Popular Chemotherapy News and Current Events

Popular Chemotherapy News and Current Events, Chemotherapy News Articles.
Sort By: Most Relevant | Most Recent
Page 1 of 25 | 1000 Results
IMpower131
Patients with Stage IV squamous non-small cell lung cancer enrolled in clinical trial to test the immunotherapy atezolizumab and chemotherapy against chemotherapy alone experienced a longer survival rate, among a subgroup of patients with high PD-LI. (2019-09-10)

Maintenance therapy with rucaparib shows clinical responses in a subgroup of patient with pancreatic cancer
Maintenance treatment with the PARP inhibitor rucaparib (Rubraca) was well tolerated and provided clinical responses among patients with advanced BRCA- or PALB2-mutated pancreatic cancer sensitive to platinum-based chemotherapy, according to results from an interim analysis of an ongoing phase II clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-04-02)

Forgoing chemo linked to worse survival in older patients with advanced colon cancer who had dementia
A pre-existing diagnosis of dementia was associated with increased risk of death for older patients with advanced colon cancer; however, some of the effects of dementia on survival could be mediated by receipt of chemotherapy. (2017-09-22)

New analytical technology to quantify anti-cancer drugs inside cancer cells
University of Oklahoma researchers will apply a new analytical technology that could ultimately provide a powerful tool for improved treatment of cancer patients in Oklahoma and beyond. Using mass spectrometry, an analytical instrument for sensitive detection and accurate identification of molecules, the team will quantitate the amount of anti-cancer drugs present in individual cancer cells, including those in bladder cancer cells isolated from patients undergoing chemotherapy. (2016-06-14)

Tuberculosis drugs work better with vitamin C
Studies in mice and in tissue cultures suggest that giving vitamin C with tuberculosis drugs could reduce the unusually long time it takes these drugs to eradicate this pathogen. The research is published in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology. (2018-01-03)

Delaying adjuvant chemo associated with worse outcomes for patients with triple-negative breast cancer
Patients with triple-negative breast cancer who delayed starting adjuvant chemotherapy for more than 30 days after surgery were at significantly higher risk for disease recurrence and death compared with those who started the treatment in the first 30 days after surgery, according to a retrospective study presented at the 2018 San Antonio Breast Cancer Symposium. (2018-12-05)

For patients with esophageal cancer, status of lymph nodes after preoperative therapy determines survival
The status of lymph nodes rather than the status of the primary tumor following preoperative neoadjuvant chemotherapy or chemoradiation therapy is the most important factor that determines whether patients with locally advanced esophageal cancer will survive. The study presented at the AATS 98th Annual Meeting indicates that while preoperative chemotherapy and radiation therapy improve survival of patients with esophageal cancer, patients with malignant lymph nodes following therapy were less likely to survive than patients with no cancer in the lymph nodes. (2018-05-01)

Can our genes help predict how women respond to ovarian cancer treatment?
New research, led by Professor Anna deFazio from the Westmead Institute and Westmead Hospital, has shown that the genes we inherit can have a significant impact on how the body processes chemotherapy drugs, which may lead to different clinical outcomes for ovarian cancer patients. (2018-02-15)

Nanoparticles deliver anticancer cluster bombs
Scientists have devised a triple-stage 'cluster bomb' system for delivering the chemotherapy drug cisplatin, via tiny nanoparticles designed to break up when they reach a tumor. (2016-03-29)

Huntsman Cancer Institute research holds promise for personalized lung cancer treatments
New research from scientists at Huntsman Cancer Institute (HCI) at the University of Utah uncovered distinct types of tumors within small cell lung cancer that look and act differently from one another. Scientists also identified a targeted drug combination that worked well with one specific tumor type. The study was published today in Cancer Cell. The findings suggest small cell lung cancer should not be treated as a uniform disease. (2017-01-12)

Study results offer another boon for PARP inhibitors in treatment of advanced breast cancer
Patients with certain advanced hereditary breast cancers may have new treatments options on the horizon, according to two studies presented this week at the annual San Antonio Breast Cancer Symposium. Susan Domchek, M.D., executive director of the Basser Center for BRCA at Penn's Abramson Cancer Center, will present new results from the Mediola and OlympiAD trials showing continued success of treating BRCA-related metastatic breast cancer with the PARP inhibitor olaparib with limited side effects for patients. (2017-12-08)

