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Surgeons find better ways to treat nerve compression disorder that can sideline athletes
Two new studies from Washington University School of Medicine in St. Louis suggest ways to improve surgical treatment for a debilitating condition caused by compressed nerves in the neck and shoulder. (2013-02-07)

Combating wear and tear
A team of researchers led by University of Utah bioengineering professors has discovered that damage to collagen, the main building block of all human tissue, can occur much earlier at a molecular level from too much physical stress. This could be especially helpful for some who want to know earlier if they are developing diseases such as arthritis or for athletes who want to know if repeated stress on their bodies is taking a toll. (2017-03-22)

'Tommy John' elbow reconstruction 95 percent successful with grown teen pitchers, study says
A new study presented today at the American Orthopaedic Society for Sports Medicine's Specialty Day in New Orleans, found that 95 percent of skeletally mature high school pitchers were satisfied with their (2010-03-13)

Mayo Clinic researchers find evidence for traumatic cause of carpal tunnel syndrome
New Mayo Clinic research suggests that a shearing injury of the tissue that lines the tendons within the carpal tunnel may cause carpal tunnel syndrome, a debilitating condition of the wrist and hand. (2006-11-09)

A novel strategy to potentially reduce breast cancer bone metastasis
Uncovering a novel mechanism that promotes growth of breast cancer bone metastasis has revealed a potential Achilles' heel for these cancer cells. (2018-11-12)

Tendon stem cells could revolutionize injury recovery
The buildup of scar tissue makes recovery from torn rotator cuffs, jumper's knee, and other tendon injuries a painful, challenging process, often leading to secondary tendon ruptures. New research reveals the existence of tendon stem cells that could potentially be harnessed to improve tendon healing and even to avoid surgery. (2019-11-25)

Making some of the world's most durable materials corrosion-resistant
Borides are among the hardest and most heat-resistant substances on the planet, but their Achilles' Heel, like so many materials', is that they oxidize at high temperatures. Researchers from Drexel University, Linkoping University in Sweden and Imperial College London have produced an aluminum-layered boride whose unique behavior at high temperatures keeps it one step ahead of nature's slow march toward high- temperature chemical degradation. (2016-05-25)

Virulence switch in 'Iraqibacter': potential Achilles heel?
Microbiologists have identified a component of a genetic switch, which they call a potential 'Achilles' heel,' for a type of bacteria often associated with wounded warriors. The switch makes it possible for Acinetobacter baumannii to change between a virulent, hardy form and an avirulent form that is better at surviving at lower temperatures outside a host. Defining the switch could map out targets for new antibiotics. (2018-04-23)

Helping hearts, spinal cords and tendons heal themselves
Queen's University Brian Amsden is hoping that in about 10 years a tendon, spinal cord or heart valve will be able to regenerate itself after an injury or disease. The chemical engineering professor, along with scientists from the University of Western Ontario and University of Toronto, is currently trying to develop microscopic polymer fibers to help rebuild human tissue and speed the healing process. (2010-06-08)

New stem cell technology developed at Hebrew University
A novel technology involving use of stem cells, developed by Hebrew University of Jerusalem researchers, has been applied to provide better and rapid healing for patients suffering from complicated bone fractures. (2009-11-30)

Gout isn't always easy to prove: CT scans help catch cases traditional test misses
Gout is on the rise among US men and women, and this piercingly painful and most common form of inflammatory arthritis is turning out to be more complicated than had been thought. The standard way to check for gout is by drawing fluid or tissue from an affected joint and looking for uric acid crystals, a test known as a needle aspirate. (2014-03-26)

Early rotator cuff surgery yields good long-term outcomes
Early surgery to repair tears of one of the shoulder rotator cuff muscles provides lasting improvement in strength, function, and other outcomes, reports a study in the Aug. 16, 2017 issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer. (2017-08-17)

IAU names dwarf planet Eris
The International Astronomical Union announces the names Eris for the dwarf planet provisionally named 2003 UB313 and Dysnomia for its moon. (2006-09-14)

