Popular Breast Cancer News and Current Events

Popular Breast Cancer News and Current Events, Breast Cancer News Articles.
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Outcompeting cancer
Suppressing the capacity of tumors to destroy the healthy tissue that surrounds them is essential for fighting cancer-induced morbidity and mortality. Now, a new study in human-derived tumors reveals a potential way of doing just that. The study reveals a competition mechanism used by human cancer cells for killing their neighbors and demonstrates that combining substances that block this mechanism with chemotherapy results in more effective tumor elimination. These findings may lead to the development of novel cancer therapies. (2019-07-24)

Eight of 10 people with cancer risk genes don't know it
Genomic screening of more than 50,000 people shows that more than 80 percent of those who carry an identifiable genetic risk for breast, ovarian, prostate, and pancreatic cancer don't know it despite frequent interaction with the healthcare system. (2018-09-21)

MD Anderson study evaluates need for biopsies during follow-up care in women with early breast cancer
In an analysis of more than 120,000 women diagnosed with and treated for early-stage breast cancer, researchers from The University of Texas MD Anderson Cancer Center determined the rate of additional breast biopsies needed for these patients during their follow-up care. The findings, reported in JAMA Surgery, are the first comprehensive nationwide population-based study regarding the need for breast biopsies performed during follow up after treatment for invasive breast cancer. (2018-01-31)

Complex cellular machine visualized to yield new insights in cancer
Cellular machines that control chromosome structure, such as the RSC complex, are mutated in about one-fifth of all human cancers. Now, for the first time, scientists have developed a high-resolution visual map of this multi-protein machine, elucidating how the RSC complex works and what role it has in healthy and cancer cells. (2019-10-31)

NUS scientists combine antimalarial drug with light sensitive molecules for promising treatment of cancer
NUS scientists discovered that a combination of artemisinin, which is a potent anti-malarial drug, and aminolaevulinic acid, which is a photosensitizer, could kill colorectal cancer cells and suppress tumor growth more effectively than administering artemisinin alone. This novel combination therapy could also have fewer side effects. (2017-09-18)

Radiotherapy for invasive breast cancer increases the risk of second primary lung cancer
East Asian female breast cancer patients receiving radiotherapy have a higher risk of developing second primary lung cancer. (2017-02-15)

Cancer genomics continued: Triple negative breast cancer and cancer immunotherapy
Continuing PLOS Medicine's special issue on cancer genomics, Christos Hatzis of Yale University, New Haven, Conn., USA and colleagues describe a new subtype of triple negative breast cancer that may be more amenable to treatment than other cases of this difficult-to-treat disease. (2016-12-13)

Metabolite that promotes cancer cell transformation and colorectal cancer spread identified
Osaka University researchers revealed that the metabolite D-2-hydroxyglurate (D-2HG) promotes epithelial-mesenchymal transition of colorectal cancer cells, leading them to develop features of lower adherence to neighboring cells, increased invasiveness, and greater likelihood of metastatic spread. The finding highlights the value of targeting D-2HG to establish new therapeutic approaches against colorectal cancer. (2016-12-01)

US Preventive Services Task Force recommendation statement on behavioral counseling to prevent skin cancer
The US Preventive Services Task Force (USPSTF) recommends behavioral counseling to help reduce the risk of skin cancer from ultraviolet (UV) radiation in persons ages 6 months to 24 years with fair skin types. (2018-03-20)

Does MRI plus mammography improve detection of new breast cancer after breast conservation therapy?
A new article published by JAMA Oncology compares outcomes for combined mammography and MRI or ultrasonography screenings for new breast cancers in women who have previously undergone breast conservation surgery and radiotherapy for breast cancer initially diagnosed at 50 or younger. (2017-06-22)

Radiotherapy for lung cancer patients is linked to increased risk of non-cancer deaths
Researchers have found that treating patients who have early stage non-small cell lung cancer with a type of radiotherapy called stereotactic body radiation therapy is associated with a small but increased risk of death from causes other than cancer. The findings are presented at the annual meeting of the European Society for Radiotherapy and Oncology - ESTRO35. (2016-05-01)

Oncotarget: Researchers identify a potential molecular trigger for invasiveness in prostate cancer cells
A small protein modification can trigger the aggressive migratory and invasive properties of prostate cancer cells, according to new research published on the cover of Oncotarget. The findings give greater insight into how cancers can move from one location in the body to another, and could help develop more effective therapies in the future. Editorial by Xin Ye and Robert A. Weinberg can be found online. (2017-11-20)

