Popular Cancer Cells News and Current Events

Popular Cancer Cells News and Current Events, Cancer Cells News Articles.
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Outcompeting cancer
Suppressing the capacity of tumors to destroy the healthy tissue that surrounds them is essential for fighting cancer-induced morbidity and mortality. Now, a new study in human-derived tumors reveals a potential way of doing just that. The study reveals a competition mechanism used by human cancer cells for killing their neighbors and demonstrates that combining substances that block this mechanism with chemotherapy results in more effective tumor elimination. These findings may lead to the development of novel cancer therapies. (2019-07-24)

Eight of 10 people with cancer risk genes don't know it
Genomic screening of more than 50,000 people shows that more than 80 percent of those who carry an identifiable genetic risk for breast, ovarian, prostate, and pancreatic cancer don't know it despite frequent interaction with the healthcare system. (2018-09-21)

The unveiling of a novel mechanism of resistance to immunotherapy targeting HER2
VHIO investigators report how HER2 breast cancer cells adopt a strategy to resist clearance by redirected lymphocytes. Findings evidence that the disruption of interferon-gamma signaling confers resistance to these immunotherapies and promotes disease progression. Reported in Nature Communications, these results could help to potentiate future immune-based strategies and more precisely identify those patients who would be most likely to benefit from them. (2021-02-23)

Targeted delivery of highly toxic anti-cancer drug to brain tumors
University of Houston biomedical researcher Sheeren Majd is reporting the development and testing of a new nano-carrier as a potential treatment to deliver highly toxic medicine to glioblastomas, the most common and aggressive form of primary brain tumors. (2021-02-23)

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment. (2018-10-05)

Study shows new treatment pathway to prevent and treat endometrial cancer recurrence
In a new study led by Yale Cancer Center, researchers demonstrate sex hormones and insulin growth factors are associated with recurrence risk of endometrial cancer. (2021-02-23)

Sound waves could provide 'liquid biopsies'
Using sound waves, researchers have developed a gentle, contact-free method for separating circulating tumor cells from blood samples that is fast and efficient enough for clinical use. The ability to quickly and efficiently harvest and grow these cells from a blood sample would enable 'liquid biopsies' capable of providing individualized diagnosis, prognosis and suggestions for treatment strategies. (2018-07-03)

Mayo discovery means individualized ovarian, brain cancer therapies
Mayo Clinic researchers have discovered that a molecular communication pathway -- thought to be defective in cancer -- is a key player in determining the effectiveness of measles virus oncolytic cancer treatment in ovarian and aggressive brain cancers. This discovery enabled researchers to develop an algorithm to predict treatment effectiveness in individual patients. The findings appear in the Journal of the National Cancer Institute. (2018-05-16)

Stealth virus for cancer therapy
Scientists from the University of Zurich have redesigned an adenovirus for use in cancer therapy. To achieve this they developed a new protein shield that hides the virus and protects it from being eliminated. Adapters on the surface of the virus enable the reconstructed virus to specifically infect tumor cells. (2018-01-31)

Complex cellular machine visualized to yield new insights in cancer
Cellular machines that control chromosome structure, such as the RSC complex, are mutated in about one-fifth of all human cancers. Now, for the first time, scientists have developed a high-resolution visual map of this multi-protein machine, elucidating how the RSC complex works and what role it has in healthy and cancer cells. (2019-10-31)

Penn-developed approach could limit toxicity of CAR T therapy in acute myeloid leukemia
A new approach pioneered at the University of Pennsylvania's Abramson Cancer Center may provide a new path towards treating acute myeloid leukemia (AML) with CAR T cells. (2018-05-31)

UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies
A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy. (2020-06-12)

American Cancer Society outlines blueprint for cancer control in the 21st century
The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that forms the basis of a national cancer control plan. (2018-07-10)

Distinguishing fatal prostate cancer from 'manageable' cancer now possible
Scientists at the University of York have found a way of distinguishing between fatal prostate cancer and manageable cancer, which could reduce unnecessary surgeries and radiotherapy. (2018-10-18)

