Popular Capsaicin News and Current Events

Popular Capsaicin News and Current Events, Capsaicin News Articles.
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Tree shrew tolerance for spicy foods unlocked by researchers
Researchers accidentally observed tree shrews directly and actively consuming chili peppers, despite the deep geographic isolation between the animal and the food. To understand this tolerance for spicy food, they performed genomic and functional analyses on the tree shrew and its TRPV1. (2018-07-13)

Leuven researchers uncover ion channel trio that mediates painful heat sensing
Researchers at VIB and KU Leuven have uncovered a trio of complementary ion channels in sensory neurons that mediate detection of acute, harmful heat. Having three redundant molecular heat-sensing mechanisms provides a powerful fail-safe mechanism that protects against burn injuries. The seminal findings have been published today in Nature. (2018-03-14)

New research reveals why chili peppers are hot
Despite the popularity of spicy cuisine among Homo sapiens, the hotness in chili peppers has always been something of an evolutionary mystery. (2008-08-11)

Hold the mustard: What makes spiders fussy eaters
It might be one of nature's most agile and calculating hunters, but the wolf spider won't harm an insect that literally leaves a bad taste in its mouth, according to new research by a team of Wake Forest University sensory neuroscientists, including C.J. Saunders. (2019-04-15)

'Holy powder' ingredient makes membranes behave for better health
Revered in India as (2009-03-06)

Anti-obesity drug derived from chili peppers shows promise in animal trials
A novel drug based on capsaicin, the compound that gives chili peppers their spicy burn, caused long term weight loss and improved metabolic health in mice eating a high fat diet, in new studies from the University of Wyoming School of Pharmacy. The drug, Metabocin, was designed to slowly release capsaicin throughout the day so it can exert its anti-obesity effect without producing inflammation or adverse side effects. (2018-07-17)

PIEZO2, a molecular target for treating clinical pain
The researchers think topical application of PIEZO2 blockers could be beneficial for patients suffering from neuropathic pain. (2018-10-10)

Research explains link between exercise and appetite loss
Ever wonder why intense exercise temporarily curbs your appetite? In research described in today's issue of PLOS Biology, Albert Einstein College of Medicine researchers reveal that the answer is all in your head -- more specifically, your arcuate nucleus. (2018-04-24)

Study finds potential danger to workers in food flavoring manufacturing
Workers in the food flavoring manufacturing industry may be at risk of developing an irreversible type of damage to the lungs, according to a study presented at the American Thoracic Society Conference in Atlanta on May 20. Researchers from the University of Cincinnati College of Medicine found five workers at a food flavoring manufacturing plant who developed bronchiolitis obliterans which leads to severe narrowing of the small airways. (2002-05-20)

Pain-Relieving Properties Of Pepper Rediscovered
The healing properties of red pepper or capsicum are being rediscovered by modern medicine, notes the January issue of the Penn State Sports Medicine Newsletter (1997-01-21)

Chili peppers and marijuana calm the gut
You wouldn't think chili peppers and marijuana have much in common. But when eaten, both interact with the same receptor in our stomachs, according to a paper by UConn researchers published in the April 24 issue of the journal Proceedings of the National Academy of Sciences. The research could lead to new therapies for diabetes and colitis, and opens up intriguing questions about the relationship between the immune system, the gut and the brain. (2017-04-24)

African mole-rats immune to 'wasabi pain'
A new report in Science provides the first evidence of a mammal -- the highveld mole-rat -- being immune to pain from exposure to allyl isothiocyanate, or AITC, the active ingredient of wasabi. (2019-05-30)

Spicy compound from chili peppers slows lung cancer progression
Findings from a new study show that the compound responsible for chili peppers' heat could help slow the spread of lung cancer, the leading cause of cancer death for both men and women. Most cancer-related deaths occur when cancer spreads to distant sites, a process called metastasis. (2019-04-06)

Immersion in virtual reality scenes of the Arctic helps to ease people's pain
Watching immersive 360 videos of icy Arctic scenes helps to relieve intense burning pain and could hold hope for treating chronic pain, a small study has found. (2019-11-08)