Racial differences in age at breast cancer diagnosis challenges use of single age-based screening guidelines
Among women in the US diagnosed with breast cancer, a higher proportion of nonwhite patients were diagnosed at younger than 50 years of age compared to white patients, suggesting that age-based screening guidelines that do not account for race may result in underscreening of nonwhite women. (2018-03-07)

UI Cancer Center, Governors State to address cancer disparities in south suburbs
The University of Illinois Cancer Center and Governors State University have received a joint four-year, $1.5 million grant from the National Cancer Institute to help both institutions conduct community-based research to reduce cancer-related health disparities in Chicago's south suburbs. (2015-10-13)

Blood test offers improved breast cancer detection tool to reduce use of breast biopsy
A Clinical Breast Cancer study demonstrates Videssa Breast can inform better next steps after abnormal mammogram results and potentially reduce biopsies up to 67 percent. (2017-05-23)

Delaying adjuvant chemo associated with worse outcomes for patients with triple-negative breast cancer
Patients with triple-negative breast cancer who delayed starting adjuvant chemotherapy for more than 30 days after surgery were at significantly higher risk for disease recurrence and death compared with those who started the treatment in the first 30 days after surgery, according to a retrospective study presented at the 2018 San Antonio Breast Cancer Symposium. (2018-12-05)

Prognostic role of elevated mir-24-3p in breast cancer
Using nanostring and RNA-sequencing technologies researchers from the NYU School of Medicine, the Perlmutter Cancer Center, UT MD Anderson Cancer Center, and the University of Massachusetts Medical School identified mi R-24-3p as a potential novel marker of breast cancer metastases in breast cancer. (2018-03-01)

Breast cancer statistics, 2017
Breast cancer death rates dropped 39 percent between 1989 and 2015, averting 322,600 breast cancer deaths during those 26 years. Death rates in several states are now statistically equivalent, perhaps reflecting an elimination of disparities in those states. (2017-10-03)

Enzyme may get key role in drug design for breast cancer and brain condition
In recent years, researchers have focused on the enzyme TLK2 suspecting it of playing a main role in several diseases. A new study conducted at the University of Copenhagen now reveals that the enzyme displays lower levels of activity in intellectual disability and that it is possible to inhibit it in breast cancer, where it is overactive. The study thus suggests that the enzyme may be a target for potential therapies. (2018-06-29)

Many women diagnosed with cancer have sexual health concerns
A new review published in the European Journal of Cancer Care indicates that, in women diagnosed with cancer, concerns pertaining to sexual health are diverse, multiple, and pervade all types and stages of cancer. (2017-08-11)

Avoiding obesity and maintaining stable weight both important in preventing several obesity-related cancers in women
Avoiding obesity as well as maintaining a stable weight in middle adulthood could help prevent certain cancers in women, according to new research presented at this year's European Conference on Obesity (ECO) in Vienna, Austria (May 23-26). (2018-05-23)

Study shows high phenolic acid intake -- associated with a healthy diet -- is associated with reduced breast cancer risk
New research presented at this year's European Congress on Obesity (ECO) in Glasgow, Scotland (April 28-May 1) shows that a high intake of phenolic acids -- associated with a healthy diet -- is associated with a decreased risk of postmenopausal breast cancer. The study is by Andrea Romanos Nanclares, University of Navarra, Pamplona, Spain, and colleagues. (2019-04-30)

Breathing during radiotherapy - how to hit the treatment target without causing collateral damage
Respiratory movement during radiotherapy makes it difficult to hit the right treatment target and this in turn can lead to an under-dose of radiation to the tumor, or a potentially toxic over-dose to the surrounding healthy tissue. Getting this right is a real challenge for the radiotherapist, but new techniques are helping to deliver the correct dose to the right place. (2012-05-11)

Huntington's disease provides new cancer weapon
Patients with Huntington's disease, a fatal genetic illness that causes the breakdown of nerve cells in the brain, have up to 80 percent less cancer than the general population. Scientists have discovered why Huntington's is so toxic to cancer cells and harnessed it for a novel approach to treat cancer, a new study reports. (2018-02-12)

The clinical and biological significance of HER2 over-expression in breast ductal carcinoma in situ: A large study from a single institution
Upcoming publication from the British Journal of Cancer, investigating HER2 expression as a predictor of recurrence and development in patients with DCIS. (2019-05-07)