Zika vaccine shows promise for treating deadly brain cancer
An international team of researchers has successfully deployed a Zika virus vaccine to target and kill human glioblastoma brain cancer stem cells, which had been transplanted into mice. In a study published this week in mBio®, the team shows that a live, attenuated version of the Zika virus could form the basis of a new treatment option for this fatal brain cancer. (2018-09-18)

NUS scientists combine antimalarial drug with light sensitive molecules for promising treatment of cancer
NUS scientists discovered that a combination of artemisinin, which is a potent anti-malarial drug, and aminolaevulinic acid, which is a photosensitizer, could kill colorectal cancer cells and suppress tumor growth more effectively than administering artemisinin alone. This novel combination therapy could also have fewer side effects. (2017-09-18)

Metabolite that promotes cancer cell transformation and colorectal cancer spread identified
Osaka University researchers revealed that the metabolite D-2-hydroxyglurate (D-2HG) promotes epithelial-mesenchymal transition of colorectal cancer cells, leading them to develop features of lower adherence to neighboring cells, increased invasiveness, and greater likelihood of metastatic spread. The finding highlights the value of targeting D-2HG to establish new therapeutic approaches against colorectal cancer. (2016-12-01)

Moffitt Cancer Center researchers identify one way T cell function may fail in cancer
Moffitt Cancer Center researchers have discovered a mechanism by which one type of immune cell, CD8+ T cells, can become dysfunctional, impeding its ability to seek and kill cancer cells. (2019-04-04)

Sensor could help doctors select effective cancer therapy
MIT chemical engineers have developed a sensor that lets them see hydrogen peroxide inside cancer cells and determine whether they are responding to drugs that affect redox signaling. (2018-08-07)

US Preventive Services Task Force recommendation statement on behavioral counseling to prevent skin cancer
The US Preventive Services Task Force (USPSTF) recommends behavioral counseling to help reduce the risk of skin cancer from ultraviolet (UV) radiation in persons ages 6 months to 24 years with fair skin types. (2018-03-20)

New analytical technology to quantify anti-cancer drugs inside cancer cells
University of Oklahoma researchers will apply a new analytical technology that could ultimately provide a powerful tool for improved treatment of cancer patients in Oklahoma and beyond. Using mass spectrometry, an analytical instrument for sensitive detection and accurate identification of molecules, the team will quantitate the amount of anti-cancer drugs present in individual cancer cells, including those in bladder cancer cells isolated from patients undergoing chemotherapy. (2016-06-14)

Breast cancer treatment costs highest among young women with metastic cancer
In a fight for their lives, young women, age 18-44, spend double the amount of older women to survive metastatic breast cancer, according to a large statewide study by the University of North Carolina at Chapel Hill. (2020-06-10)

UC San Diego cancer scientists identify new drug target for multiple tumor types
A dysfunctional enzyme involved in building cancer cell membranes helps fuel tumor growth; when it's disabled or depleted in mouse models, tumors shrank significantly. (2019-07-11)

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications. (2020-10-22)

UH Cancer Center researcher finds new driver of an aggressive form of brain cancer
University of Hawai'i Cancer Center researchers have identified an essential driver of tumor cell invasion in glioblastoma, the most aggressive form of brain cancer that can occur at any age. The discovery can help researchers create novel targeted therapies potentially reducing deaths from this devastating cancer. (2016-11-14)

Oncotarget: Researchers identify a potential molecular trigger for invasiveness in prostate cancer cells
A small protein modification can trigger the aggressive migratory and invasive properties of prostate cancer cells, according to new research published on the cover of Oncotarget. The findings give greater insight into how cancers can move from one location in the body to another, and could help develop more effective therapies in the future. Editorial by Xin Ye and Robert A. Weinberg can be found online. (2017-11-20)

Novel technology for anticancer drug delivery on demand
With the goal of minimizing the side effects of chemotherapy on healthy tissues, IBS scientists have developed novel nanocontainers able to deliver anticancer drugs at precise timing and location. They combines uniquely designed molecules and light-dependent drug release, which may provide a new platform to enhance the effect of anticancer therapeutics. (2018-03-09)

Lung transplant patients face elevated lung cancer risk
In an American Journal of Transplantation study, lung cancer risk was increased after lung transplantation, especially in the native (non-transplanted) lung of single lung transplant recipients. (2018-12-19)

