Popular Amino Acids News and Current Events

Popular Amino Acids News and Current Events, Amino Acids News Articles.
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Not silent at all
The so-called 'silent' or 'synonymous' genetic alterations do not result in altered proteins. But they can nevertheless influence numerous functions of the cell and thus also disease processes. Scientists from the German Cancer Consortium, German Cancer Research Center, and the University of Freiburg have now created a comprehensive database of all synonymous mutations ever found in cancer. This is a 'reference book' that provides cancer researchers with all available information on each of these supposedly 'silent' mutations at a glance. (2019-06-12)

Following the light
Considering that light is the driving force behind the growth and productivity of reef ecosystems, scientists are interested in understanding the relationship between primary productivity and varying light conditions. In a recent PLoS ONE paper, postdoctoral researcher Yvonne Sawall and her advisor, associate scientist Eric Hochberg (both at the Bermuda Institute of Ocean Sciences) present evidence that reefs optimize their photosynthetic capacities to prevailing environmental conditions, such as general availability of light, nutrients, and temperature. (2019-02-05)

Big data studies scrutinize links between fatty liver disease and how cells make energy
Three recent studies investigate changes in mitochondria, the cell's energy producers, as fatty liver disease (NAFLD) progresses to steatohepatosis (NASH). The first two studies illuminate how mitochondrial energy production stutters and fails; the third describes how changes to the liver during disease progression affect the organ's use of nutrients to produce energy. (2018-09-14)

Folding revolution
A Harvard Medical School scientist has used a form of artificial intelligence known as deep learning to predict the 3D structure of effectively any protein based on its amino acid sequence. This new approach for computationally determining protein structure achieves accuracy comparable to current state-of-the-art methods but at speeds upward of a million times faster. (2019-04-17)

Tipping the scales
Human cells have a sophisticated regulatory system at their disposal: labeling proteins with the small molecule ubiquitin. In a first, a team from the Technical University of Munich (TUM) has succeeded in marking proteins with ubiquitin in a targeted manner, in test tubes as well as in living cells. The procedure opens the door to exploring the inner workings of this vital regulatory system. (2019-04-03)

Just add water
Chemists uncover a mechanism behind doping organic semiconductors (2019-09-16)

Study shows high phenolic acid intake -- associated with a healthy diet -- is associated with reduced breast cancer risk
New research presented at this year's European Congress on Obesity (ECO) in Glasgow, Scotland (April 28-May 1) shows that a high intake of phenolic acids -- associated with a healthy diet -- is associated with a decreased risk of postmenopausal breast cancer. The study is by Andrea Romanos Nanclares, University of Navarra, Pamplona, Spain, and colleagues. (2019-04-30)

Texas A&M AgriLife study shows BPA risk factor for inflammatory bowel disease
A recent study in a preclinical model of inflammatory bowel disease shows dietary exposure to bisphenol-A, or BPA, found in polycarbonate plastics and epoxy resins, can increase mortality and worsen its symptoms. (2018-07-05)

Whole eggs better for muscle building and repair than egg whites, researchers find
People who consume 18 grams of protein from whole eggs or from egg whites after engaging in resistance exercise differ dramatically in how their muscles build protein, a process called protein synthesis, during the post-workout period, researchers report in a new study. Specifically, the post-workout muscle-building response in those eating whole eggs is 40 percent greater than in those consuming an equivalent amount of protein from egg whites, the team found. (2017-12-20)

Genetically boosting the nutritional value of corn could benefit millions
Rutgers scientists have found an efficient way to enhance the nutritional value of corn -- the world's largest commodity crop -- by inserting a bacterial gene that causes it to produce a key nutrient called methionine, according to a new study. (2017-10-09)

Will supplements help your workout or diet routine?
The new year is a time to set new goals, and for many people this means losing weight and improving fitness. Many people may turn to dietary supplements for a boost to their routines. To help cut the confusion, the Office of Dietary Supplements (ODS) at the National Institutes of Health has two new resources to help people understand what is known about the effectiveness and safety of many ingredients in dietary supplements promoted for fitness and weight loss. (2018-01-24)

University of Alberta researchers discover new biomarker for rare autoimmune disease
University of Alberta researchers have identified a unique biological marker that can be used to identify the presence of the rare autoimmune disease myasthenia gravis, predict the course of the disease and identify new, personalized treatments. (2019-08-29)

