Popular Antibiotic News and Current Events

Popular Antibiotic News and Current Events, Antibiotic News Articles.
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Know your enemy
Antibiotic resistance in bacteria is a growing global health crisis. Now, new research provides crucial details on bacterial defenses and how we could undermine them. (2018-10-09)

Toxins from one bacterial species contribute to genetic diversity of others
A toxin produced by bacteria as a defence mechanism causes mutations in target bacteria that could help them survive. (2021-02-23)

How bacteria hunt other bacteria
A bacterial species that hunts other bacteria has attracted interest as a potential antibiotic, but exactly how this predator tracks down its prey has not been clear. A Biophysical Journal study reveals that the bacterial predator Bdellovibrio bacteriovorus homes in on its target by taking advantage of fluid forces generated by its own swimming movements and those of its prey. These bring the bacteria in close proximity, giving BV a greater chance of successful attack. (2017-03-28)

Bacteria take a deadly risk to survive
Bacteria need mutations -- changes in their DNA code -- to survive under difficult circumstances. When necessary, they can even mutate at different speeds. This is shown in a recent study by the Centre of Microbial and Plant Genetics at KU Leuven (University of Leuven), Belgium. The findings open up various new avenues for research, ranging from more efficient biofuel production methods to a better treatment for bacterial infections and cancer. (2017-05-02)

Novel device and staff education lead to lower blood culture contamination rates
A Medical University of South Carolina study found that use of a mechanical initial specimen diversion device (ISDD®) and staff education led to a nearly four-fold decrease in contaminated blood cultures that was sustained over 20 months. (2018-01-24)

Scientists develop new drug treatment for TB
Scientists at The University of Manchester have developed the first non-antibiotic drug to successfully treat tuberculosis in animals. The team hope the compound -developed after 10 years of painstaking research will be trialled on humans within three to four years. (2018-09-11)

Bacteria might help other bacteria to tolerate antibiotics better
A new paper by the Dynamical Systems Biology lab at UPF shows that the response by bacteria to antibiotics may depend on other species of bacteria they live with, in such a way that some bacteria may make others more tolerant to antibiotics. (2020-03-12)

Last-line antibiotics are failing
The ECDC's latest data on antimicrobial resistance and consumption shows that in 2015, antibiotic resistance continued to increase for most bacteria and antibiotics under surveillance. Antibiotic consumption in hospitals significantly increased in several EU Member States however, antibiotic consumption in the community decreased in six EU Member States. It is worrying that we see increased resistance to last-line antibiotics, but we still have time to turn the tide and ensure that antibiotics remain effective. (2016-11-18)

Case Western Reserve researchers cure drug-resistant infections without antibiotics
Biochemists, microbiologists, drug discovery experts and infectious disease doctors have teamed up in a new study that shows antibiotics are not always necessary to cure sepsis in mice. Instead of killing causative bacteria with antibiotics, researchers treated infected mice with molecules that block toxin formation in bacteria. Every treated mouse survived. The breakthrough study, published in Scientific Reports, suggests infections in humans might be cured the same way. (2018-10-17)

Metagenomic analysis software reveals new causes of superbug emergence
Researchers from ITMO University and Center of Physical and Chemical Medicine developed an algorithm capable of tracking the spread of antibiotic resistance genes in gut microbiota DNA and revealed additional evidence of resistance genes transfer between different bacterial species. The method can not only contribute to the development of effective therapy schemes, but also curb the spread of superbugs. The results of the research were published in 'Bioinformatics' journal. (2017-11-09)

Study reveals benefits of having GPs in Emergency Departments
A new study from the University of Liverpool provides evidence that locating a General Practitioner (GP) in a hospital emergency department (ED) can reduce waiting times and admissions, but may increases antibiotic prescribing. (2017-10-06)

Research paves the way for treatment strategies of multidrug-resistant chronic infections
A new study published in Cell Press finds that antibiotic treatment of chronic infections can be optimized by targeting vulnerabilities of antibiotic-resistant pathogens paving the way for more effective treatment strategies. (2018-01-05)

Antibiotics may impact cancer treatment efficacy
There is mounting laboratory evidence that in the increasingly complex, targeted treatment of cancer, judicious use of antibiotics also is needed to ensure these infection fighters don't have the unintended consequence of also hampering cancer treatment, scientists report. (2018-03-02)

