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Popular Bleeding News and Current Events, Bleeding News Articles.
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Elagolix reduces menstrual bleeding from most common uterine tumors
A new oral drug significantly reduced menstrual bleeding for women with the most common gynecologic tumors in the United States - benign tumors that disproportionately affect African-Americans, an international clinical trial found. (2018-11-09)

Video of blood clot contraction reveals how platelets naturally form unobtrusive clots
The first view of the physical mechanism of how a blood clot contracts at the level of individual platelets is giving researchers a new look at a natural process that is part of blood clotting. The team describes how specialized proteins in platelets cause clots to shrink in size. (2017-11-08)

UB Oral Biologists Find Link Between Gum Disease And Passive Exposure To Tobacco Smoke
Passive smoking, implicated in middle-ear infections and asthma in children, also may be a major cause of periodontal disease in adult non-smokers, the first study to look at this relationship has shown. Research conducted by oral biologists in the University at Buffalo School of Dental Medicine has shown that passive exposure to tobacco smoke may increase the risk of developing gum detachment and bleeding gums in adults by up to 70 percent. (1999-03-12)

Blood type O patients may have higher risk of death from severe trauma
Blood type O is associated with high death rates in severe trauma patients, according to a study published in the open-access journal Critical Care that involved 901 Japanese emergency care patients. (2018-05-01)

Drug stops dangerous bleeding in patients taking factor Xa inhibitors
The experimental drug andexanet was associated with control of serious bleeding in patients taking a common class of anticoagulants known as Factor Xa inhibitors, according to interim clinical trial results presented at the American College of Cardiology's 67th Annual Scientific Session. Millions of patients take Factor Xa inhibitors, which elevate the risk of serious bleeding. (2018-03-12)

Penn Medicine GI bleeding research points to need for updated Medicare policies
Penn Medicine researchers are calling for greater precision in Medicare performance reporting for patients with GI bleeding following an evaluation of patients with the condition. (2018-06-05)

ESC focused update on dual antiplatelet therapy in coronary artery disease published today
The first ESC Focused Update on Dual Antiplatelet Therapy in Coronary Artery Disease is published online today in European Heart Journal,1 and on the ESC website.2 The document was developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). (2017-08-26)

How and why blood clots shrink
In an article published in Nature Communications, researchers at the University of California, Riverside and the University of Pennsylvania School of Medicine used high-powered microscopy and rheometry -- the measurement of how materials become deformed in response to applied force -- to view the blood clotting process in real time and at the cellular level. The findings will be useful in the development of new therapies for clotting disorders. (2017-11-09)

Cilostazol-combo antiplatelet therapy reduced risk for recurrent stroke
The long-term combination of cilostazol with aspirin or clopidogrel resulted in fewer recurrent strokes than with aspirin or clopidogrel alone in high-risk patients. (2019-02-06)

Designing drugs and their antidotes together improves patient care
Imagine a surgical patient on a blood-thinning drug who starts bleeding more than expected, and an antidote that works immediately -- because the blood thinner and antidote were designed to work together. Researchers at Duke University Medical Center have engineered a way to do this for an entire, versatile class of drugs called aptamers and published their findings in Nature Medicine. (2009-10-04)

Researchers discover key pathway involved in blood vessel occlusion
Researchers have made a breakthrough in understanding blood vessel occlusion by discovering a novel pathway involved in this process. (2016-01-14)

Minimally invasive uterine fibroid treatment safer and as effective as surgical treatment
Uterine fibroid embolization (UFE) effectively treats uterine fibroids with fewer post-procedure complications compared to myomectomy, according to new research presented today at the Society of Interventional Radiology's 2019 Annual Scientific Meeting. Women who received this minimally-invasive treatment also had a slightly lower need for additional treatment than those who underwent surgery. (2019-03-25)

Rivaroxaban plus aspirin reduces adverse events (COMPASS)
Rivaroxaban plus aspirin reduces major adverse cardiovascular and limb events by nearly one-third in patients with peripheral artery disease, according to late-breaking results from the COMPASS trial presented today in a Hot Line -- LBCT Session at ESC Congress. (2017-08-27)

Management and outcomes of aortic dissection in pregnancy with Marfan Syndrome
In Marfan Syndrome (MFS), aortic dilatation is one of the main cardiovascular manifestations which deteriorate due to the physiological changes during pregnancy. We aimed to assess the up-to-date management and outcomes of aortic root dilation and dissection (AoD) in pregnancy with MFS (2019-04-18)