Hydrogen bonds directly detected for the first time
For the first time, scientists have succeeded in studying the strength of hydrogen bonds in a single molecule using an atomic force microscope. Researchers from the University of Basel's Swiss Nanoscience Institute network have reported the results in the journal Science Advances. (2017-05-12)

New link between gut bacteria and obesity
Researchers at Lund University in Sweden have discovered a new link between gut bacteria and obesity. They found that certain amino acids in our blood can be connected to both obesity and the composition of the gut microbiome. (2018-02-23)

Your stomach bacteria determines which diet is best for weight reduction
New research enables 'tailored' diet advice -- based on our personal gut microbiome -- for persons who want to lose weight and reduce the risk of disease. Systems biologists at Chalmers University of Technology have for the first time successfully identified in detail how some of our most common intestinal bacteria interact during metabolism. (2015-09-10)

Novel technique helps ID elusive molecules
Stuart Lindsay, a researcher at Arizona State University's Biodesign Institute, has devised a clever means of identifying carbohydrate molecules quickly and accurately. The results of his research, which appear in the current issue of Nature Communications, pave the way for a new generation of analytic tools capable of ferreting out carbohydrates for diagnosis and eventual treatment of many diseases. (2016-12-21)

Unlocking the mystery of pollen tube guidance
Pollen tube guidance towards the ovule is an important step for fertilization in flowering plants. In order for this to happen, a pollen tube attractant peptide LURE guides the pollen tube precisely to the ovule. An international team of plant biologists at Nagoya University and Tsinghua University has succeeded in analyzing for the first time, the crystal structure of LURE bound to its receptor protein PRK6. (2017-12-29)

Biophysics: Bacterial adhesion in vitro and in silico
Ludwig-Maximilians-Universitaet in Munich researchers have characterized the physical mechanism that enables a widespread bacterial pathogen to adhere to the tissues of its human host. (2018-03-29)

Interrogating proteins
Scientists from the University of Bristol have designed a new protein structure, and are using it to understand how protein structures are stabilized. (2017-05-22)

Critical Materials Institute develops new acid-free magnet recycling process
A new rare-earth magnet recycling process developed by researchers at the Critical Materials Institute dissolves magnets in an acid-free solution and recovers high purity rare earth elements. (2017-09-07)

Russian chemists discovered a surprising effect of a well-known leukemia drug
Researchers from RUDN University and Institute of Biomedical Chemistry of the Russian Academy of Sciences have identified an alternative mechanism for the effective antitumor drug -- an enzyme called L-asparaginase. Some isoenzymes of L-asparaginase block the growth of telomeres (region of repetitive nucleotide sequences at each end of a chromosome) on DNA molecules, and this limits the number of divisions of a cancer cell. This effect is reported in the Biochemical and Biophysical Research Communications. (2017-11-10)

Microbial fuel cell converts methane to electricity
Transporting methane from gas wellheads to market provides multiple opportunities for this greenhouse gas to leak into the atmosphere. Now, an international team of researchers has taken the first step in converting methane directly to electricity using bacteria, in a way that could be done near the drilling sites. (2017-05-17)

Choose Omega-3s from fish over flax for cancer prevention, study finds
Omega-3s from fish pack a stronger punch than flaxseed and other oils when it comes to cancer prevention, according to a first-ever University of Guelph study. (2018-01-26)

Bitter rapeseed
Rapeseed doesn't just contain oil but high-quality protein, too. However, protein extracts from rapeseed have an intense, bitter off-taste. A team led by food chemist Thomas Hofmann has now identified the substance that is pivotal for the bitter taste. This is a first step towards developing rapeseed for the human protein supply. (2019-01-31)

Walnuts impact gut microbiome and improve health
Diets rich in nuts, such as walnuts, have been shown to play a role in heart health and in reducing colorectal cancer. According to a new study from the University of Illinois, the way walnuts impact the gut microbiome -- the collection of trillions of microbes or bacteria in the gastrointestinal tract -- may be behind some of those health benefits. (2018-05-03)

Proteins that can take the heat
Ancient proteins may offer clues on how to engineer proteins that can withstand the high temperatures required in industrial applications, according to new research published in the Proceedings of the National Academy of Sciences. (2017-03-30)

Systems biology approach identifies nutrient regulation of biological clock in plants
Using a systems biological analysis of genome-scale data from the model plant Arabidopsis, an international team of researchers identified that the master gene controlling the biological clock is sensitive to nutrient status. The study will appear in the latest issue of the Proceedings of the National Academy of Sciences. (2008-03-14)