Preserving the power of antibiotics
News release describes efforts to address inappropriate antibiotic prescribing in emergency departments and urgent-care centers nationwide, which a JAMA study published this past May found rates as high as 50 percent for acute respiratory infections in US emergency departments. Now the CDC has awarded UC Davis ED physician Larissa May a one-year grant to test two educational and behavioral interventions for physicians in emergency settings in California and Colorado. (2016-10-06)

Children's Hospital scientists identify possible target for prevention and treatment of pneumonia
Researchers at Children's Hospital of Pittsburgh of UPMC have identified a key protein target that may be a crucial factor in the development of a vaccine to prevent and new therapies to treat pneumonia, the leading killer of children worldwide. (2008-02-11)

Antibiotics can boost bacterial reproduction
The growth of bacteria can be stimulated by antibiotics, scientists at the University of Exeter have discovered. (2017-01-30)

Why antibiotics fail
UCSB biologists correct a flaw in the way bacterial susceptibility to these drugs is tested. (2017-06-01)

Four simple tests could help GPs spot pneumonia and reduce unnecessary antibiotics
Testing for fever, high pulse rate, crackly breath sounds, and low oxygen levels could be key to helping GPs distinguish pneumonia from less serious infections, according to a large study published in the European Respiratory Journal. (2017-11-22)

Antibiotics could be cut by up to one-third, say dairy farmers
Nine in 10 dairy farmers participating in a new survey from the Royal Association of British Dairy Farmers (RADBF) say that the farming industry must take a proactive lead in the battle against antibiotic resistance. Those questioned also think that over the next five years they could cut their own antibiotic use by almost one-third in dry cow therapy and one-fifth in clinical mastitis. (2016-10-06)

Botulinum-type toxins jump to a new kind of bacteria
A toxin much like the one that causes botulism has unexpectedly turned up in a completely different type of bacteria - Enterococcus. Where it came from is unclear, but the finding is concerning because enterococci have lately become a leading cause of multi-drug-resistant infections, especially in health care settings. (2018-01-26)

Scientists make it possible to rank the risk of resistance genes
A new study published in Nature Communications will help to predict antibiotic resistance evolution and thus guide future drug development. (2018-02-06)

Fungi have enormous potential for new antibiotics
Fungi are a potential goldmine for the production of pharmaceuticals. This is shown by researchers at Chalmers University of Technology, who have developed a method for finding new antibiotics from nature's own resources. The findings -- which could prove very useful in the battle against antibiotic resistance -- were recently published in the journal, Nature Microbiology. (2017-04-20)

Antibiotics promote resistance on experimental croplands
Canadian researchers have generated both novel and existing antibiotic resistance mechanisms on experimental farmland, by exposing the soil to specific antibiotics. The research is published in Applied and Environmental Microbiology, a journal of the American Society for Microbiology. (2017-06-16)

Study examines urinary tract infections and antibiotic use in nursing homes
In a Journal of the American Geriatrics Society study of nursing homes in the tropics, one in five residents had received antibiotics within the last 30 days. Also, urinary tract infection (UTI) accounted for 40 percent of all infections treated with antibiotics within the last 30 days. (2018-01-10)

Researchers downplay MRSA screening as effective infection control intervention
Three Virginia Commonwealth University epidemiologists are downplaying the value of mandatory universal nasal screening of patients for MRSA, arguing that proven, hospital-wide infection control practices can prevent more of the potentially fatal infections. (2008-10-23)

Antibiotics may be inappropriate for uncomplicated diverticulitis
Antibiotics are advised in most guidelines on diverticulitis, which arises when one or more small pouches in the digestive tract become inflamed or infected. Results from a randomized trial question the effectiveness of this practice, however. (2016-10-04)

Antibiotics legitimately available in over-counter throat medications could contribute to increased antibiotic resistance
New research presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Amsterdam, Netherlands (April 13-16) shows that the inappropriate of use of antibiotics legitimately available in over-the-counter (OTC) throat medications could be contributing to antibiotic resistance, thereby going against World Health Organization (WHO) goals. (2019-04-11)

Effect of stopping behavioral interventions on inappropriate antibiotic prescribing
In the 12 months after removing behavioral interventions, inappropriate antibiotic prescribing for acute respiratory infections increased relative to control practices, according to a study published by JAMA. (2017-10-10)