Biomarkers in breast cancer: IQWiG criticizes conclusion on MINDACT data in US guideline
In their updated guideline, US oncologists recently recommended the MammaPrint test. Researchers from IQWiG have reacted in a letter to the editor in the Journal of Clinical Oncology. (2017-12-27)

Advanced therapy offers cure for relapsed cancer patient
Testicular cancer patients who do not respond to traditional therapy can be cured with high-dose chemotherapy and a stem cell transplant, according to an Indiana University School of Medicine study by Lawrence Einhorn, M.D.; Stephen Williams, M.D.; Rafat Abonour, M.D., and colleagues published in the July 26 issue of the New England Journal of Medicine. Although the number of relapsed testicular cancer patients in the US is small, the IU Simon Cancer Center treats a majority of them. (2007-07-25)

Antibiotics may impact cancer treatment efficacy
There is mounting laboratory evidence that in the increasingly complex, targeted treatment of cancer, judicious use of antibiotics also is needed to ensure these infection fighters don't have the unintended consequence of also hampering cancer treatment, scientists report. (2018-03-02)

Researchers develop breakthrough technique to combat cancer drug resistance
The ability for cancer cells to develop resistance to chemotherapy drugs -- known as multi-drug resistance -- remains a leading cause for tumor recurrence and cancer metastasis, but recent findings offer hope that oncologists could one day direct cancer cells to 'turn off' their resistance capabilities. (2018-02-08)

Combination therapy more effective than chemotherapy alone for many newly diagnosed leukemia patients
A Phase II study pairing azacitidine with enasidenib boosts complete remission in patients with AML with IDH2 mutations. (2019-12-09)

Vitamin A may help improve pancreatic cancer chemotherapy
The addition of high doses of a form of vitamin A could help make chemotherapy more successful in treating pancreatic cancer, according to an early study by Queen Mary University of London. The promising initial results have led to the potential treatment being tested in a new clinical trial. (2016-05-24)

UofL offers vaccine trial for children with relapsed tumors at Kosair Children's Hospital
Children with relapsed tumors and their parents are finding hope in a Phase I research study led by Kenneth G. Lucas, M.D., at the University of Louisville who is making progress in developing a vaccine that one day could possibly prevent recurrence of some cancers. (2015-07-16)

Lymph node surgery could be avoided for some women with aggressive types of breast cancer
Sentinel lymph node biopsies, where lymph nodes are surgically removed to check for signs of breast cancer spread, could be safely avoided for some women, according to research presented at the 11th European Breast Cancer Conference. (2018-03-21)

How gut microbes help chemotherapy drugs
Two bacterial species that inhabit the human gut activate immune cells to boost the effectiveness of a commonly prescribed anticancer drug, researchers report Oct. 4 in Immunity. The study identifies a new role for Enterococcus hirae and Barnesiella intestinihominis in activating cancer-fighting T cell immune responses, thereby enhancing the effects of the chemotherapy drug cyclophosphamide. Moreover, this microbe-driven immune response predicted longer progression-free survival in advanced lung and ovarian cancer patients treated with chemo-immunotherapy. (2016-10-04)

First study of neoadjuvant use of PARP inhibitor shows promise for early-stage, BRCA+ breast cancer patients
In a small Phase II study of early-stage breast cancer patients with BRCA1/2 mutations, researchers at The University of Texas MD Anderson Cancer Center found that more than half of the women who took the PARP inhibitor talazoparib once daily prior to surgery had no evidence of disease at the time of surgery. If further validated in larger, confirmatory trials, the oral medication could replace chemotherapy for these patients. (2018-06-04)

Drug combo gangs up to take on triple-negative breast cancer
In the hunt for novel treatments against an aggressive form of breast cancer, researchers combined a new protein inhibitor with a chemotherapy drug to create a powerful combination that resulted in cancer cell death. (2017-09-26)

Anthracyclines improve survival in HER2-positive breast cancer patients
Treatment with the class of chemotherapy drugs called anthracyclines improves survival in women with HER2-positive breast cancer who have previously had surgery, but it may not offer any benefit for women with HER2-negative tumors, according to a study published online Dec. 25 in the Journal of the National Cancer Institute. (2007-12-25)

High EGFR expression a predictor for improved survival with cetuximab plus chemotherapy
High epidermal growth factor receptor (EGFR) expression was a good predictor of which lung cancer patients would survive longer when cetuximab (Erbitux) was added to first-line chemotherapy, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer. (2011-07-05)

Chemotherapy drug may increase vulnerability to depression
A chemotherapy drug used to treat brain cancer may increase vulnerability to depression by stopping new brain cells from growing, according to a new King's College London study out today in Translational Psychiatry. (2017-04-25)

