Popular Cord Blood News and Current Events

Popular Cord Blood News and Current Events, Cord Blood News Articles.
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NIH-funded study suggests acetaminophen in pregnancy linked to higher risk of ADHD, autism
Exposure to acetaminophen in the womb may increase a child's risk for attention deficit/hyperactivity disorder and autism spectrum disorder, suggests a study funded by the National Institutes of Health and the Agency for Health Care Research and Quality. (2019-10-30)

ALS neuron damage reversed with new compound
Scientists have identified the first compound that eliminates the ongoing degeneration of upper motor neurons that become diseased and are a key contributor to ALS (amyotrophic lateral sclerosis), a swift and fatal neurodegenerative disease that paralyzes its victims. In ALS, movement-initiating nerve cells in the brain and muscle-controlling nerve cells in the spinal cord die. After administering the new compound,, the diseased brain neurons stopped degenerating so much that they became similar to healthy control neurons after 60 days of treatment. (2021-02-23)

High blood pressure may make it difficult for the elderly to think clearly
Adding another reason for people to watch their blood pressure, a new study from North Carolina State University shows that increased blood pressure in older adults is directly related to decreased cognitive functioning, particularly among seniors with already high blood pressure. This means that stressful situations may make it more difficult for some seniors to think clearly. (2008-12-15)

Transplanting adult spinal cord tissues: A new strategy of repair spinal cord injury
Spinal cord injury repair is one of the most challenging medical problems, and no effective therapeutic methods has been developed. Now researchers from China reported transplantation of adult spinal cord tissue for treatment of adult complete spinal cord injury. This work provided valuable information for future clinical application. (2019-03-27)

Neurons that regenerate, neurons that die
In a new study published in Neuron, investigators report on a transcription factor that they have found that can help certain neurons regenerate, while simultaneously killing others. (2017-06-21)

Gene medication to help treat spinal cord injuries
The two-gene medication has been proven to recover motor functions in rats. After several months of treatment, rodents were able to use previously paralyzed limbs. Researchers at Kazan Federal University are now seeking pre-clinical trial investment. (2019-03-18)

3-D printing helps treat woman with spinal condition
Clinicians recently used 3-D printing to help treat a woman with a degenerative condition of the spinal column. (2017-04-20)

From spinal cord injury to recovery
Spinal cord injury disconnects communication between the brain and the spinal cord, disrupting control over part of the body. Studying the mechanisms of recovery, Leuven researcher Aya Takeoka (NERF) found that a specific type of neuronal feedback from sites below the injury plays a crucial role during early recovery and for maintaining regained motor functions. (2019-04-08)

A protein makes the difference
It is well-established knowledge that blood vessels foster the growth of tumors. Preventing the formation of tumors is a standard part of cancer therapy. A study by researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg has discovered a new, surprising role played by blood vessels: under certain conditions they can inhibit tumor growth. (2016-10-18)

Why do we develop high blood pressure?
Abnormally high blood pressure, or hypertension, may be related to changes in brain activity and blood flow early in life. That's according to a study conducted on a rat model of high blood pressure, published in Experimental Physiology. (2017-03-09)

Stem cell scientists discover genetic switch to increase supply of stem cells from cord blood
International stem cell scientists, co-led in Canada by Dr. John Dick and in the Netherlands by Dr. Gerald de Haan, have discovered the switch to harness the power of cord blood and potentially increase the supply of stem cells for cancer patients needing transplantation therapy to fight their disease. (2016-07-14)

Study shows area undamaged by stroke remains so, regardless of time stroke is left untreated
A study led by Achala Vagal, M.D., associate professor at the University of Cincinnati College of Medicine and a UC Health radiologist, looked at a group of untreated acute stroke patients and found that there was no evidence of time dependence on damage outcomes for the penumbra, or tissue that is at risk of progressing to dead tissue but is still salvageable if blood flow is returned in a stroke, but rather an association with collateral flow -- or rerouting of blood through clear vessels. (2016-05-25)

Here's something that will raise your blood pressure
The apelin receptor (APJ) has been presumed to play an important role in the contraction of blood vessels involved in blood pressure regulation. A University of Tsukuba-led research team found that APJ was closely associated with hypertension through effects on vascular smooth muscle cells in laboratory mice. In addition, APJ worked synergistically with the α1A-adrenergic receptor to cause vasoconstriction. These results may help to understand blood pressure regulation and support therapies for vascular diseases. (2019-11-01)

