Popular Cancer Diagnosis News and Current Events

Popular Cancer Diagnosis News and Current Events, Cancer Diagnosis News Articles.
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Not silent at all
The so-called 'silent' or 'synonymous' genetic alterations do not result in altered proteins. But they can nevertheless influence numerous functions of the cell and thus also disease processes. Scientists from the German Cancer Consortium, German Cancer Research Center, and the University of Freiburg have now created a comprehensive database of all synonymous mutations ever found in cancer. This is a 'reference book' that provides cancer researchers with all available information on each of these supposedly 'silent' mutations at a glance. (2019-06-12)

IMpower131
Patients with Stage IV squamous non-small cell lung cancer enrolled in clinical trial to test the immunotherapy atezolizumab and chemotherapy against chemotherapy alone experienced a longer survival rate, among a subgroup of patients with high PD-LI. (2019-09-10)

Eight of 10 people with cancer risk genes don't know it
Genomic screening of more than 50,000 people shows that more than 80 percent of those who carry an identifiable genetic risk for breast, ovarian, prostate, and pancreatic cancer don't know it despite frequent interaction with the healthcare system. (2018-09-21)

Genetic tool improves estimation of prostate cancer risk in diverse ethnic/racial groups
Scientists at University of California San Diego School of Medicine validated a more inclusive and comprehensive genetic tool, known as a polygenic hazard score (PHS), for predicting age of onset of aggressive prostate cancer. (2021-02-23)

Sound waves could provide 'liquid biopsies'
Using sound waves, researchers have developed a gentle, contact-free method for separating circulating tumor cells from blood samples that is fast and efficient enough for clinical use. The ability to quickly and efficiently harvest and grow these cells from a blood sample would enable 'liquid biopsies' capable of providing individualized diagnosis, prognosis and suggestions for treatment strategies. (2018-07-03)

BJC press notice
Please contact the BJC press office for the full paper or with any other questions on 0203 469 8300, out of hours, 07050 264 059 or bjcpress@cancer.org.uk. Scientists can be directly contacted regarding media interviews using the contact details provided. (2019-03-19)

MD Anderson study evaluates need for biopsies during follow-up care in women with early breast cancer
In an analysis of more than 120,000 women diagnosed with and treated for early-stage breast cancer, researchers from The University of Texas MD Anderson Cancer Center determined the rate of additional breast biopsies needed for these patients during their follow-up care. The findings, reported in JAMA Surgery, are the first comprehensive nationwide population-based study regarding the need for breast biopsies performed during follow up after treatment for invasive breast cancer. (2018-01-31)

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment. (2018-10-05)

Children with chronic illness often show signs of mental health problems
Researchers from the University of Waterloo surveyed children between the ages of six and 16, and all within a month of their diagnosis with asthma, food allergy, epilepsy, diabetes or juvenile arthritis. (2018-01-04)

NUS scientists combine antimalarial drug with light sensitive molecules for promising treatment of cancer
NUS scientists discovered that a combination of artemisinin, which is a potent anti-malarial drug, and aminolaevulinic acid, which is a photosensitizer, could kill colorectal cancer cells and suppress tumor growth more effectively than administering artemisinin alone. This novel combination therapy could also have fewer side effects. (2017-09-18)

Forgoing chemo linked to worse survival in older patients with advanced colon cancer who had dementia
A pre-existing diagnosis of dementia was associated with increased risk of death for older patients with advanced colon cancer; however, some of the effects of dementia on survival could be mediated by receipt of chemotherapy. (2017-09-22)

Metabolite that promotes cancer cell transformation and colorectal cancer spread identified
Osaka University researchers revealed that the metabolite D-2-hydroxyglurate (D-2HG) promotes epithelial-mesenchymal transition of colorectal cancer cells, leading them to develop features of lower adherence to neighboring cells, increased invasiveness, and greater likelihood of metastatic spread. The finding highlights the value of targeting D-2HG to establish new therapeutic approaches against colorectal cancer. (2016-12-01)

Study shows new treatment pathway to prevent and treat endometrial cancer recurrence
In a new study led by Yale Cancer Center, researchers demonstrate sex hormones and insulin growth factors are associated with recurrence risk of endometrial cancer. (2021-02-23)