Certain factors may predict lung cancer patients' response to chemotherapy
In a retrospective analysis of 73 lung squamous cell carcinoma patients treated with the chemotherapy regimen of gemcitabine plus cisplatin, higher body mass index and younger age were linked with longer progression-free survival, the length of time that a patient lives with cancer but it does not get worse. Patients with better response to treatment and higher body mass index had longer overall survival in the Thoracic Cancer analysis. (2018-01-10)

Additional therapy after surgical removal of rare tumors may not increase survival
Results of an analysis from the University of Cincinnati (UC) College of Medicine show that additional therapy, or adjuvant therapy, delivered after surgical removal of a rare type of gastrointestinal tumor does not increase survival rates for patients. (2018-03-24)

Sperm changes documented years after chemotherapy
A Washington State University researcher has documented epigenetic changes in the sperm of men who underwent chemotherapy in their teens. (2017-02-01)

How cells detect, mend DNA damage may improve chemotherapy
Human cells have a way of detecting and mending DNA damage caused by some common chemotherapy drugs, according to a new study from Washington University School of Medicine in St. Louis. The findings could have important implications for treating cancer. (2017-11-08)

Cell culture system could offer cancer breakthrough
A new cell culture system that provides a tool for preclinical cancer drug development and screening has been developed by researchers in the USA. The team, led by scientists from Princeton University, N.J., created a microfluidic cell culture device that allows the direct, real-time observation of the development of drug resistance in cancer cells. (2017-08-29)

Some primary care doctors not prepared to help with cancer treatment decisions
Research has shown patients are discussing initial cancer treatment options with their primary care doctors. And now a new study finds that a significant number of these physicians report notable gaps in their knowledge of cancer treatment options. (2019-02-12)

Biomarkers may help predict outcomes in gastric cancer patients who abuse alcohol
Alcohol consumption has been identified as a modifiable risk factor for cancers such as gastric cancer. A new report in the the American Journal of Pathology sheds light on how specific proteins interact with alcohol, and how that interplay impacts survival and response to platinum-based adjuvant chemotherapy in patients with gastric cancer who may or may not still be drinking. (2018-01-10)

New biomarkers for colorectal cancer
Researchers from the University of Luxembourg found a new biomarker for colorectal cancer (CRC) that might improve therapy and survival rates of patients. Biomarkers are measurable biological indicators for a specific disease, such as changes in the amounts of certain proteins that occur in combination with certain illnesses. Such biomarkers help physicians to diagnose a condition, identify the disease stage, and determine a patient's risk for recurrence of the disease. This supports the doctor in choosing the best-fitting treatment plan. (2018-01-11)

New CAR T case study shows promise in acute myeloid leukemia
According to a case study from trial published online ahead of print in the journal Haematologica, a patient has remained cancer free for nine months after being treated with CYAD-01, followed by a bone marrow transplant. (2018-05-09)

Use of chemotherapy for early stage breast cancer declines, Stanford-led study says
A study of nearly 3,000 women with early stage breast cancer indicates a recent, significant decline in the use of chemotherapy despite the lack of any change in national treatment recommendations or guidelines, according to researchers at the Stanford University School of Medicine and the University of Michigan. (2017-12-11)

Radiation-guided nanoparticles zero in on metastatic cancer
Zap a tumor with radiation to trigger expression of a molecule, then attack that molecule with a drug-loaded nanoparticle. (2016-06-29)

Novel diabetes drugs sensitize cancer cells to chemotherapy agents
Scientists at Dana-Farber Cancer Institute have shown that experimental diabetes drugs can make cancer cells more vulnerable to traditional chemotherapy agents, and they say such combinations should be explored to potentially improve outcomes for cancer patients. (2018-01-02)

Targeted therapy plus chemotherapy may pack 1-2 punch against melanoma
By targeting and disabling a protein frequently found in melanoma tumors, doctors may be able to make the cancer more vulnerable to chemotherapy, according to a new study by researchers in the Duke Comprehensive Cancer Center. (2008-05-15)

Research uncovers a potential new strategy to fight ovarian cancer
Researchers discovered a potential novel way to regulate ovarian cancer growth. (2018-03-28)

Protein analysis may reveal new cancer treatment targets
Researchers have used lab technology called mass spectrometry to study the proteins expressed by human cancer cells. (2018-06-15)

Page 1 of 25 | 1000 Results
   First   Previous   Next      Last   
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.