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Popular Diabetic Retinopathy News and Current Events, Diabetic Retinopathy News Articles.
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Potential enzyme as therapeutic target for diabetes
Researchers from Kanazawa University and the National Centre for Global Health and Medicine in Tokyo report, in Nature Communications, a new mechanism for regulating glucose uptake by the liver which has implications for type 2 diabetes and its treatment. (2018-01-26)

Paradigm shift in the diagnosis of diabetes
A completely new classification of diabetes which also predicts the risk of serious complications and provides treatment suggestions. We are now seeing the first results of ANDIS -- a study covering all newly diagnosed diabetics in southern Sweden -- published in The Lancet Diabetes & Endocrinology. (2018-03-01)

Microbiomes of diabetic foot ulcers are associated with clinical outcomes
New research suggests that the microbial communities associated with chronic wounds common in diabetic patients affect whether those wounds heal or lead to amputations. (2019-04-18)

Diabetes: Are high blood glucose levels an effect rather than the cause of the disease?
Insulin resistance and elevated blood glucose levels are considered to be the cause of type 2 diabetes. However, scientists from the German Cancer Research Center (DKFZ) and Heidelberg University Hospital have now provided evidence that things might be completely different. They showed in flies that elevated levels of the metabolite MG (methylglyoxal) cause the typical diabetic disturbances of the metabolism and lead to insulin resistance, obesity and elevated blood sugar levels. (2018-03-15)

Blood vessel protein reverses macular degeneration, diabetic retinopathy in mice
Two major eye diseases and leading causes of blindness -- age-related macular degeneration and diabetic retinopathy -- can be reversed or even prevented by drugs that activate a protein found in blood vessel cells, researchers at the University of Utah School of Medicine and several other institutions have announced in a new study. (2008-03-16)

Telemedicine provides accurate diagnosis of rare cause of blindness in preemies
Accurately detecting a rare, but devastating cause of blindness in premature babies can be done as effectively with telemedicine as with traditional, in-person eye exams, a study published in JAMA Ophthalmology suggests.The finding could enable more blindness-preventing treatment for infants born in rural and other areas where there are few ophthalmologists trained to detect the condition, called retinopathy of prematurity, or ROP. (2018-04-06)

World's largest clinical specialty database yields critical insights
The American Academy of Ophthalmology today announced key milestones and clinical insights from studies powered by its clinical database. The IRIS® Registry (Intelligent Research In Sight) has amassed more than 41.2 million unique patients in its database, representing 166.2 million patient visits, covering 11 percent of the US population. (2017-11-13)

Weight loss drug shows positive effect on diabetes
'Now we report that, when added to lifestyle interventions, lorcaserin significantly reduced incidence of diabetes, increased rates of diabetes remission, and reduced the risk of diabetic microvascular complications.' (2018-10-04)

Changes of the cell environment are associated with certain eye diseases
In case of ischemic injury to the retina, changes occur in the protein scaffold in the environment of retinal cells, the so-called extracellular matrix. Various eye diseases, such as glaucoma, are associated with such ischemic events. Researchers at Ruhr-Universität Bochum describe how the extracellular matrix is affected by these processes in the journal Scientific Reports. (2017-03-15)

Eye and heart complications are tightly linked in type 1 diabetes
People with chronic kidney disease have much higher risk of cardiovascular disease, the leading cause of death for those with type 1 diabetes. In a paper published in Diabetes Care, the Joslin team demonstrated that the eye condition known as proliferative diabetic retinopathy also is independently associated with cardiovascular disease. (2018-01-31)

Smartphone-controlled cells help keep diabetes in check
Cells engineered to produce insulin under the command of a smartphone helped keep blood sugar levels within normal limits in diabetic mice, a new study reports. (2017-04-26)

Building the batteries of cells
A new study, led by Dr. Ruchika Anand and Prof. Andreas Reichert, Heinrich-Heine-University Duesseldorf, Institute of Biochemistry and Molecular Biology I, Germany, now found that two lipid-binding proteins located inside of mitochondria control the overall stability of these batteries. This study provides the first link between mitochondrial structure, lipids and assembly of large respiratory protein units of mitochondria and their importance in diabetes and heart diseases. (2020-08-11)

A drug to treat retinal diseases with drops instead of injections
The Spanish firm Sylentis has developed a compound to treat diseases of the retina, such as age-related macular degeneration and diabetic retinopathy, which will be administered by ophthalmic drops instead of intraocular injections. The drug, which has been tested in animals, is a small interfering RNA capable of penetrating the cells of the retina and blocking the formation of new blood vessels. (2017-12-12)

