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Defect in non-coding DNA might trigger brain disorders such as severe language impairment
Genetic variation in the non-coding DNA could give rise to language impairments in children and other neurodevelopmental disorders including schizophrenia, autism, and bipolar disorder, scientists from the Max Planck Institute for Psycholinguistics and Radboud University in Nijmegen found. Molecular Psychiatry publishes their work based on a new approach on March 14. (2017-03-14)

New test for mysterious metabolic diseases developed at Stanford/Packard
Scientists at Stanford University School of Medicine have devised a much-needed way to monitor and find treatments for a mysterious and devastating group of metabolic diseases that arise from mutations in cells' fuel-burning mechanism. (2009-02-10)

Gene regulators work together for oversized impact on schizophrenia risk
Researchers have discovered that gene expression regulators work together to raise an individual's risk of developing schizophrenia. Such synergistic interactions seen with schizophrenia-like gene expression changes in modeled induced human neurons matched changes found in patients' brains. (2019-09-23)

STAT3 identified as important factor in emotional reactivity
In a study published in leading journal ''Molecular Psychiatry'', MedUni Vienna researchers led by Daniela Pollak from the Division of Neurophysiology and Neuropharmacology showed that STAT3 plays an important role in the serotonergic system as a molecular mediator for controlling emotional reactivity, thereby establishing a mechanistic link between the immune system, serotonergic transmission and affective disorders such as depression. (2020-10-14)

New genes related to autism spectrum disorder
The lack of some genes in the BEC/TCEAL cluster could be related to some alterations associated with the autism spectrum disorder, according to a preclinical study published in the journal Genome Biology, and led by Professor Jordi Garcia Fernàndez, from the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona (IBUB), and researcher Jaime Carvajal, from the Andalusian Centre for Developmental Biology - University Pablo de Olavide (CSIC-UPO). (2020-10-26)

MIT model helps researchers 'see' brain development
Large mammals -- humans, monkeys and even cats -- have brains with a somewhat mysterious feature: the outermost layer has a folded surface. Understanding the functional significance of these folds is one of the big open questions in neuroscience. Now a team led by MIT, Massachusetts General Hospital and Harvard Medical School researchers has developed a tool that could aid such studies by helping researchers (2007-04-09)

Secrets of the human brain unlocked
Human intelligence is being defined and measured for the first time ever, by researchers at the University of Warwick. The research could lead to developments in artificial intelligence, and better treatment of mental health disorders. (2016-07-18)

Embracing the 5G era
To meet the demands of 2020, the 5G research has attracted global attention and made remarkable progress. Now, researchers in China have overviewed the latest research progress on 5G systems and discussed its potential architecture and several promising key techniques. The research result has been published on SCIENCE CHINA Information Sciences no. 4 2015. (2015-04-28)

Bipolar disorder -- an understudied condition
Despite a prevalence of about five percent in the community and 50 percent in depressed outpatients, the treatment of bipolar II disorder and related disorders is understudied. Recent advances in this area, which have mainly been related to these conditions, are discussed in a Seminar in this week's issue of The Lancet. (2007-03-15)

Autistic children recognize stereotypes based on race and sex
Children with autism, who are unable to grasp the mental states of others, can nonetheless identify with conventional stereotypes based on a person's race and sex, researchers report in the June 19 issue of Current Biology, published by Cell Press. (2007-06-18)

Computer modeling provides insight into cellular-level effects of schizophrenia risk genes
Numerous genetic variants associated with risk for schizophrenia have been identified. However, little is known about how these genes have their effects in the brain. (2016-01-21)

Signs of the ancient mariner: Scientists locate elements implicated in human genetic disorders
In a study published in the September issue of Genome Research, scientists use fluorescent imaging to locate genetic elements called mariner transposons on the human genome. Their work reveals potential links between these elements and a number of hereditary human diseases. (1999-09-27)

