Popular Bleeding News and Current Events

Popular Bleeding News and Current Events, Bleeding News Articles.
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Novel heart pump shows superior outcomes in advanced heart failure
Severely ill patients with advanced heart failure who received a novel heart pump -- the HeartMate 3 left ventricular assist device (LVAD) -- suffered significantly fewer strokes, pump-related blood clots and bleeding episodes after two years, compared with similar patients who received an older, more established pump, according to research presented at the American College of Cardiology's 68th Annual Scientific Session. (2019-03-18)

The future of sutures and staples: A sealant inspired by slugs
A new Clinical Implications of Basic Research paper highlights a novel surgical adhesive on the horizon. (2017-11-22)

Stress and diet associated with brain bleeds in sub-Saharan Africa
Stress may double the risk of brain bleeds related to high blood pressure, while consuming green leafy vegetables is strongly protective, according to the largest study of stroke in sub-Saharan Africa, presented at the American Stroke Association's International Stroke Conference 2018, a world premier meeting dedicated to the science and treatment of cerebrovascular disease for researchers and clinicians. (2018-01-26)

Bleeding stroke associated with onset of dementia
Bleeding within the brain, or intracerebral hemorrhage, was associated with a high risk of developing dementia post stroke, according to research presented at the American Stroke Association's International Stroke Conference 2016. (2016-02-17)

Bevacizumab dramatically improves severe hereditary hemorrhagic telangiectasia (HHT) associated bleeding
Patients with hereditary hemorrhagic telangiectasia (HHT) with severe bleeding, who were treated with intravenous bevacizumab, reported a marked reduction in nose bleeds and gastrointestinal bleeding and were able to stop or considerably reduce blood transfusions, resulting in significantly improved quality of life. A new study published in Mayo Clinic Proceedings provides good quality evidence for the excellent safety profile and efficacy of intravenous bevacizumab in the management of these patients. (2018-01-29)

Heart attack risk increases with six-month dual antiplatelet therapy
The combined rate of death from any cause, heart attack or stroke within 18 months was not significantly different in patients with acute coronary syndrome (ACS) who were randomly assigned to receive dual antiplatelet therapy (DAPT) for either six months or at least 12 months after receiving a drug-eluting stent. (2018-03-12)

Daily low-dose aspirin found to have no effect on healthy life span in older people
In a clinical trial to determine the effects of daily low-dose aspirin in healthy older adults without previous cardiovascular events, aspirin did not prolong healthy, independent living free of dementia or physical disability. These findings from the ASPirin in Reducing Events in the Elderly (ASPREE) trial, partially supported by the National Institutes of Health, were published online on September 16, 2018 in three papers in The New England Journal of Medicine. (2018-09-16)

Safety of bioabsorbable polymer against durable polymer DES in high-risk PCI patients
A novel study sought to reveal whether drug-eluting stents (DES) coated with bioabsorbable polymer (BP) presented a safety advantage without compromising efficacy compared to durable polymer (DP) formulations. Subgroup findings from the TWILIGHT trial were presented today during the SCAI 2020 Scientific Sessions Virtual Conference. (2020-05-14)

Dengue fever linked to increased risk of stroke
A new study has found that people with dengue fever have a higher risk of stroke, especially in the first 2 months following infection. The study is published in CMAJ (Canadian Medical Association Journal). (2018-03-12)

Drug reduces inflammation in stroke patients
An anti-inflammatory drug given to patients in the early stages of a stroke has been shown by researchers at The University of Manchester and Salford Royal NHS Foundation Trust to reduce harmful inflammation. The drug, Kineret©, licenced for treating rheumatoid arthritis, was given as a small injection just under the skin without giving the patients any identifiable adverse reactions. (2018-03-26)

Rethinking dual antiplatelet guidelines in acute coronary syndrome? (CHANGE-DAPT)
New research presented at ESC Congress today1 suggests that for acute coronary syndrome (ACS) patients who require percutaneous coronary intervention (PCI), treatment according to contemporary guidelines for dual anti-platelet therapy (DAPT) could be less preferable than sticking to older guidelines. (2017-08-29)

High doses of ibuprofen cause significant GI bleeding, despite safety profile
People who take high doses of ibuprofen on a regular basis are three times more likely to experience gastrointestinal (GI) bleeding than those who do not take painkillers. Results of a small, retrospective analysis published today in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology show that significant GI bleeding can be observed as early as three days after starting an ibuprofen regimen in otherwise healthy people. (2005-11-01)