Automation speeds clinical safety surveillance
Using patient outcomes data from approximately 1,800 hospitals, the largest demonstration to date of automated safety surveillance of a medical device is reported in this week's New England Journal of Medicine. (2017-01-25)

Acute coronary syndromes -- Did prasugrel & ticagrelor offer same benefits as clopidogrel?
In patients presenting with acute coronary syndromes (ACS) either with or without ST-segment elevation MI (STEMI and NSTEMI), dual antiplatelet therapy (DAPT) is recommended for at least 1 year independently of whether revascularization is performed. (2018-02-07)

Self-sealing miniature 'wound' created by engineers
Biomedical engineers have developed a miniature self-sealing model system for studying bleeding and the clotting of wounds. The researchers envision the device as a drug discovery platform and potential diagnostic tool. (2018-02-07)

Stroke prevention drug combo shows promise, study says
If you've had a minor stroke or a transient ischemic stroke (TIA), taking the clot-preventing drug clopidogrel along with aspirin may lower your risk of having a major stroke within the next 90 days, according to new research published in The New England Journal of Medicine. (2018-05-16)

Investigators chart microbial ecology of gingivitis, periodontitis
Gingivitis, a common and mild form of gum disease can progress to periodontitis, a more serious infection that damages the soft tissue of the gums and sometimes even destroys the bone supporting the teeth. An international team of researchers and clinicians has charted the microbial ecology of the mouth at all stages of this progression, in nearly 1,000 women in Malawi. This work is laying a foundation of knowledge that could lead to better oral health. (2016-08-12)

Towards a sensor you could swallow to detect gut-related woes, in real time
A newly developed device could one day detect the presence of disease-driving molecules in the gut -- an otherwise difficult-to-access environment -- reading out these results to a cell phone in real time. (2018-05-24)

Platelet doppelgängers tackle thrombosis and cancer metastasis
Anne-Laure Papa and colleagues have created decoys of platelets -- the body's clot-forming blood cells -- that prevented the formation of dangerous blood clots in vessels (or thrombosis) and combated cancer metastasis in preclinical models. (2019-02-13)

FDA clears Berlex Laboratories' Mirena (R), new form of long-acting contraception meets need for U.S. women
U.S. Food and Drug Administration approved MIRENA (R)(levonorgestrel-releasing intrauterine system), a convenient, innovative contraceptive that is as effective in preventing pregnancy as tubal ligation (better than 99 percent) and lasts for five years or until removed. Two million women worldwide use MIRENA. Available for 10 years in Europe, MIRENA will be available in the U.S. in the first quarter of 2001. (2000-12-06)

Genetic testing helps set safe dose of common blood thinner
A new study led by Washington University School of Medicine in St. Louis shows that dosing warfarin (Coumadin and others) is safer -- producing fewer adverse events such as hemorrhage -- when key elements of a patient's genetic makeup are considered. (2017-09-26)

OHSU Researchers Find Estrogen/Progestin Therapy More Beneficial Than Estrogen Alone
Researchers at Oregon Health Sciences University have discovered that a new hormonal drug combination allows post-menopausal women to get the benefits of estrogen without experiencing the side effects of menses-like bleeding. Their findings appear in the Nov. 6, 1996 issue of the Journal of the American Medical Association (1996-11-01)

'Invisible' stool blood linked to heightened risk of death from all causes
'Invisible' blood detected in the stools is linked to a heightened risk of death from all causes, as well as from bowel cancer, reveals research published online in the journal Gut. (2018-07-16)

Impaired mental status is associated with doubled death risk after heart attack in elderly
Impaired mental status is associated with a doubled risk of death one year after a heart attack in elderly patients, according to research presented today at ESC Congress 2018. (2018-08-26)

Bleeding during endoscopy: Do anti-inflammatories play a role?
Does an aspirin-a-day increase the risk of bleeding during invasive diagnostic procedure? This is an important concern for many patients who take these and other antiplatelet agents in an effort to reduce heart attacks or strokes. Researchers at the MUHC have shown that antiplatelet drugs do not contribute to post-endoscopic bleeding. Their findings are published in this month's issue of Alimentary Pharmacology and Therapeutics. (2007-03-15)