Antibacterial combination could fight drug-resistant tuberculosis
Pairing the antibiotic ceftazidime with the enzyme inhibitor avibactam may be an effective treatment for drug-resistant tuberculosis, a new study reports. This antibacterial drug combination -- already in clinical use for Gram-negative bacterial infections -- could aid in stemming the growing global drug-resistant tuberculosis crisis. (2017-08-30)

Antibiotic treatment targets difficult asthma
Hunter researchers have shown that a commonly available antibiotic can improve the quality of life of patients with difficult asthma, and may also generate significant health care savings. (2007-12-17)

Antibiotics still routinely prescribed in the ER for infants with viral lung infections
Despite recommendations first issued more than a decade ago, antibiotics are still routinely prescribed in US emergency rooms for infants with bronchiolitis, a common viral lung infection. Published in the Journal of the Pediatric Infectious Diseases Society, the findings highlight a concerning lag in translating evidence-based guidelines into clinical practice and underscore the need to continue educating health care providers and the public about appropriate antibiotic use. (2019-01-17)

Antibiotics can inhibit skin lymphoma
New research from the LEO Foundation Skin Immunology Research Center at the University of Copenhagen shows, surprisingly, that antibiotics inhibit cancer in the skin in patients with rare type of lymphoma. (2019-07-25)

Racial and ethnic differences seen in antibiotics prescribed for viral illnesses in pediatric EDs
Non-Latino white children seeking treatment for viral infections in the Emergency Department are about twice as likely to receive an antibiotic unnecessarily compared with non-Latino black children or Latino children, a multi-center study indicates. (2017-09-05)

New book on Antibiotics and Antibiotic Resistance from CSHLPress
'Antibiotics and Antibiotic Resistance' from CSHLPress examines the major classes of antibiotics, together with their modes of action and mechanisms of resistance. Well-established antibiotics (e.g., β-lactams) are covered, as are lesser-used drugs that have garnered recent interest (e.g., polymyxins) and new compounds in the development pipeline. Also examined is how bacteria evolve ways to resist disruptions by modifying the drug or drug target or by controlling access of the drug to the cell. (2016-08-17)

First proof a synthesized antibiotic is capable of treating superbugs
A 'game changing' new antibiotic which is capable of killing superbugs has been successfully synthesized and used to treat an infection for the first time -- and could lead to the first new class of antibiotic drug in 30 years. (2018-03-23)

Using rank order to identify complex genetic interactions
Applying new math, Kristina Crona, an American University assistant professor who researches in the area of mathematical biology, and her colleagues show how ranking pathogen mutants can help scientists understand how mutants evolve to resist drug treatments. This line of research could have implications for the treatment of diseases that can resist drug treatments, such as HIV and malaria. (2018-01-03)

Mefloquine effectively prevents malaria during pregnancy but is not well tolerated
The antimalarial drug mefloquine is more effective than the currently recommended treatment to prevent malaria infection in pregnant women living in endemic countries of sub-Saharan Africa, but the high frequency of adverse events represents a barrier to its use. These are the conclusions of a meta-analysis performed by ISGlobal -- a centre supported by the 'la Caixa' Foundation -- and published in the Cochrane Database of Systematic Reviews, a leading journal in systematic reviews on health issues. (2018-04-05)

Modified mushrooms may yield human drugs
Mushrooms might serve as biofactories for the production of various beneficial human drugs, according to plant pathologists who have inserted new genes into mushrooms. (2007-06-22)

Potential new way to limit antibiotic resistance spreading
One of the biggest current threats to global health is the rise of multi-drug resistant bacteria, caused by the spreading of antibiotic resistance amongst them. In an attempt to help fight this threat, EMBL researchers have unraveled the molecular basis of a major antibiotic resistance transfer mechanism. They also developed molecules and a proof-of-principle for blocking this transfer. Cell publishes their results on March 15. (2018-03-15)

To avoid a post-antibiotic world, researchers target animal farming and meat intake
A new study in Science by researchers at the Center for Disease Dynamics, Economics & Policy (CDDEP) and partners analyzes and describes a comprehensive strategy for preserving antibiotic effectiveness by reducing antibiotic use in farm animals up to 80 percent globally by the year 2030. The study was co-authored by researchers at the Princeton Environmental Institute, Princeton University (USA); Institute of Integrative Biology, ETH Zurich (Switzerland); the Université Libre de Bruxelles (Belgium); and the Food and Agriculture Organization of the United Nations (Italy). (2017-09-28)

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