Prediabetes patients at heightened risk for cardiovascular and chronic kidney diseases
Researchers at the Emory Rollins School of Public Health and US Centers for Disease Control and Prevention have found that high proportions of patients with prediabetes are at substantial risk for cardiovascular disease and chronic kidney disease. (2018-03-01)

Metabolites altered in chronic kidney disease
A new study that included researchers from Norway, the University of Washington, the University of California San Diego and The University of Texas Health Science Center at San Antonio (now called UT Health San Antonio™) found that dozens of small molecules called metabolites are altered in this disease. (2017-11-22)

Guidelines address self-management of hospitalized diabetes patients
It is important that patients with diabetes be involved in decisions concerning the management of their condition while they are hospitalized. (2018-06-20)

Mature B lymphocytes accelerate the healing of diabetic ulcers, other skin injuries
A Massachusetts General Hospital research team has found a surprising potential solution to a persistent clinical problem -- the healing of chronic wounds. The researchers report that application of mature B lymphocytes -- best known for producing antibodies -- greatly accelerated the healing of acute and chronic wounds in both diabetic and nondiabetic mice. (2017-10-25)

Vegetarian diets almost twice as effective in reducing body weight, study finds
Dieters who go vegetarian not only lose weight more effectively than those on conventional low-calorie diets but also improve their metabolism by reducing muscle fat, a new study published in the Journal of the American College of Nutrition has found. (2017-06-12)

Controlling blood sugar in hospitalized patients saves lives
If you are not diabetic and you are hospitalized, your blood sugar level is probably the last thing on your mind. But the fact is that high blood sugar during hospitalization for serious illness increases your risk of infection and death. Roughly one third of patients experience hyperglycemia, or high blood sugar, during their hospital stay, and many of those patients don't have diabetes or are undiagnosed. (2006-04-04)

Limited health literacy is a major barrier to heart disease prevention and treatment
Limited health literacy is a major barrier to heart health and managing heart disease and stroke. Health literacy is essential to navigate the health care system, use medication effectively and improve heart-healthy behaviors. (2018-06-04)

Protective effects of ADM-RAMP2 system make it a new therapeutic target for retinal vein occlusion
A clot in the retinal vein can lead to severe and irreversible loss of vision. In a report in The American Journal of Pathology investigators utilize a newly developed model of central retinal vein occlusion (CRVO) in mice that mimics many of the clinical features of CRVO in humans to study the pathologic effects of retinal occlusion and demonstrate the retinoprotective effects of the peptide adrenomedullin (ADM) and its receptor activity-modifying protein RAMP2. (2019-01-15)

What primary care providers should know about diabetic neuropathy
Researchers at Michigan Medicine led a group of internationally recognized endocrinologists and neurologists from both sides of the Atlantic and teamed up with the American Diabetes Association to craft a new position statement on the prevention, treatment and management of diabetic neuropathy. (2017-01-30)

Renoprotective effects of sglt2 inhibitors: Beyond glucose reabsorption inhibition
In this manuscript we summarize the available data on the mechanisms that underlie the renoprotective properties of SGLT2 inhibitors. Apart from their beneficial effects on carbohydrate and uric acid metabolism and their blood pressure-lowering properties, the most important mechanism that can explain the reduction in albuminuria and the preservation of renal function that follows their administration is the reduction in intraglomerular pressure. (2017-01-20)

Individual stress susceptibility and glucose metabolism are linked to brain function
Researchers at the Department for Psychiatry and Psychotherapy at the Mainz University Medical Center and the German Resilience Center (DRZ) in Mainz have now discovered that stress-induced mental disturbances in mice are directly linked to abnormal glucose metabolism. Normalizing the stress-induced alterations in glucose levels, using the anti-diabetic drug empagliflozin, restored spatial memory as well as long-term glucose metabolism. (2018-10-24)

Nature could provide the answer for blindness caused by diabetes, say experts
Mother Nature could have the answer to treating several causes of blindness, according to a ground-breaking study involving scientists from the University of Surrey and the Eugene and Marilyn Glick Eye Institute at Indiana University School of Medicine in the USA. (2019-04-09)

Possible link found between diabetes and common white pigment
In a pilot study by a team of researchers at The University of Texas at Austin, crystalline particles of titanium dioxide -- the most common white pigment in everyday products ranging from paint to candies -- were found in pancreas specimens with Type 2 diabetes, suggesting that exposure to the white pigment is associated with the disease. (2018-06-20)