Novel device and staff education lead to lower blood culture contamination rates
A Medical University of South Carolina study found that use of a mechanical initial specimen diversion device (ISDD®) and staff education led to a nearly four-fold decrease in contaminated blood cultures that was sustained over 20 months. (2018-01-24)

Leadership and adaptive reserve are not associated with blood pressure control
Primary care leadership and practice resilience can strengthen organizational culture. In small primary care practices, however, practice adaptive reserve and leadership capability are not associated with baseline blood pressure control. (2018-04-09)

'Pulling' bacteria out of blood
Magnets instead of antibiotics could provide a possible new treatment method for blood infection. This involves the blood of patients being mixed with magnetic iron particles, which bind the bacteria to them after which they are removed from the blood using magnets. The initial laboratory tests at Empa in St. Gallen have been successful, and seem promising. (2016-12-07)

Improving cell transplantation after spinal cord injury: When, where and how?
Spinal cord injuries are mostly caused by trauma, often incurred in road traffic or sporting incidents, often with devastating and irreversible consequences. According to a systematic analysis of 49 animal studies published this week in PLOS Biology by Ralf Watzlawick, Jan Schwab and colleagues, after experimental spinal cord injury, transplanting olfactory ensheathing cells (OECs) into the site of damage significantly improves locomotor performance. (2016-05-31)

Loosen up!
Generally, exercise is considered good for you. However, physicians and medical doctors previously prescribed bedrest to people with heart failure, fearing exercise could potentially lead to additional health problems. (2019-10-22)

Neurons modulate the growth of blood vessels
A team of researchers at Karlsruhe Institute of Technology shake at the foundations of a dogma of cell biology. By detailed series of experiments, they proved that blood vessel growth is modulated by neurons and not, as assumed so far, through a control mechanism of the vessel cells among each other. The results are groundbreaking for research into and treatment of vascular diseases, tumors, and neurodegenerative diseases. The study will be published in the prestigious journal Nature Communications. (2017-01-10)

New properties of sulfur atom discovered
2019 will be, as proclaimed by the UN, the 'International Year of the Periodic Table of Chemical Elements', in commemoration of the 150th anniversary of its creation. Researchers from the Faculty of Science of the University of Malaga (UMA) have recently revealed new properties of one of its key elements: sulfur. (2018-12-14)

Predictive value of blood pressure, heart rate, and blood pressure/heart rate ratio in a Chinese subpopulation with vasovagal syncope
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.1266, Zhuzhi Wen, Jingying Hou, Zun Mai, Huifen Huang, Yangxin Chen, Dengfeng Geng and Jingfeng Wang from Sun Yat-sen University, Guangzhou, China and Guandong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, China consider predictive value of blood pressure, heart rate, and blood pressure/heart rate ratio in a Chinese subpopulation with vasovagal syncope. (2021-01-22)

MBL scientists identify gene partnerships that promote spinal cord regeneration
Scientists at the Marine Biological Laboratory (MBL) have identified gene 'partners' in the axolotl salamander that, when activated, allow the neural tube and associated nerve fibers to functionally regenerate after severe spinal cord damage. Interestingly, these genes are also present in humans, though they are activated in a different manner. Their results are published this week in Nature Communications Biology. (2019-03-06)

Guards of the human immune system unraveled
Dendritic cells represent an important component of the immune system: they recognize and engulf invaders, which subsequently triggers a pathogen-specific immune response. Scientists of the University Hospital Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg and the LIMES Institute of the University of Bonn gained substantial knowledge of human dendritic cells, which might contribute to the development of immune therapies in the future. The results were recently published in the journal Science Immunology. (2016-12-16)

Time to reassess blood-pressure goals
High blood pressure or hypertension is a major health problem that affects more than 70 million people in the US, and over one billion worldwide. Despite being a critically important risk factor for heart and kidney disease, defining the 'optimal' blood pressure has been a challenge. (2015-11-09)

FDA approves Bystolic, a novel beta blocker
The US Food and Drug Administration has approved Bystolic (nebivolol) for the treatment of hypertension, also known as high blood pressure. Bystolic works differently than many older beta blockers in that it is preferentially beta 1 selective at doses less than or equal to 10 mg, meaning it selectively blocks the effects of adrenaline at the heart. In addition, Bystolic vasodilates -- or widens and expands -- the blood vessels. (2007-12-18)

Sensor for blood flow discovered in blood vessels
The PIEZO1 cation channel translates mechanical stimulus into a molecular response to control the diameter of blood vessels. (2016-11-10)