Study identifies gene that makes gentle touch feel painful after injury
In a study of four patients with a rare genetic disorder, NIH researchers found that the PIEZO2 gene may be responsible for tactile allodynia: the skin's reaction to injury that makes normally gentle touches feel painful. This and a second NIH-funded study showed how the gene may play an essential role in the nervous system's reaction to injury and inflammation, making PIEZO2 a target for developing precise treatments for relieving the pain caused by cuts, burns, and other skin injuries. (2018-10-10)

Experimental Biology highlights -- Cancer, neurodegenerative diseases and medical news
Embargoed press materials are now available for the Experimental Biology (EB) 2019 meeting, to be held in Orlando April 6-9. EB is the annual meeting of five scientific societies bringing together more than 12,000 scientists and 25 guest societies in one interdisciplinary community. (2019-04-03)

How taste response is hard-wired into the brain
Instantly reacting to the sweet lure of chocolate or the bitter taste of strychnine would seem to demand that such behavioral responses be so innate as to be hard-wired into the brain. Indeed, in studies with the easily manipulable fruit fly Drosophila, Kristin Scott and colleagues reported in the January 19, 2006, issue of Neuron experiments demonstrating just such a hard-wired circuitry. (2006-01-18)

Pain free, thanks to evolution
African mole-rats are insensitive to many different kinds of pain. As an international research team led by the MDC's Gary Lewin reports in Science, this characteristic has even allowed mole-rats to populate new habitats. Thanks to a genetic change, the highveld mole-rat is able to live alongside venomous ants with painful stings that other mole-rats avoid. (2019-05-30)

Researchers show how insect food choice can be manipulated
Researchers at the University of California, Riverside have found a way to access and manipulate taste neurons in the pharynx (throat) of the common fruit fly that could help control the spread of mosquito-related illnesses, such as dengue, malaria, yellow fever, and Zika virus, and reduce the loss of crops due to agricultural pests. (2017-12-05)

What's next in diets: Chili peppers?
A large percentage of the world's population -- fully one third, by the World Health Organization's estimates -- is currently overweight or obese. This staggering statistics has made finding ways to address obesity a top priority for many scientists around the globe, and now a group of researchers at the University of Wyoming has found promise in the potential of capsaicin -- the chief ingredient in chili peppers -- as a diet-based supplement. (2015-02-08)

Pain receptor in brain may be linked to learning and memory
For the first time, a Brown University research team has linked pain receptors found throughout the nervous system to learning and memory in the brain. The findings, published in Neuron, point up new drug targets for memory loss or epileptic seizures. (2008-03-13)

When hypothalamic cells warm up, feeding goes down: Exercise-induced appetite suppression
Exercise heats up the hypothalamus to drive down food intake, according to a study publishing on April 24 in the open-access journal PLOS Biology by Jae Hoon Jeong, Young-Hwan Jo, and colleagues at the Albert Einstein College of Medicine in New York. The findings answer a long-standing question about the cause of exercise-induced reduction in appetite. (2018-04-24)

Milk: Best drink to reduce burn from chili peppers
People who order their Buffalo wings especially spicy and sometimes find them to be too 'hot,' should choose milk to reduce the burn, according to Penn State researchers, who also suggest it does not matter if it is whole or skim. (2019-06-25)

Hot peppers really do bring the heat
Researchers have found that capsaicin, the active chemical in chili peppers, can induce thermogenesis, the process by which cells convert energy into heat. (2008-08-06)

An effective but painful treatment
Photodynamic therapy is an effective treatment for early-stage skin cancer. However, this therapy can cause patients severe pain. The reason for this was previous a mystery to researchers. Physiologists at Friedrich-Alexander Universität Erlangen-Nürnberg have now discovered that it is due to two specific ion channels. (2016-06-23)

Study finds association between eating hot peppers and decreased mortality
A large prospective study has found that consumption of hot red chili peppers is associated with a 13 percent reduction in total mortality. (2017-01-13)

Warning to those wanting to spice up their lives
Think twice before adding that extra kick of chili sauce or chopped jalapeno to your meal. New research involving the University of South Australia shows a spicy diet could be linked to dementia. (2019-07-22)

Tree shrews can tolerate hot peppers: Mutation in pain receptor makes peppery plant palatable
Almost all mammals avoid eating chili peppers and other 'hot' foods, because of the pain they induce. But not the tree shrew, according to a study publishing July 12 in the open-access journal PLOS Biology by Yalan Han of the Kunming Institute of Zoology in China, and colleagues. The researchers found that this close relative of primates is unaffected by the active ingredient in chili peppers due to a subtle mutation in the receptor that detects it. (2018-07-12)