University of Pittsburgh leads major national study on treating patients who have diabetes and heart disease
Recruitment has begun for a national, 40-center study that will determine the best way to treat patients who have coronary artery disease and type 2 diabetes. CAD is the top killer of people with type 2 diabetes. The University of Pittsburgh's Graduate School of Public Health is coordinating the study. (2001-06-14)

Type 2 diabetes: The costs of treating complications
Scientists at the Helmholtz Zentrum München have examined health insurance data of more than 300,000 people with diabetes in Germany. Their report, published in the medical journal 'Diabetes Care', breaks down the costs involved in treating various complications of the disease. The Helmholtz authors are members of the German Center for Diabetes Research (DZD). (2018-02-05)

Surgery better than drugs for serious lack of blood flow to the heart
Surgery or angioplasty to improve blood flow in patients with moderate to severe levels of blood flow restriction to the heart reduces the risk of cardiac death more than medication alone, researchers report in today's rapid access issue of Circulation: Journal of the American Heart Association. (2003-05-26)

Pain-relief drug may prevent lung problems, blindness in premature infants
A popular pain-relief drug may prevent lung and eye disorders common in premature infants, a UC Irvine College of Medicine study has found. (2002-10-19)

At-home vision monitoring app may improve patient care
Patients with age-related macular degeneration or diabetic retinopathy who used a mobile application to test their vision at home got comparable results to in-office vision testing, according to research presented today at AAO 2017, the 121st Annual Meeting of the American Academy of Ophthalmology. (2017-11-13)

Beating kidney disease together
Chronic kidney disease is a frequently encountered disorder: more than 10% of the population suffer from such problems. In a large proportion of these cases, the kidney damage is diabetes-induced. Universitätsklinikum Erlangen of Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) has joined forces with around 30 international partners in a consortium which aims to improve therapeutic options. (2017-03-03)

New oral diabetes drug shows promise in phase 3 trial for patients with type 1 diabetes
A University of Colorado Anschutz Medical Campus study finds sotagliflozin helps control glucose and reduces the need for insulin in patients with type 1 diabetes. Principal results were published today in the New England Journal of Medicine of a global Phase 3 clinical trial in patients with type 1 diabetes treated with sotagliflozin. Sotagliflozin has shown promise in improving glucose control without any increase in severe hypoglycemia or diabetic ketoacidosis compared to insulin alone. (2017-09-13)

Insulin therapy initially declined and delayed by an average of 2 years
Thirty percent of type 2 diabetic patients don't begin insulin when it's initially recommended, with the average start time being two years later. (2017-09-14)

A risk factor for drug-induced skin disease identified
Researchers have identified a type of human leukocyte antigen (HLA) that is associated with the skin disease bullous pemphigoid (BP) in diabetic patients administered with DPP-4 inhibitory drugs. (2017-12-06)

New approach to insulin treatment improves patients' lives
Training patients with diabetes to adjust their insulin doses to match their food choices, improves diabetes control and quality of life, finds a study in this week's BMJ. (2002-10-03)

Robocalls improve diabetes eye screening among low-income minorities
Automated reminder calls may be an effective tool to improve screening for diabetic eye disease among low-income minority patients, especially African Americans, a new study finds. The study results will be presented Monday at ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago, Ill. (2018-03-19)

Healthy fats improve nerve function in obese mice
Swapping dietary saturated fats for monounsaturated fats reverses nerve damage and restores nerve function in male mice, finds new preclinical research published in JNeurosci. These data support further investigation of diets rich in healthy fats as a potential treatment for the nerve damage that occurs with diabetes, known as diabetic neuropathy. (2019-03-18)

While men lose more weight on low-carb diets, women show improved artery flexibility
According to the Centers for Disease Control and Prevention, an estimated 1 out of 3 American adults live with higher than normal blood sugar levels known as prediabetes. Researchers from the University of Missouri School of Medicine recently found that while men may lose more weight on low-carb diets, women actually see better improvements in artery flexibility. It's a finding that may help pre-diabetic women reduce their risk for heart disease through a low-carb diet. (2018-07-17)

Mild cognitive impairment patients take about 3 medications for concomittant diseases
Dr. Vasileios Papaliagkas, the corresponding author of the paper, pointed that the vast majority of MCI patients were taking at least one medication, whereas slightly less than half of the patients (40 percent) took at least four medications. The types of medications that were most often taken for concomitant diseases were cardiovascular drugs, antidepressants, sedatives, thyroid drugs and anti-diabetic drugs. (2016-11-14)

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