MicroRNA could help treat cancer and asthma
MiR-223 shows promise for treating inflammatory disease. (2018-02-20)

Prognostic role of elevated mir-24-3p in breast cancer
Using nanostring and RNA-sequencing technologies researchers from the NYU School of Medicine, the Perlmutter Cancer Center, UT MD Anderson Cancer Center, and the University of Massachusetts Medical School identified mi R-24-3p as a potential novel marker of breast cancer metastases in breast cancer. (2018-03-01)

Engineering researchers use laser to 'weld' neurons
University of Alberta researchers have developed a method of connecting neurons, using ultrashort laser pulses -- a breakthrough technique that opens the door to new medical research and treatment opportunities. Neurons are cells in the nervous system that are responsible for transferring information between the brain and the rest of the body. The team is the first ever to find a way to bond neurons and in doing so, is giving researchers a powerful new tool. (2016-02-09)

Breast cancer statistics, 2017
Breast cancer death rates dropped 39 percent between 1989 and 2015, averting 322,600 breast cancer deaths during those 26 years. Death rates in several states are now statistically equivalent, perhaps reflecting an elimination of disparities in those states. (2017-10-03)

Enhanced glow
Tumor cells circulating in blood are markers for the early detection and prognosis of cancer. However, detection of these cells is challenging because of their scarcity. In the journal Angewandte Chemie, scientists have now introduced an ultrasensitive method for the direct detection of circulating tumor cells in blood samples. It is based on the amplified, time-resolved fluorescence measurement of luminescent lanthanide ions released from nanoparticles that bind specifically to tumor cells. (2019-08-07)

Huntington's disease provides new cancer weapon
Patients with Huntington's disease, a fatal genetic illness that causes the breakdown of nerve cells in the brain, have up to 80 percent less cancer than the general population. Scientists have discovered why Huntington's is so toxic to cancer cells and harnessed it for a novel approach to treat cancer, a new study reports. (2018-02-12)

Enzyme may get key role in drug design for breast cancer and brain condition
In recent years, researchers have focused on the enzyme TLK2 suspecting it of playing a main role in several diseases. A new study conducted at the University of Copenhagen now reveals that the enzyme displays lower levels of activity in intellectual disability and that it is possible to inhibit it in breast cancer, where it is overactive. The study thus suggests that the enzyme may be a target for potential therapies. (2018-06-29)

Many women diagnosed with cancer have sexual health concerns
A new review published in the European Journal of Cancer Care indicates that, in women diagnosed with cancer, concerns pertaining to sexual health are diverse, multiple, and pervade all types and stages of cancer. (2017-08-11)

Engineering a new cancer detection tool
E. coli may have potentially harmful effects but scientists in Australia have discovered this bacterium produces a toxin which binds to an unusual sugar that is part of carbohydrate structures present on cells not usually produced by healthy cells. This structure is a known tumor antigen leading scientists to develop a new cancer detection tool. (2017-06-07)

Researchers are first to see DNA 'blink'
Northwestern University biomedical engineers have developed imaging technology that is the first to see DNA 'blink,' or fluoresce. The tool enables researchers to study individual biomolecules (DNA, chromatin, proteins) as well as important global patterns of gene expression, which could yield insights into cancer. Vadim Backman will discuss the technology and its applications -- including the new concept of macrogenomics, a technology aiming to regulate the global patterns of gene expression without gene editing -- at the 2017 AAAS annual meeting. (2017-02-17)

Avoiding obesity and maintaining stable weight both important in preventing several obesity-related cancers in women
Avoiding obesity as well as maintaining a stable weight in middle adulthood could help prevent certain cancers in women, according to new research presented at this year's European Conference on Obesity (ECO) in Vienna, Austria (May 23-26). (2018-05-23)

The development of brain stem cells into new nerve cells and why this can lead to cancer
Stem cells are true Jacks-of-all-trades of our bodies, as they can turn into the many different cell types of all organs. This allows the tissues to renew and to heal after injury. This amazing multipotency makes stem cells in the adult body key tools for regenerative medicine. Scientists at the German Cancer Research Center (DKFZ) now publish in the journal Nature how brain stem cells make the decision to transform into new nerve cells. (2019-01-31)

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