Lending late neurons a helping hand
Researchers at UNIGE have discovered that even a slight delay of the neuronal migration may lead to behavioural disorders that are similar to autistic characteristics in human. Furthermore, they found that these disorders are due to the abnormally low activity of the late neurons, which leads to permanent deficit of interneuronal connections. They succeeded in correcting the activity of the relevant neurons, thereby restoring the missing connections and preventing the appearance of behavioural disorders. (2017-11-07)

Friend or foe? How the unconscious mind picks out faces in a crowd
Imagine you're walking down a busy street like Times Square in New York. There are tons of people around. As you make your way through the crowd, your brain notices several faces but ignores the rest. Why is that? What are the processes that determine which faces our brain 'chooses' to see and those it allows to fade into the background? Researchers observed that the facial dimensions that were most quickly registered by participants were ones that indicated power and dominance. (2017-12-19)

As brain extracts meaning from vision, study tracks progression of processing
Study finds that six brain regions shared more responsibility than thought for how the brain moves from raw perception to determining the categorical meaning of what's seen. (2018-07-10)

Stanford scientists tie specific brain circuit to sociability in mice
Social behavior in mouse models of autism spectrum disorder normalized when investigators triggered the release of a specific signaling substance, serotonin, in a single part of the animals' brains, according to a study from the Stanford University School of Medicine. (2018-08-08)

In kids with autism, short questionnaire may detect GI disorders
Though they can be difficult to detect, gastrointestinal disorders are common in kids with autism, sometimes causing anger, aggression, and other behavior problems. (2018-10-22)

Friend or foe? Brain area that controls social memory also triggers aggression
Columbia scientists have identified a brain region that helps tell an animal when to attack an intruder and when to accept it into its home. (2018-12-05)

Study finds no increased risk of autism, ADHD with prenatal antidepressant exposure
An analysis of medical records data from three Massachusetts health care systems finds no evidence that prenatal exposure to antidepressants increases the risk for autism and related disorders or for attention-deficit hyperactivity disorder. (2016-01-05)

Virginia Tech's De Vita receives government's highest of engineering honors to study pelvic disorder
Virginia Tech engineering faculty member Raffaella De Vita's work on pelvic floor disorders could potentially transform surgical reconstruction methods and post-operative rehabilitation procedures for females suffering from problems with supporting structures of the uterus and the vagina. (2014-01-06)

New model for autism suggests women carry the disorder and explains age as a risk factor
A new model for understanding how autism is acquired has been developed by a team of researchers led by Cold Spring Harbor Laboratory and Albert Einstein College of Medicine. The researchers analyzed data on autism incidence and found a previously unrecognized pattern. The pattern can be explained by assuming that spontaneous germ-line mutation is a significant cause of the disorder. (2007-07-24)

Cell discovery could hold key to causes of inherited diseases
Fresh insights into the protective seal that surrounds the DNA of our cells could help develop treatments inherited muscle, brain, bone and skin disorders. (2013-02-26)

Penn researcher calls on the scientific community to defend individuals with disabilities
The potential repeal of the Affordable Care Act (ACA) threatens to eliminate critical mental and behavioral health services for people living with autism and other disabilities. (2017-03-09)

Autism finding could lead to simple urine test for the condition
Children with autism have a different chemical fingerprint in their urine than non-autistic children, according to new research published tomorrow in the print edition of the Journal of Proteome Research. The researchers behind the study, from Imperial College London and the University of South Australia, suggest that their findings could ultimately lead to a simple urine test to determine whether or not a young child has autism. (2010-06-03)

Sleep changes seen with fetal alcohol exposure partly explain learning and mood problems
Slow-wave sleep -- the deeper sleep during which the brain turns each day's events into permanent memories -- is fragmented in adulthood in people exposed to high levels of alcohol in the womb. This is according to a study conducted by researchers at NYU Langone Medical Center and its Nathan S. Kline Institute for Psychiatric Research, and recently published online in the journal Neuroscience. (2016-02-24)

Inattentive kids show worse grades in later life
Researchers found that inattentiveness in childhood was linked to worse academic performance up to 10 years later in children with and without ADHD, even when they accounted for the children's intellectual ability. The results highlight the long-term effects that childhood inattention can have on academic performance, and suggest that parents and teachers should address inattentiveness in childhood. (2017-08-29)