A strange case of upper obstructive syndrome
Aorto-duodenal fistulae constitute 80 percent of aorto-enteric fistulae, presenting with upper gastrointestinal bleeding. Rarely do they present with a history of persistent occlusive syndrome: This is the case of a 59-year-old man who underwent an aortic-bi-femoral bypass five years ago, presenting with dyspepsia and biliary vomiting. (2008-02-22)

Use of non-vitamin K blood-thinners with certain medications associated with increased risk of major bleeding
Among patients with nonvalvular atrial fibrillation, concurrent use of certain commonly prescribed medications with non-vitamin K oral anticoagulants was associated with an increased risk of major bleeding, according to a study published by JAMA. (2017-10-03)

Study identifies double-balloon enteroscopy as cost-effective approach for obscure GI bleeding
A cost-effectiveness analysis conducted by researchers at Stanford University Hospital in Calif., shows that an initial double-balloon enteroscopy is a cost-effective approach for patients with obscure gastrointestinal bleeding. However, capsule-directed DBE, which is when the findings from an initial small bowel capsule endoscopy exam are used to guide the DBE procedure, may be preferred as the initial test due to the potential for fewer complications and decreased utilization of endoscopic resources. (2008-11-24)

Therapy derived from parasitic worms downregulates proinflammatory pathways
A therapy derived from the eggs of parasitic worms helps to protect against one of chemotherapy's debilitating side effects by significantly downregulating major proinflammatory pathways, reducing inflammation. (2019-02-07)

Imaging stroke risk in 4-D
A new MRI technique developed at Northwestern University detects blood flow velocity to identify who is most at risk for stroke, so they can be treated accordingly. (2016-10-07)

Blood thinner significantly reduces the risk of death after non-cardiac surgery
The study enrolled 1,754 patients in 19 countries, 51 percent of whom were male, with an average age of 70 years. After an average follow-up of 16 months, 11 percent of patients treated with dabigatran experienced a MINS-related event, compared with 15 percent of patients who received a placebo. This translates to a 28 percent reduction in risk for patients receiving dabigatran. (2018-03-12)

Researchers develop injectable bandage
A penetrating injury from shrapnel is a serious obstacle in overcoming battlefield wounds that can ultimately lead to death.Given the high mortality rates due to hemorrhaging, there is an unmet need to quickly self-administer materials that prevent fatality due to excessive blood loss. (2018-04-02)

Which pain medication is safest for arthritis patients?
In a recent Alimentary Pharmacology & Therapeutics study, arthritis patients taking nonsteroidal anti-inflammatory drugs (NSAIDs) for pain plus a stomach acid-reducing medicine called esomeprazole had infrequent gastrointestinal side effects. (2018-04-19)

First results announced for the AVIATOR 2 international multicenter registry
Results of the AVIATOR 2 international registry are being presented as late-breaking clinical science at the Society for Cardiovascular Angiography and Interventions (SCAI) 2018 Scientific Sessions. (2018-04-27)

Lack of standard dosage for blood thinners can lead to bleeding during bariatric surgery
Rutgers researchers have found a way to reduce bleeding in patients following bariatric surgery. (2019-01-09)

Review finds more effective drugs to stop bleeding after childbirth
New evidence from a Cochrane review suggests that alternative drugs may be more effective than the standard drug currently used to stop women bleeding after childbirth. (2018-04-26)

UMBC researchers develop nanoparticles to reduce internal bleeding caused by blast trauma
Currently, there are no treatments available to address internal bleeding in the field but early intervention is key or survival and better outcomes. UMBC researchers and collaborators investigated the role of nanoparticles they developed to stop internal bleeding on the damage inflicted by blast trauma. (2018-07-13)

Aspirin, acid blocker a-day keeps GI bleeding
In a new study, University of Michigan researchers reveal that over-the-counter acid-blockers are worth the price for coronary heart disease patients taking low-dose aspirin as a preventative measure. (2008-08-11)

When two is better than three: Dual antithrombotic therapy cuts bleeding risk
Clinical trial finds that dabigatran dual therapy after stenting reduced bleeding risk for patients with atrial fibrillation compared with standard triple therapy. (2017-08-27)

