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Popular Arthritis News and Current Events, Arthritis News Articles.
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Novel PET imaging method more fully evaluates extent of rheumatoid arthritis inflammation
A new positron emission tomography (PET) imaging method more fully evaluates the extent of rheumatoid arthritis by targeting translocator protein (TSPO) expression in the synovium (joint lining tissue). The study is featured in the July issue of The Journal of Nuclear Medicine. (2018-07-09)

Blocking one receptor could halt rheumatoid arthritis
Researchers at the University of Illinois at Chicago College of Medicine have shown for the first time how the activation of a receptor provokes the inflammation and bone degradation of rheumatoid arthritis -- and that activation of this one receptor, found on cells in the fluid of arthritic joints, is all that is required. (2014-09-10)

Cellular stress increases the probability of developing autoimmune diseases
Researchers found that cellular stress enhances the activation of certain type of immune cells with implications in many chronic inflammatory conditions. (2017-06-13)

Trial reveals differences in pain-relieving drugs when combined with aspirin
A landmark 2016 Cleveland Clinic study of widely used pain-relieving drugs showed that celecoxib (Celebrex) was associated with comparable cardiovascular safety and better gastrointestinal (GI) and kidney safety when compared with either naproxen (Naprosyn) and ibuprofen (Motrin). A new substudy analyzed outcomes in PRECISION based on the presence or absence of aspirin use with specific NSAIDs (nonsteroidal anti-inflammatory drugs). (2018-04-16)

Obesity may influence rheumatoid arthritis blood tests
New research reveals that in women, obesity may influence blood tests used to diagnose and monitor rheumatoid arthritis. The findings, which appear in Arthritis Care & Research, indicate that physicians need to take obesity into account when using these tests. (2017-04-10)

Researchers discover the unexpected role of platelets in immune response
Platelets play a much bigger role in our immune system than previously thought, according to Université Laval researchers. In addition to their role in coagulation and healing, platelets also act as the immune system's first responders when a virus, bacterium, or allergen enters the bloodstream. This discovery opens the door to new ways to treat patients with septic shock caused by viral or bacterial infection and people with auto-immune diseases like rheumatoid arthritis and lupus. (2018-02-01)

Heavy birthweight increases risk of developing rheumatoid arthritis
People who have a birthweight over 10 pounds are twice as likely to develop rheumatoid arthritis when they are adults compared to individuals born with an average birthweight, according to a study published by researchers from Hospital for Special Surgery online in advance of print in the Annals of the Rheumatic Diseases. While the mechanism for this association is unclear, the study identifies a potentially modifiable risk factor and highlights a potential way to decrease the incidence of the disease. (2008-06-30)

Researchers uncover link between immune function and osteoarthritic pain and progression
The study, published in the medical journal Osteoarthritis and Cartilage, found that monocytes, the white blood cells necessary to regulate immune responses, were more activated and pro-inflammatory in women with osteoarthritis, and that elevated inflammation and body mass index were associated with this increased activation. (2017-11-27)

Effort seeks to increase the number of trained rheumatology nurse practitioners and physician assistants
Due to an aging population and increasing prevalence of rheumatic disease, there are growing demands on clinicians who specialize in rheumatology. (2018-04-19)

Therapeutic drug monitoring does not improve remission for patients starting infliximab
New research presented at ACR Convergence, the American College Rheumatology's annual meeting, showed that patients with rheumatic diseases whose infliximab treatment was individually assessed and adjusted with a new strategy called therapeutic drug monitoring did not achieve remission at higher rates compared to those who received standard care. (2020-11-06)

New juvenile idiopathic arthritis guideline emphasizes disease-modifying treatments
The American College of Rheumatology (ACR) will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Convergence, the ACR's annual meeting. (2020-11-06)

Psoriasis onset determines if psoriatic arthritis patients develop arthritis or psoriasis first
In a new study presented at the 2019 ACR/ARP Annual Meeting, researchers found the age of psoriasis onset determines whether arthritis or psoriasis starts first in people with psoriatic arthritis. Additionally, they found that pustular psoriasis is associated with arthritis onset two years earlier than the intercept interval; and there is an increased delay for nail involvement, plaque psoriasis or family history of psoriasis from psoriasis to arthritis by approximately two years for each characteristic. (2019-11-09)