Osteoporosis drug improves healing after rotator cuff surgery
Tears in the shoulder's rotator cuff, a common sports injury, are painful and restricting. New research shows an approved therapy for osteoporosis, Forteo, may speed healing and improve patient outcomes, according to a preliminary study from Hospital for Special Surgery in New York. (2010-03-10)

Achilles heel of tumor cells
In almost all cases of colon cancer, a specific gene is mutated -- this offers opportunities to develop broadly effective therapeutic approaches. Research teams in Würzburg have taken this a step further. (2019-11-05)

Platelet-rich plasma: Does it work?
According to a new study in the October issue of the Journal of the American Academy of Orthopaedic Surgeons, early outcomes of PRP appear promising; however, larger clinical studies are still needed to determine the benefits of its use. (2009-10-01)

New model mimics human tumors for accurate testing of cancer drugs
Walter and Eliza Hall Institute researchers have genetically engineered a new laboratory model that enables accurate testing of anti-cancer drugs by mimicking the complexity of human cancers. Using this advanced model, researchers will be able to discover the safest and most effective ways to use promising drugs called MCL-1 inhibitors in the clinic. (2018-10-11)

Controlling deadly malaria without chemicals
Scientists have finally found malaria's Achilles' heel, a neurotoxin that isn't harmful to any living thing except Anopheles mosquitoes that spread malaria. (2019-06-28)

Chronic ankle pain may be more than just a sprain
Ankle sprains are a common injury after a fall, sudden twist or blow to the ankle joint. (2009-05-01)

Cancer's dangerous renovations to our chromosomes revealed
Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, new research reveals. (2020-10-27)

Researchers engineer antibody that acts against multiple SARS-like viruses
Researchers have engineered an antibody that neutralizes SARS-CoV-2 with a potency that 'rivals' current lead SARS-CoV-2 clinical neutralizing antibodies, and that also broadly neutralizes a range of clade 1 sarbecoviruses. (2021-01-25)

Study finds being in a good mood for your flu jab boosts its effectiveness
New research by a team of health experts at the University of Nottingham has found evidence that being in a positive mood on the day of your flu jab can increase its protective effect. (2017-09-25)

Searching for better treatments for irritated tendons
Researchers learn what makes tendons fray in old age, knowledge that could help develop better treatments for tendinosis and regrow damaged tissue. (2019-04-02)

The Lancet: Nerve transfer surgery restores hand function and elbow extension in 13 young adults with complete paralysis
Nerve transfer surgery has enabled 13 young adults with complete paralysis to regain movement and function in their elbows and hands, according to the largest case series of this technique in people with tetraplegia (paralysis of both the upper and lower limbs), published in The Lancet. (2019-07-04)

Findings add to evidence of association between Zika virus and Guillain-Barré syndrome
An examination of cases of Guillain-Barré syndrome in Puerto Rico identified Zika virus infection as a risk factor, according to a study published by JAMA. (2017-10-17)

Commonly used strategy for website protection is not waterproof
Cloud-based security providers commonly use DNS redirection to protect customers' websites. The success of this strategy depends on shielding the website's original IP address. Computer scientists from KU Leuven, Belgium, and digital research center iMinds have now revealed that the IP address can be retrieved in more than 70 percent of the cases. This means that the DNS redirection security mechanism can easily be bypassed. (2016-04-12)

Elastic slingshot powers snipefish feeding
The snipefish, an ocean-dwelling relative of the seahorse, has a very long, skinny snout ending in a tiny mouth. A recent study by UC Davis graduate student Sarah Longo shows that snipefish feed with an elastic-boosted head flick at almost unprecedented speed. (2018-07-23)

MIT: New tissue scaffold regrows cartilage and bone
MIT engineers and colleagues have built a new tissue scaffold that can stimulate bone and cartilage growth when transplanted into the knees and other joints. The scaffold, which recently went into clinical trials, could offer a potential new treatment for sports injuries and other cartilage damage, such as arthritis. (2009-05-11)