US Preventive Services Task Force recommendation statement on behavioral counseling to prevent skin cancer
The US Preventive Services Task Force (USPSTF) recommends behavioral counseling to help reduce the risk of skin cancer from ultraviolet (UV) radiation in persons ages 6 months to 24 years with fair skin types. (2018-03-20)

Distinguishing fatal prostate cancer from 'manageable' cancer now possible
Scientists at the University of York have found a way of distinguishing between fatal prostate cancer and manageable cancer, which could reduce unnecessary surgeries and radiotherapy. (2018-10-18)

For patients with prostate cancer, dysfunction due to treatment side effects results in increased emotional distress -- and vice versa
A new study published in The Journal of Urology reports that men with prostate cancer who had worse urinary, bowel, and sexual function after surgery or radiotherapy than others experienced more emotional distress. Interestingly, the reverse was also true as experiencing more distress led to worse function. The likelihood of this reciprocal relationship highlights the importance of greater investment in psychosocial care to mitigate treatment side effects in prostate cancer survivors. (2018-05-31)

Relying on Dr. Google to diagnose eye problems may be dangerous to your health
A study examining the diagnoses generated by WebMD Symptom Checker showed the online tool was correct only 26 percent of the time. And the recommendation for the top diagnosis was often inappropriate, at times recommending self-care at home instead of going to the emergency room. (2018-10-29)

UH Cancer Center researcher finds new driver of an aggressive form of brain cancer
University of Hawai'i Cancer Center researchers have identified an essential driver of tumor cell invasion in glioblastoma, the most aggressive form of brain cancer that can occur at any age. The discovery can help researchers create novel targeted therapies potentially reducing deaths from this devastating cancer. (2016-11-14)

Cancer-sniffing dogs 97% accurate in identifying lung cancer, according to study in JAOA
The next step will be to further fractionate the samples based on chemical and physical properties, presenting them back to the dogs until the specific biomarkers for each cancer are identified. The goal is to develop an over-the-counter screening product, similar to a pregnancy test, in terms of cost, simplicity and availability. Dr. Quinn envisions a device that someone can breathe into and see a color change to indicate a positive or negative finding. (2019-06-17)

Racial differences in age at breast cancer diagnosis challenges use of single age-based screening guidelines
Among women in the US diagnosed with breast cancer, a higher proportion of nonwhite patients were diagnosed at younger than 50 years of age compared to white patients, suggesting that age-based screening guidelines that do not account for race may result in underscreening of nonwhite women. (2018-03-07)

Blood test offers improved breast cancer detection tool to reduce use of breast biopsy
A Clinical Breast Cancer study demonstrates Videssa Breast can inform better next steps after abnormal mammogram results and potentially reduce biopsies up to 67 percent. (2017-05-23)

Medicare claims show long-term prostate cancer prevention benefits of finasteride
Men who take the medication finasteride get a prostate cancer prevention benefit that can last 16 years -- twice as long as previously recorded, according to SWOG clinical trial analysis that made innovative use of Medicare data. (2018-03-20)

Prognostic role of elevated mir-24-3p in breast cancer
Using nanostring and RNA-sequencing technologies researchers from the NYU School of Medicine, the Perlmutter Cancer Center, UT MD Anderson Cancer Center, and the University of Massachusetts Medical School identified mi R-24-3p as a potential novel marker of breast cancer metastases in breast cancer. (2018-03-01)

Breast cancer statistics, 2017
Breast cancer death rates dropped 39 percent between 1989 and 2015, averting 322,600 breast cancer deaths during those 26 years. Death rates in several states are now statistically equivalent, perhaps reflecting an elimination of disparities in those states. (2017-10-03)

Energy dense foods may increase cancer risk regardless of obesity status
While there is a proven link between obesity and certain types of cancer, less is known about how the ratio of energy to food weight, otherwise known as dietary energy density (DED), contributes to cancer risk. To find out, researchers looked at DED in the diets of post-menopausal women and discovered that consuming high DED foods was tied to a 10 percent increase in obesity-related cancer among normal weight women. (2017-08-17)