New study: Pine bark significantly reduces endometriosis
A new study to be published in an upcoming edition of the Journal of Reproductive Medicine reveals that Pycnogenol, an antioxidant plant extract from the bark of the French maritime pine tree, significantly reduces symptoms of endometriosis by 33 percent. (2007-03-07)

Researchers find combination therapy works best for heart diseases
A major international study has found that the combination of two drugs -- rivaroxaban and aspirin -- is superior to aspirin alone in preventing further heart complications in people with vascular disease. The study of 27,400 people with stable coronary or peripheral artery disease from 33 countries worldwide shows that the combination of 2.5 mg of rivaroxaban twice daily plus 100 mg of aspirin once daily was significantly better than only aspirin or only rivaroxaban in preventing heart attacks, strokes and death. (2017-08-27)

More than one day of early-pregnancy bleeding linked to lower birthweight
Women who experience vaginal bleeding for more than one day during the first trimester of pregnancy may be more likely to have a smaller baby, compared to women who do not experience bleeding in the first trimester, suggest researchers at the National Institutes of Health. (2018-05-09)

New method to assess platelet health could help ER doctors
UW researchers have created a novel system that can measure platelet function within two minutes and can help doctors determine which trauma patients might need a blood transfusion upon being admitted to a hospital. (2019-03-13)

A new breakthrough in timing of urgent endoscopy for gastrointestinal bleeding patients
Endoscopy plays a major role in the diagnosis and therapy of upper gastrointestinal bleeding. An endoscopic group in Italy investigated whether a simple clinical score prior to endoscopy was efficient in selecting those patients. Their study showed that such an endoscopic triage is strongly associated with the detection of endoscopic signs of recent hemorrhage. (2008-09-10)

Stopping DAPT after one-month improved outcomes in stent patients
Patients who stopped taking aspirin one month after receiving a stent in the heart's arteries but continued taking the P2Y12 inhibitor clopidogrel fared significantly better after one year compared with those who followed the standard practice of continuing both medications, according to research presented at the American College of Cardiology's 68th Annual Scientific Session. (2019-03-18)

Groundbreaking gene therapy trial set to cure hemophilia
A 'cure' for hemophilia is one step closer, following results of a groundbreaking gene therapy trial led by Queen Mary University of London and the NHS in London. (2017-12-14)

Video of blood clot contraction reveals how platelets naturally form unobtrusive clots
The first view of the physical mechanism of how a blood clot contracts at the level of individual platelets is giving researchers a new look at a natural process that is part of blood clotting. The team describes how specialized proteins in platelets cause clots to shrink in size. (2017-11-08)

How serious is postmenopausal bleeding?
If you're postmenopausal, you shouldn't be bleeding. The very definition of menopause is having gone more than 12 months without a period. So if you're still bleeding, something is wrong. Determining the seriousness of the problem and treating it, is not always evident. A presentation at The North American Menopause Society (NAMS) Annual Meeting in Philadelphia Oct. 11-14, provides new evidence about the reliability and risks of various diagnostic approaches. (2017-10-11)

Children with asymptomatic brain bleeds as newborns show normal brain development at age 2
A study by UNC researchers finds that neurodevelopmental scores and gray matter volumes at age two years did not differ between children who had MRI-confirmed asymptomatic subdural hemorrhages when they were neonates, compared to children with no history of subdural hemorrhage. (2020-10-30)

Infertility treatment affects oral health
Researchers found that women undergoing ovulation induction for infertility treatment for more than three menstrual cycles experience higher gingival inflammation, bleeding and gingival crevicular fluid (GCF). This study appeared in the recent issue of the Journal of Periodontology. (2004-06-22)

Experimental antiplatelet compound for acute stroke shows promise
An experimental compound inhibited clot formation without increased bleeding, a common side effect of current anticlotting therapies, in a phase I study. First-in-human study shows the anticlotting drug was well-tolerated without serious safety concerns in healthy volunteers. Next-phases will gauge effectiveness and safety in patients with acute ischemic strokes. (2019-04-18)

Plotting the downward trend in traditional hysterectomy
Fewer women are getting hysterectomies in every state across the country. (2018-01-23)

Elagolix reduces menstrual bleeding from most common uterine tumors
A new oral drug significantly reduced menstrual bleeding for women with the most common gynecologic tumors in the United States - benign tumors that disproportionately affect African-Americans, an international clinical trial found. (2018-11-09)

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