Contagious yawning more closely associated with perceptual sensitivity than empathy
A new study out of Tohoku University suggests that contrary to common belief that the yawning contagion is associated with empathy, it is in fact, more likely that perceptual sensitivity is to blame. (2017-09-05)

Age matters: Paternal age and the risk of neurodevelopmental disorders in children
It is no secret that genetic factors play a role in determining whether children have neurodevelopmental disorders. Maternal exposure to drugs and viral or bacterial illnesses can be detrimental too. (2020-04-20)

Simple test could improve public attitudes to autism
Psychologists from Bath and Essex suggest existing ways of testing public attitudes towards autism are not fit for purpose. (2020-08-21)

Experts urge BMI method for calculating weight in kids with eating disorders
In a study to be published online Jan. 4, 2012, in the journal Pediatrics, researchers from the University of Chicago, the Harvard School of Public Health and the University of Rochester Medical Center compared three common methods for calculating expected body weight of adolescents with eating disorders and found that the body mass index percentile method is recommended for clinical and research purposes. (2012-01-04)

Women with mental disorders less likely to have mammograms
Women with mental disorders are less likely to have screening mammograms than women without mental illness, although the nature of the mental illness does play a role. Prior to this study, little was known about whether the type or severity of mental illness influences receipt of preventive services such as mammograms. (2006-10-26)

Evaluation between maternal mental health and discharge readiness
New research indicates that mothers with a history of mental health disorders feel less ready for discharge from the NICU than with mothers without a mental health history. (2017-03-28)

The answer is blowing in the wind
Physics research provides new insights into the fluctuations of wind energy, with implications for engineering and policy. (2016-12-30)

A way to predict whether children with DiGeorge syndrome will develop autism or psychosis
New findings by researchers at UCLA and the University of Pittsburgh are the first to suggest a potential way to predict whether children with DiGeorge syndrome will develop one of two mental impairments. In a study published in PLOS ONE, the researchers report having isolated specific genetic differences between people with the syndrome who have autism and those who have psychosis. (2015-07-24)

How does the brain make perceptual predictions over time?
NYU neuroscientist David Heeger offers a new framework to explain how the brain makes predictions. He outlines how 'prediction' may be a general principle of cortical function -- along with the already-established role of inference. (2017-02-06)

Psychiatric disorders do not increase risk of Alzheimer's disease
Psychiatric disorders do not increase the risk of Alzheimer's disease, according to a recent study from the University of Eastern Finland. However, the prevalence of psychiatric diagnoses increased before the Alzheimer's diagnosis, which might be due to prodromal symptoms of Alzheimer's disease. The results were published in European Psychiatry. (2017-04-04)

High quality early intervention for children with autism quickly results in costs savings
A recent study by Penn Medicine researchers published online ahead of print in the Journal of the American Academy of Child & Adolescent Psychiatry found that the costs associated with the Early Start Denver Model (ESDM), one evidence-based treatment for young children with autism, were fully offset after only two years following intervention due to reductions in children's use of other services. (2017-08-08)

Real or crocodile tears? Psychopaths may not know the difference
New research has found people with high levels of psychopathic traits have difficulty telling when someone is genuinely afraid or upset, based on people's facial expressions. (2018-08-01)

Structural fluctuation evaluation in substances from measurement data
Microstructure analysis of materials is a key technology for new material research. Using an information extraction technique called sparse modeling, a collaboration of Japanese researchers has developed the world's first method of analyzing a material's atomic structure using only measured data. This method needs no prior assumptions of atomic structure, which are required in conventional microstructure analysis methods. This new approach is expected to improve the functionality of and give longer life to batteries. (2018-08-21)

Growing up in poverty increases diagnoses of psychosis-spectrum mental illnesses
Growing up in impoverished urban neighborhoods more than doubles your chances over the average person of developing a psychosis-spectrum disorder by the time you reach middle adulthood, according to a new UC Davis and Concordia University study of nearly 4,000 families who were monitored over 30 years. (2019-04-24)

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