Experts seek to standardize treatments for childhood rheumatic diseases
Pediatric rheumatic diseases are a varied group of rare diseases including juvenile forms of arthritis, lupus, fibromyalgia, and other conditions. Currently, there is considerable variability in how patients with these diseases are treated in clinical practice, making it difficult to understand which therapies work best. (2018-01-15)

Serotonin deficiency implicated in rheumatoid arthritis
For the first time, serotonin (5-hydroxytryptamine, 5-HT) has been directly implicated in the pathophysiology of rheumatoid arthritis (RA). A report in The American Journal of Pathology shows that experimentally-induced RA in serotonin-deficient mice is worse than disease reported in controls and that some effects of RA can be reduced by serotonin or its agonists (compounds that activate serotonin receptors). (2016-03-09)

Screening could catch a quarter of hip fractures before they happen
Screening for osteoporosis could catch a quarter of hip fractures before they happen. A new study in The Lancet reveals that a simple questionnaire, combined with bone mineral density measurements for some, would help identify those at risk of hip fracture. The research, which involved more than 12,000 older women, found that screening through GP practices allowed patients to be targeted for treatment -- leading to a 28 percent reduction in hip fractures over five years. (2017-12-15)

Causes of death in rheumatoid arthritis patients
Mortality rates were increased for patients with rheumatoid arthritis relative to the general population across all causes of death in a recent Arthritis Care & Research analysis. (2018-03-07)

Rates of depression and anxiety may correlate with disease activity in early RA
The results of a study to be presented at the Annual European Congress of Rheumatology (EULAR 2018) suggest that rates of anxiety and depression in patients with rheumatoid arthritis correlate with measures of disease activity over the first year following diagnosis. (2018-06-15)

Noninvasive ultrasound stimulation of spleen could lead to new treatments for inflammatory arthritis
Researchers at the University of Minnesota, in collaboration with researchers at Medtronic, have shown that noninvasive daily ultrasound stimulation of the spleen in mice with inflammatory arthritis resulted in significantly less joint swelling compared to arthritic mice that were not treated. The research is a first step to developing new treatment options for more than a million people in the United States who currently suffer from rheumatoid arthritis. (2019-03-14)

Rheumatoid arthritis during pregnancy may increase chronic disease risk in children
New research reveals that children born to women with rheumatoid arthritis face an increased susceptibility for certain chronic diseases. (2017-12-11)

Bone marrow edema in lower spine is common in young athletes
New research indicates that young recreational and elite athletes commonly accumulate excess fluid in the bone marrow around the joint that connects the spine with the pelvis. (2018-03-13)

Researchers uncover higher prevalence of periodontal disease in rheumatoid arthritis patients
A recent study published in the June issue of the Journal of Periodontology, the official publication of the American Academy of Periodontology, uncovered yet another potential side effect of RA. Researchers in Berlin, Germany discovered that patients with RA have a higher incidence of periodontal disease compared to healthy controls. (2008-06-10)

Complex inhalers prevent patients from taking medicine
Respiratory disease patients with arthritis could struggle to manage their conditions because their inhalers are too fiddly for them to use, University of Bath research has found. (2018-02-23)

Disease burden in osteoarthritis is similar to rheumatoid arthritis
Osteoarthritis (OA) has traditionally been viewed as a highly prevalent but milder condition when compared with rheumatoid arthritis (RA), and some may believe that it is part of a normal aging process requiring acceptance, not treatment. A new study in Arthritis & Rheumatology indicates that OA and RA have similar impacts or burdens on patients when they first visit rheumatologists, however. (2019-03-20)

Bone marrow lesions can help predict rapidly progressing joint disease
A new study from the Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, shows lesions, which can best be seen on MRI scans, could help identify individuals who are more likely to suffer from more rapidly progressing osteoarthritis. (2016-01-15)

Methotrexate drug holiday improves flu vaccine efficacy in rheumatoid arthritis patients
People with RA who stop taking methotrexate treatment for just two weeks after they have a seasonal flu shot can improve the vaccine's efficacy without increasing RA disease activity, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego. (2017-11-04)

Biosimilar drugs could cut US health spending by $54 billion over next decade
Biosimilar drugs have been touted as one strategy to help curb the runaway costs of biologics that have advanced the treatment of illness such as rheumatoid arthritis and many cancers. A new study finds biosimilars could cut health care spending in the United States by $54 billion over the next decade. The savings are about 20 percent larger than a similar, widely cited analysis done three years ago by the same researchers. (2017-10-23)