New evidence that chili pepper ingredient fights fat
Capsaicin, the stuff that gives chili peppers their kick, may cause weight loss and fight fat buildup by triggering certain beneficial protein changes in the body, according to a new study on the topic. The report, which could lead to new treatments for obesity, appears in ACS' monthly Journal of Proteome Research. (2010-07-21)

'Ouch zone' in the brain identified
Activity in a brain area known as the dorsal posterior insula is directly related to the intensity of pain, an Oxford University brain imaging study people has found. These results could help detect pain in people with limited communication abilities. The research team now plans to verify these results by attempting to switch off this brain region in relevant patients suffering from intractable pain. (2015-03-09)

How to stop pain from serious burns using epigenetics
The unpleasant sensation sparked by the nervous system when confronted with a harmful stimulus can be alleviated by blocking a genetic marker that switches off the activity of the neurons involved. Jose Vicente Torres Pérez, a Spanish researcher who works at Imperial College in London, has trialled this innovative pain relief therapy on mice with serious burns. The aim is to use his findings to help burn victims. (2017-02-01)

Tarantula venom and chili peppers target same pain sensor
Venom from a West Indian tarantula has been shown to cause pain by exciting the same nerve cells in mice that sense high temperatures and the hot, spicy ingredient in chili peppers, UCSF scientists have discovered. (2006-11-08)

Study finds e-cigarette use linked to cough reflex sensitivity
The popularity of electronic cigarettes has steadily increased worldwide, but little is known about their effects on health. New research suggests that the single use of an electronic cigarette approximating the nicotine exposure of one tobacco cigarette reduces the sensitivity of the cough reflex. (2015-08-20)

Anesthetic approach stops pain without affecting motor function
One of the holy grails of local anesthesia is the ability to achieve a long-lasting nerve block that eliminates pain sensation while not affecting motor function. Now, researchers at Children's Hospital Boston have discovered an anesthetic approach that seems to do just that. (2010-02-01)

DMP for diabetes type 2: Current guidelines indicate some need for revision
As a literature search for recommendations from current clinical practice guidelines of high methodological quality has shown, there is no compelling need for revision of any part of the disease management program for diabetes type 2. However, in its final report now published, IQWiG identified various aspects that could be supplemented and specified. (2012-01-03)

News tips from the Journal of Neuroscience
The following articles are featured in the May 14 issue of the Journal of Neuroscience: (2008-05-13)

A highly sensitive detection for spicy tastes to choose kimchi of your preference!
The World Institute of Kimchi has announced that it has developed a new analytical tool for the ultra-trace ratiometric detection of capsaicinoids, an analysis method that can be easily applied to analyze the spicy tastes of kimchi in industrial fields. As a result, the team successfully devised a simple yet reliable ultrasensitive analytical technique that takes less than 30 mins, while its detection strength was improved by up to one million times. (2019-05-08)

Spice it up or just veg out, either way you may be helping to defend against cancer
Two new studies suggest that broccoli and red chili pepper may slow or prevent the growth of cancerous tumor cells. The findings, being presented by the University of Pittsburgh at the American Association for Cancer Research's annual meeting, April 16 to 20, at the Anaheim Convention Center in Anaheim, Ca., looked at the effect of these dietary agents on ovarian and pancreatic cancers and found that both were effective inhibitors of the cancer process. (2005-04-19)

The good cough and the bad cough
Researchers might be able to treat a troublesome cough in disease without disrupting the protective cough we need for optimal lung health, by targeting the different brain circuits involved. That's according to new research published today in The Journal of Physiology. (2020-10-07)

Scientists uncover dietary strategy to address obesity using component in red chili
Scientists have discovered a dietary strategy that may address obesity by reducing endotoxemia, a major contributor to chronic, low-grade inflammation (CLGI). The researchers uncovered an interaction between dietary capsaicin (CAP), the major pungent component in red chili, and gut microbiota. This novel mechanism for the anti-obesity effect of CAP acts through prevention of microbial dysbiosis. (2017-05-23)

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