Lung transplant patients face elevated lung cancer risk
In an American Journal of Transplantation study, lung cancer risk was increased after lung transplantation, especially in the native (non-transplanted) lung of single lung transplant recipients. (2018-12-19)

Overweight boys who have excessive weight gain during puberty at greater risk of colon cancer as adults
New research being presented at this year's European Congress on Obesity (ECO) in Vienna, Austria (May 23-26) suggests that being overweight in childhood coupled with excessive weight gain during puberty may contribute to the development of adult colon cancer in men. (2018-05-23)

American Cancer Society outlines blueprint for cancer control in the 21st century
The American Cancer Society is outlining its vision for cancer control in the decades ahead in a series of articles that forms the basis of a national cancer control plan. (2018-07-10)

Two studies explore gender, language, and treatment setting as barriers in screening and patient care in lung cancer
More people die of lung cancer than any other type of cancer, and two new studies from CHEST 2017 reveal disparities in lung cancer screening and care that may impact detection, as well as mortality and survival rates in the disease. (2017-10-23)

Many women diagnosed with cancer have sexual health concerns
A new review published in the European Journal of Cancer Care indicates that, in women diagnosed with cancer, concerns pertaining to sexual health are diverse, multiple, and pervade all types and stages of cancer. (2017-08-11)

Lung cancer may go undetected in kidney cancer patients
Could lung cancer be hiding in kidney cancer patients? Researchers with the Harold C. Simmons Comprehensive Cancer Center's Kidney Cancer Program studied patients with metastatic kidney cancer to the lungs and found that 3.5 percent of the group had a primary lung cancer tumor that had gone undiagnosed. This distinction can affect treatment choices and rates of survival. (2017-03-07)

Engineering a new cancer detection tool
E. coli may have potentially harmful effects but scientists in Australia have discovered this bacterium produces a toxin which binds to an unusual sugar that is part of carbohydrate structures present on cells not usually produced by healthy cells. This structure is a known tumor antigen leading scientists to develop a new cancer detection tool. (2017-06-07)

Heart failure after first heart attack may increase cancer risk
People who develop heart failure after their first heart attack have a greater risk of developing cancer when compared to first-time heart attack survivors without heart failure, according to a study today in the Journal of the American College of Cardiology. (2016-07-11)

AI helps to fight against lung cancer
Lung cancer has been the leading cause of cancer-related deaths in 2015 in United States. Early detection of lung nodules will undoubtedly increase the five-year survival rate for lung cancer according to prior studies. In a paper published in SCIENCE CHINA Information Sciences, researchers propose a novel rating method based on geometrical and statistical features to extract initial nodule candidates and an artificial neural network approach to the detection of lung nodules. (2017-06-29)

Avoiding obesity and maintaining stable weight both important in preventing several obesity-related cancers in women
Avoiding obesity as well as maintaining a stable weight in middle adulthood could help prevent certain cancers in women, according to new research presented at this year's European Conference on Obesity (ECO) in Vienna, Austria (May 23-26). (2018-05-23)

The clinical and biological significance of HER2 over-expression in breast ductal carcinoma in situ: A large study from a single institution
Upcoming publication from the British Journal of Cancer, investigating HER2 expression as a predictor of recurrence and development in patients with DCIS. (2019-05-07)

High EGFR expression a predictor for improved survival with cetuximab plus chemotherapy
High epidermal growth factor receptor (EGFR) expression was a good predictor of which lung cancer patients would survive longer when cetuximab (Erbitux) was added to first-line chemotherapy, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer. (2011-07-05)

African-American women with type 2 diabetes may have higher risk for ER-neg breast cancer
Among African-American women, those with type 2 diabetes may have a higher risk of developing estrogen receptor (ER)-negative breast cancer. (2017-11-15)

Androgen receptor targeted imaging of prostate cancer as future modality for diagnosis
Future direction in prostate cancer imaging involves the development of androgen receptor based imaging using nonsteroidal antiandrogen agent for early diagnosis of prostate cancer. (2017-10-06)

Surgery to remove unaffected breast in early breast cancer increases
The proportion of women in the United States undergoing surgery for early-stage breast cancer who have preventive mastectomy to remove the unaffected breast increased significantly in recent years, particularly among younger women, and varied substantially across states. (2017-03-29)

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