Lupus may contribute to pregnancy-related complications
A new study found that lupus during pregnancy may have negative health impacts for women and their babies. (2016-02-01)

Phase 3 data show golimumab improved psoriatic arthritis symptoms
Patients with active psoriatic arthritis receiving monthly subcutaneous injections of golimumab experienced significant and sustained improvements in the joint and skin manifestations of the disease, according to findings from the largest phase 3 biologic study ever completed in subjects with psoriatic arthritis. (2007-11-07)

Osteoarthritis just as severe as rheumatoid arthritis
Rheumatologists more likely to underestimate clinical status of their OA patients than their RA patients (2016-06-09)

Groundbreaking gene therapy trial set to cure hemophilia
A 'cure' for hemophilia is one step closer, following results of a groundbreaking gene therapy trial led by Queen Mary University of London and the NHS in London. (2017-12-14)

New study reveals hidden burden of Lupus among Hispanic and Asian women in Manhattan
Within Manhattan's diverse population, the autoimmune disease lupus affects Hispanic and Asian women more frequently than white women, according to a new study led by investigators at NYU School of Medicine. The findings also show that these female ethnic populations are more adversely affected by lupus and have significantly greater organ complications - namely kidney disease. Overall, the investigators found substantial disparities in prevalence and manifestations of lupus by race/ethnicity among borough residents. (2017-09-11)

Scientists identify new marker of arthritis in mice
Researchers have discovered a new marker of arthritis in mice that can be used noninvasively to both identify joints with established arthritis and to predict subsequent joint swelling. (2017-11-22)

Discovery of novel biomarker with remarkable specificity to rheumatoid arthritis
University of Tsukuba-centered researchers identified the protein citrullinated ITIH4 as a new biomarker with high specificity in patients with rheumatoid arthritis (RA). Notably, citrullinated ITIH4 levels were specifically increased in sera of patients with RA and significantly correlated with disease activity. Citrullinated ITIH4 might be a novel biomarker to distinguish RA from other rheumatic diseases and for assessing disease activity in patients with RA. (2018-05-10)

Contraceptive pill linked to lowered risk of rheumatoid arthritis
Taking the contraceptive pill, particularly for seven or more consecutive years, is linked to a lowered risk of developing rheumatoid arthritis, finds research published online in the Annals of the Rheumatic Diseases. (2017-08-17)

Gum disease may be a key initiator of rheumatoid arthritis related autoimmunity
The results of a study presented at the Annual European Congress of Rheumatology (EULAR 2018) demonstrates increased levels of gum disease, and disease-causing bacteria, in individuals at risk of rheumatoid arthritis (RA). (2018-06-15)

The toxic sugar tree: Mapping the evolutionary history of a cancerous sugar gene
The gene CMAH, that allows for the synthesis of a sugar called Neu5Gc, is missing from humans. This sugar is present in red meats, some fish and dairy products. When humans consume an animal with that gene, the body has an immune reaction to the foreign sugar, which can cause inflammation, arthritis, and cancer. University of Nevada, Reno researchers, have analyzed 322 animal genome sequences looking for animals with the presence of active CMAH genes. (2017-12-13)

Different outcomes by race/ethnicity among patients with COVID-19 and rheumatic disease
Among US patients with rheumatic disease and COVID-19, racial/ethnic minorities had higher risks of needing to be hospitalized and put on ventilators. The findings come from an analysis published in Arthritis & Rheumatology. (2020-11-04)

Hand osteoarthritis is a common condition
A new study estimates that the lifetime risk of symptomatic hand osteoarthritis is 40 percent, and nearly one in two women and one in four men will develop the condition, which affects hand strength and function and causes disability in activities of daily living. (2017-05-04)

Study links Celebrex, heart valve calcification after earlier research declared drug safe
On National Heart Valve Disease Awareness Day, Vanderbilt study disputes that Celebrex has no more impact on valves than older drugs in its class. (2019-02-22)

Study finds bacteria in milk linked to rheumatoid arthritis
A strain of bacteria commonly found in milk and beef may be a trigger for developing rheumatoid arthritis in people who are genetically at risk, according to a new study from the University of Central Florida. (2018-01-30)

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