found no association between prenatal exposure to air pollution and symptoms of attention-deficit and hyperactivity. (2018-06-25)

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