Spinal cord injury research: Bonus benefit to activity-based training
Researchers in the Kentucky Spinal Cord Injury Research Center (KSCIRC) at the University of Louisville have discovered that the training, designed to help individuals with SCI improve motor function, also leads to improved bladder and bowel function and increased sexual desire. (2018-01-31)

A review on the therapeutic antibodies for spinal cord injury
Spinal cord injury (SCI) causes long-lasting damage in the spinal cord that leads to paraparesis, paraplegia, quadriplegia and other lifetime disabilities. The emergence of antibody treatment has paved a new pathway for the management of SCI. In this current review, Professor Weijiang Zhao and Doctor Danyang Tang summarize the experimentally therapeutic application of antibodies in SCI. (2016-10-03)

MRI analysis with machine learning predicts impairment after spinal injury, study shows
A test of machine-learning algorithms shows promise for computer-aided prognosis of acute spinal cord injury, according to a study to be presented at the ARRS 2018 Annual Meeting, set for April 22-27 in Washington, D.C. (2018-04-05)

U of M begins nation's first clinical trial using T-reg cells from cord blood in leukemia treatment
University of Minnesota researchers have initiated a ground breaking clinical trial to determine the optimal dose and safety of T regulatory cells (T-regs) to decrease the risk of immune reactions common in patients undergoing blood and marrow transplantation. (2007-09-05)

New tool to improve blood pressure measurement
Oxford University researchers have developed a prediction model that uses three separate blood pressure readings taken in a single consultation and basic patient characteristics to give an adjusted blood pressure reading that is significantly more accurate than existing models for identifying hypertension. (2016-03-21)

Stem cells found in adult skin can be transplanted and function in mouse models of disease
Researchers at The Hospital for Sick Children (SickKids) and the University of Calgary have found that stem cells derived from adult skin can create neural cell types that can be transplanted into and function in mouse models of disease. This research is reported in the June 14, 2006 issue of The Journal of Neuroscience. (2006-06-14)

Scientists find new antimalarial drug targets
Researchers have discovered crucial new processes that allow malaria parasites to escape red blood cells and infect other cells, offering potential new treatment targets. The team are already working with pharmaceutical companies to use this knowledge to develop new antimalarial drugs - a critical step in the battle against drug-resistant malaria. (2018-02-20)

Neurological signals from the spinal cord surprise scientists
With a study of the network between nerve and muscle cells in turtles, researchers from the University of Copenhagen have gained new insight into the way in which movements are generated and maintained. In the long term, the new knowledge may have an impact on the treatment of, for example, ALS and spinal cord injuries. (2019-09-19)

Generating improvement in spinal cord injuries
Results from an ongoing treatment for spinal cord injury research study were announced on Jan. 24 in a conference held by Asterias, the biotechnology company that manufactures AST-OPC1. (2017-01-24)

Spinal cord injury patients face many serious health problems besides paralysis
Spinal cord patients are at higher risk for cardiovascular disease; pneumonia; life-threatening blood clots; bladder, bowel and sexual dysfunction; constipation and other gastrointestinal problems; pressure ulcers; and chronic pain, according to a report published in the journal Current Neurology and Neuroscience Reports. (2017-02-15)

Spinal cord injury research hampered by animal models, says new study
Research on traumatic spinal cord injuries is hampered by a reliance on animal experiments that don't accurately predict human outcomes, says a new study in the upcoming edition of the peer-reviewed journal Reviews in the Neurosciences. The review was written by scientists with the Physicians Committee for Responsible Medicine. (2008-04-28)

Protein shown to play a key role in normal development of nervous system
A protein that enables nerve cells to communicate with each other plays a key role in controlling the developing nervous system. Research into how that protein helps precise connections to form among nerve cells may provide a basis for eventual treatments for patients who suffer injuries to their nervous system, including spinal cord injury. (2008-10-07)

Protective effect of genetically modified cord blood on spinal cord injury in rats
Researchers of Kazan Federal University genetically modified cord blood which managed to increase tissue sparing and numbers of regenerated axons, reduce glial scar formation and promote behavioral recovery when transplanted immediately after a rat contusion spinal cord injury. (2016-04-08)

Bristol researchers use gene editing to improve red blood cell transfusion compatibility
Synthetic biologists at the University of Bristol have succeeded in generating laboratory-made red blood cells with rare blood group types that could one day be used to help patients who cannot be matched with donor blood. (2018-04-27)

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