Engineering a new cancer detection tool
E. coli may have potentially harmful effects but scientists in Australia have discovered this bacterium produces a toxin which binds to an unusual sugar that is part of carbohydrate structures present on cells not usually produced by healthy cells. This structure is a known tumor antigen leading scientists to develop a new cancer detection tool. (2017-06-07)

African-American women with type 2 diabetes may have higher risk for ER-neg breast cancer
Among African-American women, those with type 2 diabetes may have a higher risk of developing estrogen receptor (ER)-negative breast cancer. (2017-11-15)

One-third of breast cancer patients not getting appropriate breast imaging follow-up exam
An annual mammogram is recommended after treatment for breast cancer, but nearly one-third of women diagnosed with breast cancer aren't receiving this follow-up exam, according to new findings presented at the 2016 Annual Clinical Congress of the American College of Surgeons. (2016-10-19)

A protein that stem cells require could be a target in killing breast cancer cells
Researchers have identified a protein that must be present in order for mammary stem cells to perform their normal functions. When the researchers genetically removed or chemically inhibited the protein, called BPTF, stem cells could no longer maintain their 'renewing' state and began to take on the character of specialized breast cells, and soon died. Breast cancer cells with stem-like properties could have the same weakness. (2017-06-01)

Androgen receptor targeted imaging of prostate cancer as future modality for diagnosis
Future direction in prostate cancer imaging involves the development of androgen receptor based imaging using nonsteroidal antiandrogen agent for early diagnosis of prostate cancer. (2017-10-06)

Type 2 diabetes associated with risk of aggressive breast cancer in black women
African American women with type 2 diabetes (often referred to as adult-onset diabetes) are at a greater risk for developing breast cancer. (2017-11-15)

Surgery to remove unaffected breast in early breast cancer increases
The proportion of women in the United States undergoing surgery for early-stage breast cancer who have preventive mastectomy to remove the unaffected breast increased significantly in recent years, particularly among younger women, and varied substantially across states. (2017-03-29)

Epigenetic editing reveals surprising insights into early breast cancer development
Changing the epigenetic code of a single gene is enough to cause a healthy breast cell to begin a chain reaction and become abnormal, according to research by Queen Mary University of London (QMUL). (2017-11-13)

Acupuncture significantly reduces joint pain for breast cancer patients
In the largest, most rigorous study of its kind, acupuncture was found to significantly reduce the debilitating joint pain experienced by tens of thousands of women each year while being treated for early stage breast cancer, according to SWOG research results to be announced at a Dec. 7 press conference at the San Antonio Breast Cancer Symposium. (2017-12-07)

Study finds people with type 2 diabetes at higher risk of death from both obesity-related and non-obesity related cancers
Being overweight or obese may put adults with diabetes at greater risk of dying from cancer than their diabetes-free counterparts, particularly for obesity-related cancers such as those arising from the bowel, kidney, and pancreas in men and women, and from the breast and endometrium (lining of the uterus) in women. (2018-10-02)

Some early breast cancer patients benefit more from breast conservation than from mastectomy
Breast conserving therapy (BCT) is better than mastectomy for patients with some types of early breast cancer, according to results from the largest study to date, presented at ECC2017. Dutch researchers report that considerably superior survival, both specific to breast cancer and from any cause of death, was found among certain groups of patients who had had BCT. (2017-01-29)

Hitgen and Cancer Research UK's Manchester Institute enter license agreement in lung cancer
Cancer Research UK, Cancer Research Technology (CRT), the charity's commercial arm, and HitGen Ltd, a privately held biotech company focused on early drug discovery, announced today that they have entered into a licence agreement to develop a novel class of drugs against lung cancer. (2017-02-27)

What is association of radioactive iodine treatment for overactive thyroid with risk of cancer death?
Radioactive iodine has been used since the 1940s to treat hyperthyroidism, an overactive thyroid. This study is an extension of one that has followed patients in the United States and the United Kingdom treated for hyperthyroidism for nearly 70 years. Researchers sought to determine the association of doses of radioactive iodine absorbed by organs or tissue with overall and site-specific cancer death. (2019-07-01)

Full dose radiotherapy to whole breast may not be needed in early breast cancer
Five years after breast-conserving surgery, radiotherapy focused around the tumor bed is as good at preventing recurrence as irradiating the whole breast, with fewer side effects, researchers from the UK have found in the large IMPORT LOW trial. (2016-03-09)

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment. (2018-10-05)

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