New form of autism found
Autism spectrum disorders (ASD) affect around one percent of the world's population and are characterized by a range of difficulties in social interaction and communication. In a new study published in Cell today, a team of researchers led by Gaia Novarino, Professor at the Institute of Science and Technology Austria (IST Austria), has identified a new genetic cause of ASD. (2016-12-01)

A unique amino acid for brain cancer therapy
Researchers discover potential application of amino acid taurine in photodynamic therapy for brain cancer. (2017-06-23)

A new tool to decipher evolutionary biology
A new bioinformatics tool to compare genome data has been developed by teams from the Max F. Perutz Laboratories, a joint venture of the University of Vienna and the Medical University of Vienna, together with researchers from Australia and Canada. The program called 'ModelFinder' uses a fast algorithm and allows previously not attainable new insights into evolution. The results are published in the influential journal Nature Methods. (2017-05-09)

Successful synthesis of gamma-lactam rings from hydrocarbons
IBS scientists have designed a novel strategy to synthesize ring-shaped cyclic molecules, highly sought-after by pharmaceutical and chemical industries, and known as gamma-lactams. This study describes how these five-membered rings can be prepared from inexpensive and readily available feedstock hydrocarbons, as well as from complex organic molecules, such as amino acids and steroids. (2018-03-01)

En route to custom-designed natural products
Microorganisms often assemble natural products similar to industrial assembly lines. Certain enzymes, non-ribosomal peptide synthetases (NRPS) play a key role in this process. Biotechnologists at Goethe University have now been able to discover how these enzymes interact with each other. This brings them one step closer to their goal of engineering the production of such peptide natural products. (2018-10-19)

A cluster of mutations in neurofibromatosis is important risk factor for severe symptoms
Research led by Ludwine Messiaen shows that missense mutations in a cluster of just five codons in the NF1 gene are an important risk factor for severe symptoms of the genetic disease neurofibromatosis type 1. Such information is vital to help guide clinical management and genetic counseling in this complex disease, and it shows a potential need for increased disease surveillance of patients with missense mutations in that cluster -- specifically, codons 844 to 848. (2017-12-28)

Polyunsaturated fatty acids linked to reduced allergy risk
New research from Karolinska Institutet in Sweden reveals that high levels of polyunsaturated fatty acids in children's blood are associated with a reduced risk of asthma or rhinitis at the age of 16 years. The study is published in The Journal of Allergy and Clinical Immunology. (2017-12-05)

Scientists create complex transmembrane proteins from scratch
Molecular engineers have now show that it is possible to build complex, custom-designed transmembrane proteins from scratch. In the living world, transmembrane proteins naturally occur embedded in the membranes of cells and cellular organelles. They are essential for a number of functions, such as movement of signals or substances from inside or outside a living cell. The ability to design synthetic proteins to span membranes could allow scientists to build ones that can perform specific, useful tasks. (2018-03-01)

Microbiome differences between urban and rural populations start soon after birth
An analysis comparing the intestinal microbiomes of both infants and adults living in rural and urban areas of Nigeria has revealed that not only are there many differences in adults living in subsistence environments versus urban ones but also that these variations begin at a very young age. The study appears June 5 in the journal Cell Reports. (2018-06-05)

Study reveals novel biomarkers for future dementia risk
Sudha Seshadri, M.D., founding director of the Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases at UT Health San Antonio, is co-leader and senior author on research announced March 6 that identifies novel biomarkers of risk for future dementia. (2018-03-06)

Bionic bacteria may help fight disease and global warming
A strain of genetically enhanced bacteria developed by researchers at the Salk Institute for Biological Studies may pave the way for new synthetic drugs and new ways of manufacturing medicines and biofuels, according to a paper published September 18 in Nature Chemical Biology. (2011-09-21)

Potential new way to limit antibiotic resistance spreading
One of the biggest current threats to global health is the rise of multi-drug resistant bacteria, caused by the spreading of antibiotic resistance amongst them. In an attempt to help fight this threat, EMBL researchers have unraveled the molecular basis of a major antibiotic resistance transfer mechanism. They also developed molecules and a proof-of-principle for blocking this transfer. Cell publishes their results on March 15. (2018-03-15)

Metabolism gives a boost to understanding plant and animal nutrient evolution
In the advanced online edition of Molecular Biology and Evolution, authors Maurino, et. al., explore the evolution of a family of enzymes, called 2-hydroxy acid oxidase, or 2-HAOX, that break down fats in both plant and animals. Their results show how plants and animals have adapted differently to similar environmental conditions in order to meet their energy needs. (2014-02-14)

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