New anti-clotting drugs linked to lower risk of serious bleeding
New drugs known as direct oral anticoagulants (DOACs) used to treat serious blood clots are associated with reduced risks of major bleeding compared with the older anti-clotting drug, warfarin, finds a study in The BMJ today. (2018-07-04)

New insights into how to protect premature babies from common brain disorder
Premature babies have delicate brain tissue that is prone to bleeding and can result in post-hemorrhagic hydrocephalus, a dangerous condition that leads to excess fluid accumulation and brain dysfunction. Now, scientists from Sanford Burnham Prebys Medical Discovery Institute have identified a new disease mechanism and potential molecular drug target that may protect premature newborns from developing the brain disorder. The study was published in Science Advances. (2019-10-09)

Lung cancer: Less invasive surgery for faster recovery
Every day, 78 Canadians receive a diagnosis of lung cancer, the most deadly form of cancer. Some will have one lobe of a lung removed. The results of a large international clinical study led by Dr. Moishe Liberman, paves the way for the widespread of thoracoscopic lobectomy -- video-assisted thoracoscopic surgery (VATS) -- combined with pulmonary artery sealing using an ultrasonic energy device. This technique reduce the risk of post-operative bleeding, complications and pain for patients. (2019-05-04)

Apixaban plus P2Y12 inhibitor and no aspirin safest for patients with both AFib and ACS
Patients at high risk for heart attacks, strokes and blood clots who were treated with a novel blood thinner (apixaban) and an antiplatelet drug such as clopidogrel had a significantly lower risk of bleeding and being hospitalized compared with patients who received an older blood-thinning medication such as warfarin, according to research presented at the American College of Cardiology's 68th Annual Scientific Session. (2019-03-18)

Does gingko biloba affect memory?
Taking the supplement ginkgo biloba had no clear-cut benefit on the risk of developing memory problems, according to a study published in the Feb. 27, 2008, online issue of Neurology, the medical journal of the American Academy of Neurology. (2008-02-27)

U-M sibling study discovers genetic region linked to control of key blood-clotting protein
In 2006, the lab of Dr. David Ginsburg at the Life Sciences Institute put a call out for siblings attending the University of Michigan to donate blood for a study of blood-clotting disorders. (2013-01-08)

For patients with diabetes, ticagrelor reduced heart attacks, strokes
In late-breaking clinical trial results presented in a Hot Line Session today at the European Society of Cardiology Congress 2019, investigators from Brigham and Women's Hospital and Greater Paris University Hospitals -- AP-HP/Université de Paris presented the results from The Effect of Ticagrelor on Health Outcomes in Diabetes Mellitus Patients Intervention Study (THEMIS). (2019-09-01)

Protein derived from parasite has potential to alleviate debilitating disease
A Children's-led research team has turned the tables on Schistosoma haematobium, a parasitic worm that freeloads in humans, by using a protein derived from the parasite as a therapeutic molecule to reduce bleeding and pain associated with chemotherapy-induced hemorrhagic cystitis. (2018-04-03)

One monoclonal antibody protects against 2 lethal viruses
A new study reports that one human monoclonal antibody therapy protected nonhuman primates from the lethal hemorrhagic fevers caused by both Marburg and Ravn viruses. (2017-04-05)

Personalized approach to selecting antiplatelet drugs improves outcomes
Patients with acute coronary syndrome experienced a substantially lower rate of heart attack, stroke, death from cardiovascular causes and major bleeding at 12 months if genetic information was used to inform the selection of their antiplatelet medication in a study presented at the American College of Cardiology's 67th Annual Scientific Session. (2018-03-11)

Aspirin should not be recommended for healthy people over 70
Low-dose aspirin does not prolong disability-free survival of healthy people over 70, even in those at the highest risk of cardiovascular disease. The late breaking results of the ASPREE trial are presented today at ESC Congress 2019 together with the World Congress of Cardiology. (2019-08-31)

Using genetics to guide warfarin dosing after hip, knee replacement
Among patients undergoing hip or knee replacement and treated with the blood thinner warfarin, customizing dosing to a patient's genetic and clinical profile resulted in the prevention of more adverse outcomes than clinically-guided dosing, according to a study published by JAMA. (2017-09-26)

Cancer fighting effects of aspirin revealed in bowel tumor study
Researchers at the University of Edinburgh have shed light on how taking aspirin can help to stave off bowel cancer. (2018-06-04)

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