How to build a bio-bot: Researchers share design and development of biological machines
Creating tiny muscle-powered robots that can walk or swim by themselves -- or better yet, when prompted -- is more complicated than it looks. Rashid Bashir and Taher Saif of the University of Illinois will speak on the design and development of walking and swimming bio-bots at the annual meeting of the American Association for the Advancement of Science. (2017-02-18)

Researchers quantify in high speed a viper's strike in nature for the first time
The antagonistic predator-prey relationship is of interest to evolutionary biologists because it often leads to extreme adaptations in both the predator and prey. One such relationship is seen in the rattlesnake-kangaroo rat system. Biologist Timothy Higham at the University of California, Riverside and colleagues have captured in high speed (500 frames per second) a rattlesnake trying to capture a kangaroo rat. (2017-01-13)

Corticosteroids aid healing -- if the timing is right
A corticosteroid can improve the healing of damaged tendons, but it must be given at the right time, according to a new study from Linköping University in Sweden. In rats, the tendon became twice as strong. The results are presented in the journal Scientific Reports. (2017-10-17)

Potential new therapy takes aim at a lethal esophageal cancer's glutamine addiction
Medical University of South Carolina investigators have exploited a metabolic quirk of certain cancers known as glutamine addiction to identify a potential new therapy for esophageal cancer. After characterizing the pathway involved in cancer progression, they tested a new combination treatment in both cells and animal models, with promising results. The next step is to secure funding to bring the new combination regimen to clinical trial. Their findings are reported in Nature Communications. (2019-05-20)

Study finds Ponseti method of clubfoot correction
Clubfoot affects one in a thousand babies born in the United States, but with proper corrective treatment and follow-up, infants born with clubfoot can have feet compatible with an active, normal lifestyle. A new study in the February 2010 issue of the Journal of Bone and Joint Surgery compared two common treatment options for clubfoot -- Ponseti method and surgical treatment. (2010-02-01)

Regenerative medicine improves strength and function in severe muscle injuries
Patients with severe muscle loss surgically implanted with bioscaffolds derived from pig tissue showed significant improvement in strength and range of motion, as well as evidence for skeletal muscle regeneration. (2016-07-21)

Nano-sandwiching improves heat transfer, prevents overheating in nanoelectronics
Sandwiching two-dimensional materials used in nanoelectronic devices between their three-dimensional silicon bases and an ultrathin layer of aluminum oxide can significantly reduce the risk of component failure due to overheating, according to a new study published in the journal of Advanced Materials led by researchers at the University of Illinois at Chicago College of Engineering. (2018-09-12)

Study points way to possible new treatment for ligament injuries
A new exosomes study released in STEM CELLS may lead to future treatment for ligament injuries. (2020-11-03)

One-third of NFL players with Achilles tendon injuries sidelined
More than a third of National Football League players who sustained an Achilles tendon injury were never able to return to professional play according to research in the current issue of Foot & Ankle Specialist (published by SAGE). The injured players who did return to active play averaged a 50 percent reduction in their power ratings. (2010-01-11)

New radio-frequency technique for knee injuries
The application of a new technique for injuries of the cruciate ligament in the knee, involving the use of bipolar radio-frequency plus heat, has proved to be 90% effective in cases and shortens the recovery time of the patient. This project has received the National Prize for Research into Sports Medicine, awarded annually by the University of Oviedo. (2005-02-24)

User-Friendly Brace Helps Paraplegics To Walk
Dutch rehabilitation technologists have developed an orthopedic brace which makes it possible for paraplegics to carry out all kinds of everyday activities again. The brace is more versatile and easier to transport than previous models. It also allows the patient to bend his knees. The device was developed by a team from Twente University of Technology and 'Het Roessingh rehabilitation centre in Enschede. Funding was provided by the Netherlands NWO- Technology Foundation (STW). (1998-03-05)

Scientists uncover a deadly 'addiction' in esophageal cancer
Scientists have discovered a new way of attacking esophageal cancer cells that could make use of an existing drug in a new approach to treatment. Their study discovered a genetic weakness or 'Achilles' heel' in esophageal cancer cells that makes them particularly sensitive to a drug called ibrutinib which is already used to treat blood cancer. (2017-08-22)

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